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Stock-Based Compensation (Details) (USD $)
 12 Months Ended 1 Months Ended 12 Months Ended 1 Months Ended 12 Months Ended 1 Months Ended 12 Months Ended 1 Months Ended 12 Months Ended
Dec. 31, 2012
Dec. 31, 2011
Dec. 31, 2010
Dec. 31, 2012
Options
Dec. 31, 2011
Options
Dec. 31, 2010
Options
Jun. 30, 2011
Options
Executive vice president
Dec. 31, 2012
Inducement grant options
Dec. 31, 2011
Inducement grant options
Dec. 31, 2010
Inducement grant options
Jun. 30, 2010
ESPP
Item
Dec. 31, 2012
ESPP
Dec. 31, 2011
ESPP
Jun. 30, 2010
ESPP
Maximum
Dec. 31, 2012
Plans
Options
Dec. 31, 2011
Plans
Options
Dec. 31, 2010
Plans
Options
Dec. 31, 2012
Plans
Restricted stock awards and restricted stock unit
Dec. 31, 2011
Plans
Restricted stock awards and restricted stock unit
Dec. 31, 2010
Plans
Restricted stock awards and restricted stock unit
Dec. 31, 2010
Amended 2000 Plan
Options
Dec. 31, 2012
Amended 2000 Plan
Options
Jun. 30, 2010
2010 Plan
Jun. 30, 2010
2010 Plan
Options
Dec. 31, 2012
2010 Plan
Options
Stock-Based Compensation                                                  
Number of shares outstanding               3,358,000 4,815,000 4,812,000         6,872,000 6,528,000 5,594,000         3,158,000      
Weighted-average exercise price (in dollars per share)               $ 4.29 $ 3.29 $ 2.92         $ 4.05 $ 4.48 $ 4.64         $ 4.44      
Number of shares reserved for issuance                     2,000,000                       4,000,000    
Annual increase in the share reserved for issuance (in shares)                             500,000 500,000 4,000,000       500,000   500,000    
Term of Plan                                             10 years 6 years  
Maximum annual option grants or other awards to the entity's non-employee directors (in shares)                                               40,000  
Maximum one-time grant of an option or other awards to the entity's non-employee directors (in shares)                                               120,000  
Maximum term of options granted                                                 10 years
Minimum percentage of voting rights required for applicability of a specific expiration term                                                 10.00%
Maximum expiration term of options granted                                                 5 years
Vesting period                                                 4 years
Employee Stock Purchase Plan                                                  
Number of shares reserved for issuance                     2,000,000                       4,000,000    
Maximum amount of shares that eligible employee may purchase annually (in dollars)                           $ 25,000                      
Number of offering periods                     2                            
Offering period                     6 months                            
Purchase price to be paid by participants as a percentage of price per share either at the beginning or the end of each six-month offering period, whichever is less                     85.00%                            
Shares of common stock issued under the plan                       351,000 310,000                        
Aggregate purchase price (in dollars)                       1,100,000 1,100,000                        
Shares authorized and unissued                       1,335,000     1,265,000 1,977,000 3,650,000                
Stock-based compensation expense $ 3,800,000 $ 3,800,000 $ 3,300,000                                            
Number of options grants to the new officer approved by the board of directors             675,000 350,000 400,000           1,827,000 2,201,000 1,690,000                
Period of projected requisite service over which the compensation expense is being recognized       2 years 7 months 6 days                                          
Option granted as compensation for the consulting services (in shares)             675,000 350,000 400,000           1,827,000 2,201,000 1,690,000                
Assumptions used in estimation of fair value of the share-based payment awards on the grant date                                                  
Risk-free interest rate, minimum (as a percent)       0.20% 0.20% 0.60%                                      
Risk-free interest rate, maximum (as a percent)       0.80% 1.70% 2.10%                                      
Volatility, minimum (as a percent)       59.50% 40.70% 62.50%                                      
Volatility, maximum (as a percent)       73.10% 65.40% 72.70%                                      
Expected life       4 years 4 years 4 years                                      
Dividend yield (as a percent)       0.00% 0.00% 0.00%                                      
Period for which historical volatility is considered to determine expected volatility       4 years                                          
Available for Grant                                                  
Balance at the beginning of the period (in shares)                             1,977,000 3,650,000 1,875,000                
Additional shares authorized under the Plan                             500,000 500,000 4,000,000       500,000   500,000    
Plan termination (in shares)                                 (1,502,000)                
Options cancelled prior to and upon termination of the Plan (in shares)                                 487,000                
Options granted (in shares)                             (1,827,000) (2,201,000) (1,690,000)                
Options cancelled (in shares)                             615,000 28,000                  
Options expired (in shares)                                 (20,000)                
Balance at the end of the period (in shares)                       1,335,000     1,265,000 1,977,000 3,650,000                
Number of Shares                                                  
Balance at the beginning of the period (in shares)               4,815,000 4,812,000 5,295,000         6,528,000 5,594,000 5,450,000         3,158,000      
Options cancelled prior to and upon termination of the Plan (in shares)                                 (487,000)                
Options cancelled and expired subsequent to termination of the Plan (in shares)                                 (401,000)                
Options granted (in shares)             675,000 350,000 400,000           1,827,000 2,201,000 1,690,000                
Options cancelled (in shares)               (550,000) (48,000) (108,000)         (615,000) (28,000)                  
Options exercised (in shares)               (1,257,000) (349,000) (375,000)         (266,000) (524,000) (658,000)                
Options expired (in shares)                             (602,000) (715,000)                  
Balance at the end of the period (in shares)               3,358,000 4,815,000 4,812,000         6,872,000 6,528,000 5,594,000         3,158,000      
Weighted Average Exercise Prices                                                  
Balance at the beginning of the period (in dollars per share)               $ 3.29 $ 2.92 $ 2.81         $ 4.48 $ 4.64 $ 4.37         $ 4.44      
Options cancelled prior to and upon termination of the Plan (in dollars per share)                                 $ 4.31                
Options cancelled and expired subsequent to termination of the Plan (in dollars per share)                                 $ 2.98                
Options granted (in dollars per share)               $ 3.92 $ 6.06           $ 3.19 $ 4.13 $ 4.47                
Options cancelled (in dollars per share)               $ 1.55 $ 1.54 $ 1.55         $ 3.97 $ 4.23                  
Options exercised (in dollars per share)               $ 1.55 $ 1.55 $ 1.54         $ 2.38 $ 3.34 $ 2.47                
Options expired (in dollars per share)                             $ 6.89 $ 5.45                  
Balance at the end of the period (in dollars per share)               $ 4.29 $ 3.29 $ 2.92         $ 4.05 $ 4.48 $ 4.64         $ 4.44      
Number of Shares                                                  
Non-vested shares at the beginning of the period                                   15,000 31,000 46,000          
Vested (in shares)                                   (12,000) (16,000) (15,000)          
Cancelled (in shares)                                   (3,000)              
Non-vested shares at the end of the period                                     15,000 31,000          
Weighted Average Grant-Date Fair Value                                                  
Non-vested shares at the beginning of the period (in dollars per share)                                   $ 1.60 $ 1.60 $ 1.60          
Vested (in dollars per share)                                   $ 1.62 $ 1.60 $ 1.60          
Cancelled (in dollars per share)                                   $ 1.55              
Non-vested shares at the end of the period (in dollars per share)                                     $ 1.60 $ 1.60