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Stockholders' equity - Recent Stock Issuances (Details) - USD ($) | 1 Months Ended | 12 Months Ended |
--- | --- | --- | ---
Oct. 31, 2018 | Jan. 31, 2018 | Jan. 31, 2017 | Dec. 31, 2018 | Dec. 31, 2017 | Oct. 24, 2018
New Common Shares Issued (value) |  |  |  | $ 10,616,046 | $ 24,989,257 |
New Common Shares Issued (number of shares) |  |  |  | 2,500,285 |  |
Proceeds from Warrant Exercises |  |  |  | $ 5,300,000 |  |
Common stock, par value (in dollars per share) |  |  |  | $ 0.001 | $ 0.001 |
Common Stock |  |  |  |  |  |
New Common Shares Issued (value) |  |  |  | $ 3,692 | $ 2,421 |
New Common Shares Issued (number of shares) |  |  |  | 3,692,307 | 2,421,073 |
January 2017 Equity Subscription [Member] | Common Stock | Intrexon [Member] |  |  |  |  |  |
New Common Shares Issued (value) |  |  | $ 25,000,000 |  |  |
New Common Shares Issued (number of shares) |  |  | 2,421,073 |  |  |
Shares Issued, Price Per Share |  |  | $ 10.326 |  |  |
January 2018 Public Offering [Member] |  |  |  |  |  |
Proceeds from Issuance or Sale of Equity |  | $ 10,600,000 |  |  |  |
January 2018 Public Offering [Member] | Majority Shareholder |  |  |  |  |  |
Proceeds from Issuance or Sale of Equity |  | $ 5,000,000 |  |  |  |
October 2018 Common Share Offering [Member] |  |  |  |  |  |
Proceeds from Issuance or Sale of Equity | $ 4,300,000 |  |  |  |  |
Common stock, par value (in dollars per share) |  |  |  |  |  | $ 2.00
Common Stock | January 2018 Public Offering [Member] |  |  |  |  |  |
New Common Shares Issued (number of shares) |  | 3,692,307 |  |  |  |
Common Stock | January 2018 Public Offering [Member] | Majority Shareholder |  |  |  |  |  |
New Common Shares Issued (number of shares) |  | 1,538,461 |  |  |  |
Common Stock | October 2018 Common Share Offering [Member] |  |  |  |  |  |
New Common Shares Issued (number of shares) | 2,250,461 |  |  |  |  |
Warrant [Member] |  |  |  |  |  |
New Common Shares Issued (number of shares) |  |  |  | 4,246,153 |  |
Warrant [Member] | January 2018 Public Offering [Member] |  |  |  |  |  |
New Common Shares Issued (number of shares) |  | 4,246,153 |  | 4,246,153 |  |
Warrant [Member] | January 2018 Public Offering [Member] | Majority Shareholder |  |  |  |  |  |
New Common Shares Issued (number of shares) |  | 1,538,461 |  |  |  |
Majority Shareholder | October 2018 Common Share Offering [Member] |  |  |  |  |  |
Proceeds from Issuance or Sale of Equity | $ 3,100,000 |  |  |  |  |
Majority Shareholder | Common Stock | October 2018 Common Share Offering [Member] |  |  |  |  |  |
New Common Shares Issued (number of shares) | 1,538,461 |  |  |  |  |

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