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Commitments and contingencies - Narrative (Details) | 12 Months Ended |  |
--- | --- | --- | ---
Dec. 31, 2018 USD ($) | Dec. 31, 2017 USD ($) | Dec. 31, 2016 USD ($) | May 31, 2018 USD ($) | Jul. 31, 2017 USD ($) ft²
Operating Leased Assets [Line Items] |  |  |  |  |
Future minimum lease payments | $ 338,414 |  |  |  |
Rent expense | 238,131 | $ 214,634 | $ 202,788 |  |
Commitments due in 2019 | 122,858 |  |  |  |
Commitments due in 2020 | 64,637 |  |  |  |
Office Space Located in Maynard, Massachusetts |  |  |  |  |
Operating Leased Assets [Line Items] |  |  |  |  |
Square feet of office space | ft² |  |  |  |  | 3,558
Future minimum lease payments | 278,000 |  |  |  | $ 332,824
Commitments due in 2019 | 63,000 |  |  |  |
Panama Farm Site |  |  |  |  |
Operating Leased Assets [Line Items] |  |  |  |  |
Future minimum lease payments | 60,000 |  |  | $ 180,000 |
Commitments due in 2019 | $ 60,000 |  |  |  |

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