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Income Taxes (Tables)

12 Months Ended

Dec. 31, 2015

Income Taxes

Schedule of income tax provision (benefit)

        The income tax provision consisted of the following (in thousands):

		Year Ended December 31,
		2015			2014			2013
Current portion:
Federal		$	—		$	—		$	—
State			3			3			2
Foreign			83			104			69
		$	86		$	107		$	71

Schedule of significant components of the Company's deferred tax assets and liabilities

        Significant components of the Company's deferred tax assets and liabilities were (in thousands):

		December 31,
		2015			2014
Deferred tax assets:
Federal and state loss carryforwards		$	60,831		$	50,057
Reserves, accruals and other			761			587
Depreciation and amortization			1,304			1,497
Deferred stock-based compensation			4,504			3,589
Research and development credit carryforwards			12,886			11,351
Foreign tax and other credits			1,131			1,241
​	​	​	​	​	​	​	​
Total deferred tax assets			81,417			68,322
Deferred tax liabilities:
Acquired intangible assets and other			1,781			1,537
Less: Valuation allowance			(79,636	)		(66,785	)
​	​	​	​	​	​	​	​
Net deferred tax assets		$	—		$	—
​	​	​	​	​	​	​	​
​	​	​	​	​	​	​	​

Schedule of reconciliation of income taxes provided at the federal statutory rate (35%) to actual income tax provision (benefit)

        A reconciliation of income taxes provided at the federal statutory rate (35%) to the actual income tax provision follows (in thousands):

		Year Ended December 31,
		2015			2014			2013
Income tax benefit computed at U.S. statutory rate		$	(10,989	)	$	(11,401	)	$	(8,653	)
State income tax (net of federal benefit)			3			3			2
Foreign income tax at rate different from U.S. statutory rate			(15	)		(12	)		(11	)
Research and development credits			(1,580	)		(1,614	)		(1,196	)
Stock-based compensation			123			130			91
Amortization of intangible assets			(100	)		(100	)		(100	)
Valuation allowance changes affecting tax provision			12,588			13,027			9,915
Other			56			74			23
​	​	​	​	​	​	​	​	​	​	​
Income tax provision		$	86		$	107		$	71
​	​	​	​	​	​	​	​	​	​	​
​	​	​	​	​	​	​	​	​	​	​

Schedule of domestic and foreign components of (loss) income before income tax provision

        The domestic and foreign components of (loss) income before income tax provision were (in thousands):

		Year Ended December 31,
		2015			2014			2013
U.S.		$	(31,580	)	$	(32,735	)	$	(24,906	)
Non-U.S.			183			160			183
​	​	​	​	​	​	​	​	​	​	​
		$	(31,397	)	$	(32,575	)	$	(24,723	)
​	​	​	​	​	​	​	​	​	​	​
​	​	​	​	​	​	​	​	​	​	​

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Tabular disclosure of the components of income tax expense attributable to continuing operations for each year presented including, but not limited to: current tax expense (benefit), deferred tax expense (benefit), investment tax credits, government grants, the benefits of operating loss carryforwards, tax expense that results from allocating certain tax benefits either directly to contributed capital or to reduce goodwill or other noncurrent intangible assets of an acquired entity, adjustments of a deferred tax liability or asset for enacted changes in tax laws or rates or a change in the tax status of the entity, and adjustments of the beginning-of-the-year balances of a valuation allowance because of a change in circumstances that causes a change in judgment about the realizability of the related deferred tax asset in future years.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 740
-SubTopic 10
-Section 50
-Paragraph 9
-URI http://asc.fasb.org/extlink&oid=6907707&loc=d3e32639-109319

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Tabular disclosure of the components of net deferred tax asset or liability recognized in an entity's statement of financial position, including the following: the total of all deferred tax liabilities, the total of all deferred tax assets, the total valuation allowance recognized for deferred tax assets.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 740
-SubTopic 10
-Section 50
-Paragraph 2
-URI http://asc.fasb.org/extlink&oid=6907707&loc=d3e32537-109319

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Tabular disclosure of the reconciliation using percentage or dollar amounts of the reported amount of income tax expense attributable to continuing operations for the year to the amount of income tax expense that would result from applying domestic federal statutory tax rates to pretax income from continuing operations.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 740
-SubTopic 10
-Section 50
-Paragraph 12
-URI http://asc.fasb.org/extlink&oid=6907707&loc=d3e32687-109319

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Tabular disclosure of income before income tax between domestic and foreign jurisdictions.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 235
-SubTopic 10
-Section S99
-Paragraph 1
-Subparagraph (SX 210.4-08.(h)(1)(i))
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