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Share-based Compensation Plans (Details) $ / shares in Units, $ in Thousands | 12 Months Ended
--- | ---
Dec. 31, 2024 USD ($) TradingDay $ / shares shares | Dec. 31, 2023 USD ($) $ / shares shares
Share-based Compensation Plans |  |
Share-based compensation | $ | $ 625 | $ 1,067
Research and development |  |
Share-based Compensation Plans |  |
Share-based compensation | $ | 91 | 421
General and administrative |  |
Share-based Compensation Plans |  |
Share-based compensation | $ | $ 534 | $ 646
Restricted Stock Awards |  |
Share-based Compensation Plans |  |
Granted (in shares) | 65,000 | 200,000
Vested (in shares) | 71,763 |
Restricted Stock Awards | Director |  |
Share-based Compensation Plans |  |
Expected period to recognize the expense | 2 years 8 months 4 days |
Unrecognized share-based compensation expense | $ | $ 400 |
Performance stock options |  |
Share-based Compensation Plans |  |
Number of shares vested | 0 | 0
Share based compensation expense | $ | $ 0 | $ 0
Employee Stock Option |  |
Share-based Compensation Plans |  |
outstanding stock options | 335,448 | 291,368
Market conditions forfeited | 11,769 |
Weighted average exercise price | $ / shares | $ 158.98 | $ 189.09
Expected period to recognize the expense | 3 years 7 months 20 days |
Weighted average grant date fair value per option share | $ / shares | $ 2.8 | $ 2.95
Total intrinsic value | $ | $ 0 | $ 0
Unrecognized share-based compensation expense | $ | $ 400 |
Granted (in shares) | 55,849 | 4,000
Market-based Stock Options |  |
Share-based Compensation Plans |  |
Threshold consecutive trading days, used as a base for measurement of vesting of stock awards | TradingDay | 30 |
outstanding stock options | 0 |
Market conditions forfeited | 7,500 |
Granted (in shares) | 0 | 0
Market-based Stock Options | Minimum |  |
Share-based Compensation Plans |  |
Expected option term (in years) | 4 years |
Market-based Stock Options | Maximum |  |
Share-based Compensation Plans |  |
Expected option term (in years) | 4 years 7 months 6 days |

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