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Income Taxes (Tables) | 12 Months Ended
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Dec. 31, 2015
Income Taxes |
Schedule of income tax provision (benefit) | The income tax provision consisted of the following (in thousands):
|  | Year Ended December 31, |  |
|  | 2015 |  | 2014 |  | 2013 |  |
Current portion: |  |  |  |  |  |  |  |  |  |  |
Federal |  | $ | — |  | $ | — |  | $ | — |  |
State |  |  | 3 |  |  | 3 |  |  | 2 |  |
Foreign |  |  | 83 |  |  | 104 |  |  | 69 |  |
|  | $ | 86 |  | $ | 107 |  | $ | 71 |  |
Schedule of significant components of the Company's deferred tax assets and liabilities | Significant components of the Company's deferred tax assets and liabilities were (in thousands):
|  | December 31, |
|  | 2015 |  | 2014 |
Deferred tax assets: |  |  |  |  |  |  |
Federal and state loss carryforwards |  | $ | 60,831 |  | $ | 50,057 |
Reserves, accruals and other |  |  | 761 |  |  | 587 |
Depreciation and amortization |  |  | 1,304 |  |  | 1,497 |
Deferred stock-based compensation |  |  | 4,504 |  |  | 3,589 |
Research and development credit carryforwards |  |  | 12,886 |  |  | 11,351 |
Foreign tax and other credits |  |  | 1,131 |  |  | 1,241 |
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
Total deferred tax assets |  |  | 81,417 |  |  | 68,322 |
Deferred tax liabilities: |  |  |  |  |  |  |
Acquired intangible assets and other |  |  | 1,781 |  |  | 1,537 |
Less: Valuation allowance |  |  | (79,636 | ) |  | (66,785 | )
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
Net deferred tax assets |  | $ | — |  | $ | — |
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
Schedule of reconciliation of income taxes provided at the federal statutory rate (35%) to actual income tax provision (benefit) | A reconciliation of income taxes provided at the federal statutory rate (35%) to the actual income tax provision follows (in thousands):
|  | Year Ended December 31, |
|  | 2015 |  | 2014 |  | 2013 |
Income tax benefit computed at U.S. statutory rate |  | $ | (10,989 | ) | $ | (11,401 | ) | $ | (8,653 | )
State income tax (net of federal benefit) |  |  | 3 |  |  | 3 |  |  | 2 |
Foreign income tax at rate different from U.S. statutory rate |  |  | (15 | ) |  | (12 | ) |  | (11 | )
Research and development credits |  |  | (1,580 | ) |  | (1,614 | ) |  | (1,196 | )
Stock-based compensation |  |  | 123 |  |  | 130 |  |  | 91 |
Amortization of intangible assets |  |  | (100 | ) |  | (100 | ) |  | (100 | )
Valuation allowance changes affecting tax provision |  |  | 12,588 |  |  | 13,027 |  |  | 9,915 |
Other |  |  | 56 |  |  | 74 |  |  | 23 |
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
Income tax provision |  | $ | 86 |  | $ | 107 |  | $ | 71 |
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
Schedule of domestic and foreign components of (loss) income before income tax provision | The domestic and foreign components of (loss) income before income tax provision were (in thousands):
|  | Year Ended December 31, |
|  | 2015 |  | 2014 |  | 2013 |
U.S. |  | $ | (31,580 | ) | $ | (32,735 | ) | $ | (24,906 | )
Non-U.S. |  |  | 183 |  |  | 160 |  |  | 183 |
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
|  | $ | (31,397 | ) | $ | (32,575 | ) | $ | (24,723 | )
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​

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- Definition Tabular disclosure of the components of income tax expense attributable to continuing operations for each year presented including, but not limited to: current tax expense (benefit), deferred tax expense (benefit), investment tax credits, government grants, the benefits of operating loss carryforwards, tax expense that results from allocating certain tax benefits either directly to contributed capital or to reduce goodwill or other noncurrent intangible assets of an acquired entity, adjustments of a deferred tax liability or asset for enacted changes in tax laws or rates or a change in the tax status of the entity, and adjustments of the beginning-of-the-year balances of a valuation allowance because of a change in circumstances that causes a change in judgment about the realizability of the related deferred tax asset in future years. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 740 -SubTopic 10 -Section 50 -Paragraph 9 -URI http://asc.fasb.org/extlink&oid=6907707&loc=d3e32639-109319 + Details
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- Definition Tabular disclosure of the components of net deferred tax asset or liability recognized in an entity's statement of financial position, including the following: the total of all deferred tax liabilities, the total of all deferred tax assets, the total valuation allowance recognized for deferred tax assets. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 740 -SubTopic 10 -Section 50 -Paragraph 2 -URI http://asc.fasb.org/extlink&oid=6907707&loc=d3e32537-109319 + Details
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- Definition Tabular disclosure of the reconciliation using percentage or dollar amounts of the reported amount of income tax expense attributable to continuing operations for the year to the amount of income tax expense that would result from applying domestic federal statutory tax rates to pretax income from continuing operations. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 740 -SubTopic 10 -Section 50 -Paragraph 12 -URI http://asc.fasb.org/extlink&oid=6907707&loc=d3e32687-109319 + Details
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