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CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($)
$ in Thousands
 9 Months Ended
Sep. 30, 2015
Sep. 30, 2014
Cash flows from operating activities:    
Net loss $ (24,976) $ (23,731)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 466 313
Stock-based compensation 2,864 3,596
Amortization of intangible assets 293 750
Changes in assets and liabilities:    
Accounts receivable (249) (27)
Inventories (383) (190)
Prepaid expenses and other assets (624) 357
Accounts payable (238) (118)
Accrued expenses and other liabilities (275) 339
Net cash used in operating activities (23,122) (18,711)
Cash flows from investing activities:    
Purchases of property and equipment (369) (289)
Proceeds from sales and maturities of marketable securities 34,172 32,985
Purchases of marketable securities (35,347) (15,859)
Net cash (used in) provided by investing activities (1,544) 16,837
Cash flows from financing activities:    
Proceeds from the sale of common stock, net of issuance costs 21,368  
Proceeds from issuance of common stock 1,773 2,195
Net cash provided by financing activities 23,141 2,195
Net increase (decrease) in cash and cash equivalents (1,525) 321
Cash and cash equivalents at beginning of period 3,110 4,364
Cash and cash equivalents at end of period $ 1,585 $ 4,685