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CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($)
$ in Thousands
 6 Months Ended
Jun. 30, 2016
Jun. 30, 2015
Cash flows from operating activities:    
Net loss $ (12,869) $ (14,871)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 534 287
Stock-based compensation 1,150 2,044
Amortization of intangible assets 55 265
Amortization of debt issuance costs 13  
Accrued interest 233  
Net loss on disposal of assets 4  
Changes in assets and liabilities:    
Accounts receivable (333) (243)
Inventories 228 (379)
Prepaid expenses and other assets 281 14
Accounts payable (361) (54)
Accrued expenses and other liabilities (45) (130)
Net cash used in operating activities (11,110) (13,067)
Cash flows from investing activities:    
Purchases of property and equipment (612) (131)
Proceeds from sales and maturities of marketable securities 29,939 20,741
Purchases of marketable securities (20,868) (27,726)
Net cash provided by (used in) investing activities 8,459 (7,116)
Cash flows from financing activities:    
Proceeds from the sale of common stock, net of issuance costs   21,368
Proceeds from issuance of common stock 195 1,307
Proceeds from the issuance of notes payable, net of issuance costs 7,879  
Payments on capital lease obligations (83)  
Net cash provided by financing activities 7,991 22,675
Net increase in cash and cash equivalents 5,340 2,492
Cash and cash equivalents at beginning of period 5,640 3,110
Cash and cash equivalents at end of period $ 10,980 $ 5,602