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COLLABORATIVE AGREEMENTS (Details Narrative) - USD ($)
3 Months Ended 12 Months Ended
Mar. 31, 2023
Mar. 31, 2022
Dec. 31, 2015
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]      
Number of stock options vested 25,594    
Research and development expense $ 348,031 $ 669,838  
Research Agreements [Member]      
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]      
Research and development expense $ 0 $ 0  
University of Toronto [Member]      
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]      
Share-based compensation stock options, grants     6,250
Share-based compensation weighted average exercise price     $ 4.00
Share-based payment award, expiration period     10 years
Dr. David Lovejoy [Member] | Share-Based Payment Arrangement, Option [Member]      
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]      
Share-based compensation stock options, grants 138,325    
Number of stock options vested 105,721    
Number of stock options expired 31,250    
Options expiration date, description These have an exercise price of $4.00, $5.00 or $7.00 and are exercisable over a period ranging from 10 to 13 years.