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License and Option Agreement - Additional Information (Details) - USD ($) $ in Thousands |  |  | 1 Months Ended | 12 Months Ended
--- | --- | --- | --- | ---
Jul. 22, 2024 | Jun. 03, 2021 | Aug. 31, 2024 | Dec. 31, 2024
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |
Option fee |  |  | $ 150,000 |
Option additional fee | $ 25,000 |  |  |
Recognized revenue related to the option fee payment and expense reimbursement |  |  |  | $ 200
Akebia Research License Agreement [Member] |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |
Up front payment received |  | $ 3,000 |  |
Amendment Akebia Research License Agreement [Member] |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |
Up front payment received |  |  |  | 1,250
Additional up front payment |  |  |  | 500
Commercialization milestone payments |  |  |  | $ 558,500

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- Definition Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Topic 808 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 1 -Subparagraph (d) -Publisher FASB -URI https://asc.fasb.org/1943274/2147479402/808-10-50-1 + Details
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