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CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($) $ in Thousands | 12 Months Ended
--- | ---
Dec. 31, 2020 | Dec. 31, 2019 | Dec. 31, 2018
OPERATING ACTIVITIES: |  |  |
Comprehensive loss | $ (76,173) | $ (42,304) | $ (38,820)
Adjustments in respect of income and expenses not involving cash flow: |  |  |
Share-based compensation to employees and service providers | 4,202 | 3,027 | 2,678
Depreciation | 1,710 | 997 | 90
Amortization and impairment of intangible assets | 7,035 | 216 |
Non-cash interest expenses related to borrowing and payable in respect of intangible assets purchase and royalty obligation | 6,032 |  |
Fair value adjustments on derivative financial instruments |  | (344) | (104)
Fair value losses (gains) on financial assets at fair value through profit or loss | 94 | (27) | 137
Exchange differences and revaluation of bank deposits | 101 | 24 | 138
Total adjustments in respect of income and expenses not involving cash flow | 19,174 | 3,893 | 2,939
Changes in assets and liability items: |  |  |
Decrease (increase) in trade receivables | (27,439) | (258) | 570
Decrease (increase) in prepaid expenses and other receivables | (3,277) | (368) | 1,414
Increase in inventories | (4,644) | (1,113) | (116)
Increase (decrease) in accounts payable | 7,369 | 860 | (1,481)
Increase (decrease) in accrued expenses and other liabilities | 19,335 | (2,726) | 722
Increase in allowance for deductions from revenue | 17,076 | 1,267 | 310
Total changes in assets and liability items | 8,420 | (2,338) | 1,419
Net cash used in operating activities | (48,579) | (40,749) | (34,462)
INVESTING ACTIVITIES: |  |  |
Purchase of fixed assets | (406) | (168) | (23)
Purchase of intangible assets | (53,368) | (35) | (35)
Change in investment in current bank deposits | 10,200 | (2,069) | 4,869
Purchase of financial assets at fair value through profit or loss |  | (4,325) | (6,976)
Proceeds from sale of financial assets at fair value through profit or loss | 7,925 | 11,761 | 7,517
Net cash provided by (used in) investing activities | (35,649) | 5,164 | 5,352
FINANCING ACTIVITIES: |  |  |
Proceeds from issuance of ordinary shares, net of issuance costs | 23,867 | 36,300 | 41,902
Exercise of options into ordinary shares | 52 | 5 | 361
Proceeds from long-term borrowing, net of transaction costs | 78,061 |  |
Increase in restricted cash | (20,000) |  |
Decrease in restricted cash | 4,000 |  |
Payment of principal with respect to lease liabilities | (1,610) | (796) |
Repayment of payable in respect of intangible asset purchase |  |  | (500)
Net cash provided by financing activities | 84,370 | 35,509 | 41,763
INCREASE (DECREASE) IN CASH AND CASH EQUIVALENTS | 142 | (76) | 12,653
EXCHANGE DIFFERENCES ON CASH AND CASH EQUIVALENTS | 130 | 94 | (103)
BALANCE OF CASH AND CASH EQUIVALENTS AT BEGINNING OF PERIOD | 29,023 | 29,005 | 16,455
BALANCE OF CASH AND CASH EQUIVALENTS AT END OF PERIOD | 29,295 | 29,023 | 29,005
SUPPLEMENTARY INFORMATION ON INTEREST RECEIVED IN CASH | 414 | 753 | $ 728
SUPPLEMENTARY INFORMATION ON INTEREST PAID IN CASH | 6,654 | 251 |
Acquisition of right-of-use assets by means of lease liabilities | 2,930 | 2,805 |
Purchase of intangible assets posted as payable | 24,619 |  |
Purchase of an intangible asset in consideration for issuance of shares | $ 1,914 | $ 11,788 |

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- Definition The cash outflow for the purchases of intangible assets, classified as investing activities. [Refer: Intangible assets other than goodwill] + References Reference 1: http://www.xbrl.org/2003/role/exampleRef -Name IAS -Number 7 -IssueDate 2020-01-01 -Paragraph 16 -Subparagraph a -URI http://eifrs.ifrs.org/eifrs/xifrs-link?type=IAS&num=7&code=ifrs-tx-2020-en-r&anchor=para_16_a&doctype=Standard -URIDate 2020-01-01 + Details
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- Definition The cash outflow for the purchases of property, plant and equipment, classified as investing activities. [Refer: Property, plant and equipment] + References Reference 1: http://www.xbrl.org/2003/role/exampleRef -Name IAS -Number 7 -IssueDate 2020-01-01 -Paragraph 16 -Subparagraph a -URI http://eifrs.ifrs.org/eifrs/xifrs-link?type=IAS&num=7&code=ifrs-tx-2020-en-r&anchor=para_16_a&doctype=Standard -URIDate 2020-01-01 + Details
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- Definition The amount of acquisition of right-of-use assets by means of lease liabilities. + References No definition available. + Details
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- Definition Adjustments for change in investment in current bank deposits classified as investing activities. + References No definition available. + Details
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- Definition Adjustments for decrease (increase) in accrued expenses to reconcile profit (loss) to net cash flow from (used in) operating activities. + References No definition available. + Details
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- Definition Adjustments for increase (decrease) in allowance for deductions from revenue. + References No definition available. + Details
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- Definition Adjustments for revaluation of bank deposits. + References No definition available. + Details
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- References No definition available. + Details
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- Definition Amount of cash inflow associated with funds that are not available for withdrawal or use (such as funds held in escrow) and are associated with underlying transactions that are classified as investing activities. + References No definition available. + Details
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- Definition Amount of cash outflow associated with funds that are not available for withdrawal or use (such as funds held in escrow) and are associated with underlying transactions that are classified as investing activities. + References No definition available. + Details
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- Definition The amount of intangibles that an Entity acquires in a noncash (or part noncash) acquisition. Noncash is defined as information about all investing and financing activities of an enterprise during a period that affect recognized assets or liabilities but that do not result in cash receipts or cash payments in the period. "Part noncash" refers to that portion of the transaction not resulting in cash receipts or cash payments in the period. + References No definition available. + Details
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- Definition The cash inflow (outflow) related to non-current borrowings obtained. + References No definition available. + Details
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- Definition The cash inflow from the exercise of warrants and options. + References No definition available. + Details
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- Definition Repayment of payable in respect of intangible asset purchase + References No definition available. + Details
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- Definition Supplemental information on interest paid in cash. + References No definition available. + Details
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- Definition Supplementary information on investing activities related to the purchase of intangible assets not involving cash flows. + References No definition available. + Details
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