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v3.3.1.900

CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($) $ in Thousands | 12 Months Ended
--- | ---
Dec. 31, 2015 | Dec. 31, 2014 | Dec. 31, 2013
Cash flows from operating activities: |  |  |
Net loss | $ (31,483) | $ (32,682) | $ (24,794)
Adjustments to reconcile net loss to net cash used in operating activities: |  |  |
Depreciation and amortization | 607 | 449 | 679
Amortization of intangible assets | 321 | 1,000 | 999
Stock-based compensation | 3,650 | 4,591 | 3,698
Gain on sale of assets |  |  | (630)
Other non-cash items |  |  | 7
Changes in assets and liabilities: |  |  |
Accounts receivable | (552) | (29) | 139
Inventories | (716) | (314) | (315)
Prepaid expenses and other assets | 104 | 405 | 1
Accounts payable | 261 | (23) | (125)
Accrued expenses and other liabilities | 334 | 296 | (2,304)
Net cash used in operating activities | (27,474) | (26,307) | (22,645)
Cash flows from investing activities: |  |  |
Purchases of property and equipment | (1,202) | (596) | (154)
Net proceeds from sale of assets |  |  | 630
Proceeds from sales and maturities of marketable securities | 44,953 | 39,270 | 49,267
Purchases of marketable securities | (36,873) | (15,859) | (57,202)
Net cash provided by (used in) investing activities | 6,878 | 22,815 | (7,459)
Cash flows from financing activities: |  |  |
Proceeds from the sale of common stock, net of issuance costs | 21,368 |  | 27,746
Net proceeds from issuance of common stock | 1,772 | 2,238 | 4,193
Payments on capital lease obligations | (14) |  |
Net cash provided by financing activities | 23,126 | 2,238 | 31,939
Net increase (decrease) in cash and cash equivalents | 2,530 | (1,254) | 1,835
Cash and cash equivalents at beginning of period | 3,110 | 4,364 | 2,529
Cash and cash equivalents at end of period | 5,640 | 3,110 | 4,364
Supplemental disclosure: |  |  |
Cash paid for income taxes | $ 56 | $ 111 | $ 92

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