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Quarterly Financial Information (unaudited) (Tables)
 12 Months Ended
Dec. 31, 2018
Quarterly Financial Data [Abstract]  
Quarterly Financial Information
The following information has been derived from unaudited consolidated statements that, in the opinion of management, include all recurring adjustments necessary for a fair statement of such information.
 
 
Three Months Ended 2018
 
 
March 31
 
June 30
 
September 30
 
December 31
Revenue
 
$
19,097

 
$
47,898

 
$
10,938

 
$
6,585

Operating loss
 
(2,443,472
)
 
(2,784,583
)
 
(2,720,027
)
 
(2,417,714
)
Net loss
 
(2,449,787
)
 
(2,781,149
)
 
(2,727,028
)
 
(2,424,095
)
Deemed dividend
 
—

 
—

 
—

 
(1,822,873
)
Basic and diluted net loss per share attributable to common shareholders
 
$
(0.21
)
 
$
(0.22
)
 
$
(0.21
)
 
$
(0.30
)
 
 
Three Months Ended 2017
 
 
March 31
 
June 30
 
September 30
 
December 31
Revenue
 
$
—

 
$
53,278

 
$
—

 
$
—

Operating loss
 
(2,049,098
)
 
(2,087,074
)
 
(2,439,230
)
 
(2,655,756
)
Net loss
 
(2,055,743
)
 
(2,093,436
)
 
(2,446,219
)
 
(2,663,249
)
Basic and diluted net loss per share attributable to common shareholders
 
$
(0.24
)
 
$
(0.24
)
 
$
(0.28
)
 
$
(0.30
)