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Commitments and contingencies - Narrative (Details)	12 Months Ended
	Dec. 31, 2018 USD ($)	Dec. 31, 2017 USD ($)	Dec. 31, 2016 USD ($)	May 31, 2018 USD ($)	Jul. 31, 2017 USD ($) ft²
Operating Leased Assets [Line Items]
Future minimum lease payments	$ 338,414
Rent expense	238,131	$ 214,634	$ 202,788
Commitments due in 2019	122,858
Commitments due in 2020	64,637
Office Space Located in Maynard, Massachusetts
Operating Leased Assets [Line Items]
Square feet of office space | ft²					3,558
Future minimum lease payments	278,000				$ 332,824
Commitments due in 2019	63,000
Panama Farm Site
Operating Leased Assets [Line Items]
Future minimum lease payments	60,000			$ 180,000
Commitments due in 2019	$ 60,000

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Amount of required minimum rental payments for leases having an initial or remaining non-cancelable letter-terms in excess of one year.

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