<SEC-DOCUMENT>0001140361-21-022578.txt : 20210628
<SEC-HEADER>0001140361-21-022578.hdr.sgml : 20210628
<ACCEPTANCE-DATETIME>20210628172547
ACCESSION NUMBER:		0001140361-21-022578
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		2
CONFORMED PERIOD OF REPORT:	20210624
FILED AS OF DATE:		20210628
DATE AS OF CHANGE:		20210628

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Fanucci Marsha
		CENTRAL INDEX KEY:			0001298814

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-38787
		FILM NUMBER:		211054634

	MAIL ADDRESS:	
		STREET 1:		MILLENNIUM PHARMACEUTICALS, INC.
		STREET 2:		40 LANDSDOWNE STREET
		CITY:			CAMBRIDGE
		STATE:			MA
		ZIP:			02139

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Cyclerion Therapeutics, Inc.
		CENTRAL INDEX KEY:			0001755237
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				831895370
		STATE OF INCORPORATION:			MA
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		301 BINNEY STREET
		CITY:			CAMBRIDGE
		STATE:			MA
		ZIP:			02142
		BUSINESS PHONE:		617-621-7722

	MAIL ADDRESS:	
		STREET 1:		301 BINNEY STREET
		CITY:			CAMBRIDGE
		STATE:			MA
		ZIP:			02142
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>form4.xml
<DESCRIPTION>FORM 4
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0306</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2021-06-24</periodOfReport>

    <issuer>
        <issuerCik>0001755237</issuerCik>
        <issuerName>Cyclerion Therapeutics, Inc.</issuerName>
        <issuerTradingSymbol>CYCN</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001298814</rptOwnerCik>
            <rptOwnerName>Fanucci Marsha</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O CYCLERION THERAPEUTICS, INC.</rptOwnerStreet1>
            <rptOwnerStreet2>245 FIRST STREET, 18TH FLOOR</rptOwnerStreet2>
            <rptOwnerCity>CAMBRIDGE</rptOwnerCity>
            <rptOwnerState>MA</rptOwnerState>
            <rptOwnerZipCode>02142</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>true</isDirector>
        </reportingOwnerRelationship>
    </reportingOwner>

    <derivativeTable>
        <derivativeTransaction>
            <securityTitle>
                <value>Stock Option (Right to Buy)</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>3.97</value>
            </conversionOrExercisePrice>
            <transactionDate>
                <value>2021-06-24</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>A</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>10000</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>0</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <exerciseDate>
                <footnoteId id="F1"/>
            </exerciseDate>
            <expirationDate>
                <value>2031-06-24</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>10000</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>10000</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeTransaction>
    </derivativeTable>

    <footnotes>
        <footnote id="F1">The options, granted pursuant to the director compensation plan, will vest in full on the first anniversary of the grant date.</footnote>
    </footnotes>

    <remarks>Exhibit 24 - Power of Attorney</remarks>

    <ownerSignature>
        <signatureName>/s/ Gary J. Simon, Attorney-in-Fact</signatureName>
        <signatureDate>2021-06-28</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>EX-24
<SEQUENCE>2
<FILENAME>brhc10026339_ex24.htm
<DESCRIPTION>EXHIBIT 24
<TEXT>
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<body bgcolor="#ffffff" style="font-family: 'Times New Roman'; font-size: 10pt; text-align: left; color: #000000;">
  <div>
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    <div>
      <div style="text-align: right; font-family: 'Times New Roman',Times,serif; font-weight: bold;">Exhibit 24</div>
      <div><br>
      </div>
      <div style="text-align: center; font-family: 'Times New Roman',Times,serif;">POWER OF ATTORNEY</div>
      <div><br>
      </div>
      <div>
        <div style="color: rgb(0, 0, 0); font-family: 'Times New Roman',Times,serif;">Know all by these presents, that the undersigned hereby constitutes and appoints each of Anjeza Gjino, Gary Simon and Sokol Malollari signing singly, as the undersigned&#8217;s
          true and lawful attorney-in-fact to:</div>
        <div><br>
        </div>
      </div>
      <div>
        <table cellspacing="0" cellpadding="0" style="font-family: 'Times New Roman'; font-size: 10pt; width: 100%; text-align: left; color: #000000;" class="DSPFListTable" id="z3abd166ab61346cc87b18581468ad320">

