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CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS (USD $) In Thousands, unless otherwise specified | 9 Months Ended
--- | ---
Sep. 30, 2014 | Sep. 30, 2013
Cash flows from operating activities: |  |
Net loss | $ (23,731) | $ (18,338)
Adjustments to reconcile net loss to net cash used in operating activities: |  |
Depreciation and amortization | 313 | 565
Stock-based compensation | 3,596 | 2,800
Amortization of intangible assets | 750 | 750
Gain on sale of assets |  | (630)
Other non-cash items |  | 13
Changes in assets and liabilities: |  |
Accounts receivable | (27) | 233
Prepaid expenses and other assets | 357 | (173)
Inventory | (190) | (195)
Deferred revenue | (94) | (276)
Accounts payable | (118) | (198)
Accrued expenses and other liabilities | 433 | (2,268)
Net cash used in operating activities | (18,711) | (17,717)
Cash flows from investing activities: |  |
Purchases of property and equipment | (289) | (120)
Net proceeds from sale of assets |  | 630
Proceeds from sales and maturities of marketable securities | 32,985 | 40,967
Purchases of marketable securities | (15,859) | (53,885)
Net cash provided by investing activities | 16,837 | (12,408)
Cash flows from financing activities: |  |
Net proceeds from issuance of common stock | 2,195 | 2,024
Proceeds from the sale of common stock, net of issuance costs |  | 27,746
Net cash provided by financing activities | 2,195 | 29,770
Net increase (decrease) in cash and cash equivalents | 321 | (355)
Cash and cash equivalents at beginning of period | 4,364 | 2,529
Cash and cash equivalents at end of period | $ 4,685 | $ 2,174

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- Definition The aggregate expense charged against earnings to allocate the cost of intangible assets (nonphysical assets not used in production) in a systematic and rational manner to the periods expected to benefit from such assets. As a noncash expense, this element is added back to net income when calculating cash provided by or used in operations using the indirect method. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 28 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=31042434&loc=d3e3602-108585 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 350 -SubTopic 30 -Section 45 -Paragraph 2 -URI http://asc.fasb.org/extlink&oid=6388964&loc=d3e16225-109274 Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 350 -SubTopic 30 -Section 50 -Paragraph 2 -Subparagraph (a)(2) -URI http://asc.fasb.org/extlink&oid=26713463&loc=d3e16323-109275 + Details
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- Definition Amount of currency on hand as well as demand deposits with banks or financial institutions. Includes other kinds of accounts that have the general characteristics of demand deposits. Also includes short-term, highly liquid investments that are both readily convertible to known amounts of cash and so near their maturity that they present insignificant risk of changes in value because of changes in interest rates. Excludes cash and cash equivalents within disposal group and discontinued operation. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Glossary Cash -URI http://asc.fasb.org/extlink&oid=6506951 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Glossary Cash Equivalents -URI http://asc.fasb.org/extlink&oid=6507016 Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher SEC -Name Regulation S-X (SX) -Number 210 -Section 02 -Paragraph 1 -Article 5 Reference 4: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 210 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SX 210.5-02.1) -URI http://asc.fasb.org/extlink&oid=6877327&loc=d3e13212-122682 Reference 5: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 210 -SubTopic 10 -Section 45 -Paragraph 1 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=28358313&loc=d3e6676-107765 Reference 6: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 4 -URI http://asc.fasb.org/extlink&oid=31042434&loc=d3e3044-108585 + Details
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