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CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS (USD $) In Thousands, except Per Share data, unless otherwise specified | 3 Months Ended | 9 Months Ended
--- | --- | ---
Sep. 30, 2014 | Sep. 30, 2013 | Sep. 30, 2014 | Sep. 30, 2013
Net revenue |  |  |  |
Product | $ 437 | $ 90 | $ 1,993 | $ 211
Royalty and other | 716 | 867 | 2,241 | 3,201
Total net revenue | 1,153 | 957 | 4,234 | 3,412
Cost of net revenue | 447 | 158 | 2,046 | 254
Gross profit | 706 | 799 | 2,188 | 3,158
Operating expenses |  |  |  |
Research and development | 7,507 | 6,243 | 20,993 | 17,546
Selling, general and administrative | 1,689 | 1,595 | 4,976 | 4,678
Gain on sale of assets |  |  |  | (630)
Total operating expenses | 9,196 | 7,838 | 25,969 | 21,594
Loss from operations | (8,490) | (7,039) | (23,781) | (18,436)
Other income, net | 30 | 122 | 115 | 166
Loss before income taxes | (8,460) | (6,917) | (23,666) | (18,270)
Income tax provision | 23 | 28 | 65 | 68
Net loss | (8,483) | (6,945) | (23,731) | (18,338)
Other comprehensive income (loss), net of tax: |  |  |  |
Net unrealized gains (losses) on available-for-sale securities | (17) | 51 | (20) | (19)
Comprehensive loss | $ (8,500) | $ (6,894) | $ (23,751) | $ (18,357)
Net loss per share |  |  |  |
Basic and diluted (in dollars per share) | $ (0.17) | $ (0.14) | $ (0.48) | $ (0.42)
Shares used in computing net loss per share |  |  |  |
Basic and diluted (in shares) | 49,634 | 48,164 | 49,441 | 44,173

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