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Income Taxes (Details) (USD $)
 12 Months Ended
Dec. 31, 2012
Dec. 31, 2011
Dec. 31, 2010
Income tax provision (benefit), Current portion:      
Federal $ (5,000) $ 247,000 $ (19,000)
State 3,000 3,000 2,000
Foreign 112,000 38,000 68,000
Total 110,000 288,000 51,000
Deferred tax assets:      
Federal and state loss carryforwards 30,977,000 20,196,000  
Reserves, accruals and other 341,000 685,000  
Depreciation and amortization 1,991,000 2,117,000  
Deferred stock-based compensation 3,319,000 3,061,000  
Research and development credit carryforwards 7,476,000 6,856,000  
Foreign tax and other credits 1,326,000 1,347,000  
Total deferred tax assets 45,430,000 34,262,000  
Deferred tax liabilities:      
Acquired intangible assets and other 1,652,000 1,898,000  
Less: Valuation allowance (43,778,000) (32,364,000)  
Increase (decrease) in valuation allowance during the year 11,400,000 (2,700,000)  
Valuation allowance related to stock option deductions incurred prior to January 1, 2006, the benefit of which will be credited to additional paid-in capital if they become realized 1,800,000    
Federal
      
Net operating loss carryforwards      
Net operating loss carryforwards, amount 80,600,000    
Net operating loss related to excess tax benefits from stock-based compensation that will be charged to additional paid-in capital when realized 5,500,000    
State
      
Net operating loss carryforwards      
Net operating loss carryforwards, amount 86,500,000    
Net operating loss related to excess tax benefits from stock-based compensation that will be charged to additional paid-in capital when realized $ 4,700,000