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              <td style="width: 36pt;"><br>
              </td>
              <td style="width: 36pt; vertical-align: top; color: rgb(0, 0, 0); font-family: 'Times New Roman',Times,serif;">(1)</td>
              <td style="width: auto; vertical-align: top;">
                <div style="color: rgb(0, 0, 0); font-family: 'Times New Roman',Times,serif;">execute for and on behalf of the undersigned, in the undersigned&#8217;s capacity as an officer and/or director of Cyclerion Therapeutics, Inc. (the &#8220;Company&#8221;), a Form
                  ID, including amendments thereto, and any other related documents necessary or appropriate to obtain from the Electronic Data Gathering and Retrieval System of the United States Securities and Exchange Commission (the &#8220;SEC&#8221;) the codes,
                  numbers and passphrases enabling the undersigned to make electronic filings with the SEC as required under the United States Securities Act of 1933, as amended, pursuant to Rule 506(b) of Regulation D promulgated thereunder Forms 3, 4 and
                  5 in accordance with Section 16(a) of the Securities Exchange Act of 1934, as amended (the &#8220;Act&#8221;), and the rules thereunder;</div>
              </td>
            </tr>

        </table>
        <div><br>
        </div>
        <table cellspacing="0" cellpadding="0" style="font-family: 'Times New Roman'; font-size: 10pt; width: 100%; text-align: left; color: #000000;" class="DSPFListTable" id="zf49dbed971f041a8ae6a49506a2b898d">

            <tr>
              <td style="width: 36pt;"><br>
              </td>
              <td style="width: 36pt; vertical-align: top; color: rgb(0, 0, 0); font-family: 'Times New Roman',Times,serif;">(2)</td>
              <td style="width: auto; vertical-align: top;">
                <div style="color: rgb(0, 0, 0); font-family: 'Times New Roman',Times,serif;">do and perform any and all acts for and on behalf of the undersigned which may be necessary or desirable to complete and execute any such Form ID, 3, 4 or 5 and
                  timely file such form with the United States Securities and Exchange Commission and any stock exchange or similar authority; and</div>
              </td>
            </tr>

        </table>
        <div><br>
        </div>
        <table cellspacing="0" cellpadding="0" style="font-family: 'Times New Roman'; font-size: 10pt; width: 100%; text-align: left; color: #000000;" class="DSPFListTable" id="z0e2cb3ea9f28457380ad49576276d0eb">

            <tr>
              <td style="width: 36pt;"><br>
              </td>
              <td style="width: 36pt; vertical-align: top; color: rgb(0, 0, 0); font-family: 'Times New Roman',Times,serif;">(3)</td>
              <td style="width: auto; vertical-align: top;">
                <div style="color: rgb(0, 0, 0); font-family: 'Times New Roman',Times,serif;">take any other action of any type whatsoever in connection with the foregoing which, in the opinion of such attorney-in-fact, may be of benefit to, in the best
                  interest of, or legally required by, the undersigned, it being understood that the documents executed by such attorney-in-fact on behalf of the undersigned pursuant to this Power of Attorney shall be in such form and shall contain such
                  terms and conditions as such attorney-in-fact may approve in such attorney-in-fact&#8217;s discretion.</div>
              </td>
            </tr>

        </table>
      </div>
      <div>
        <div><br>
        </div>
        <div style="color: rgb(0, 0, 0); font-family: 'Times New Roman',Times,serif;">The undersigned hereby grants to each attorney-in-fact full power and authority to do and perform any and every act and thing whatsoever requisite, necessary or proper to
          be done in the exercise of any of the rights and powers herein granted, as fully to all intents and purposes as the undersigned might or could do if personally present, with full power of substitution or revocation, hereby ratifying and
          confirming all the acts such attorney-in-fact shall lawfully do or cause to be done by virtue of this power of attorney and the rights and powers herein granted. The undersigned acknowledges that each of the foregoing attorneys-in-fact, in
          serving in such capacity at the request of the undersigned, is not assuming any of the undersigned&#8217;s responsibilities to comply with Section 16 of the Act.</div>
        <div><br>
        </div>
        <div style="color: rgb(0, 0, 0); font-family: 'Times New Roman',Times,serif;">This Power of Attorney shall remain in full force and effect until the undersigned is no longer required to file Forms ID, 3, 4 and 5 with respect to the undersigned&#8217;s
          holdings of and transactions in securities issued by the Company, unless earlier revoked by the undersigned in a signed writing delivered to each of the foregoing attorneys-in-fact.</div>
        <div><br>
        </div>
        <div style="color: rgb(0, 0, 0); font-family: 'Times New Roman',Times,serif;">IN WITNESS WHEREOF, the undersigned has caused this Power of Attorney to be executed as of this 29th day of April, 2021.</div>
        <div><br>
        </div>
      </div>
      <div style="margin-right: 36pt; font-family: 'Times New Roman',Times,serif;">By: /s/ Marsha Fanucci</div>
      <div><br>
      </div>
      <div style="margin-right: 36pt; font-family: 'Times New Roman',Times,serif;">Print Name: Marsha Fanucci</div>
    </div>
    <div><br>
      <div><br>
      </div>
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</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
