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Income Taxes - Current/Deferred (Details) - USD ($)
$ in Thousands
 12 Months Ended
Dec. 31, 2015
Dec. 31, 2014
Dec. 31, 2013
Income tax provision, Current portion:      
State $ 3 $ 3 $ 2
Foreign 83 104 69
Income tax provision 86 107 $ 71
Deferred tax assets:      
Federal and state loss carryforwards 60,831 50,057  
Reserves, accruals and other 761 587  
Depreciation and amortization 1,304 1,497  
Deferred stock-based compensation 4,504 3,589  
Research and development credit carryforwards 12,886 11,351  
Foreign tax and other credits 1,131 1,241  
Total deferred tax assets 81,417 68,322  
Deferred tax liabilities:      
Acquired intangible assets and other 1,781 1,537  
Less: Valuation allowance (79,636) (66,785)  
Increase in valuation allowance during the year 12,900 $ 12,100  
Federal      
Net operating loss carryforwards      
Net operating loss carryforwards, amount 162,800    
Net operating loss related to excess tax benefits from stock-based compensation that will be charged to additional paid-in capital when realized 5,700    
State      
Net operating loss carryforwards      
Net operating loss carryforwards, amount 106,800    
Net operating loss related to excess tax benefits from stock-based compensation that will be charged to additional paid-in capital when realized $ 4,800