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CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS - USD ($) shares in Thousands, $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2016	Sep. 30, 2015	Sep. 30, 2016	Sep. 30, 2015
Net revenue
Product	$ 1,205	$ 565	$ 3,612	$ 1,288
Royalty and other	368	457	1,045	1,504
Total net revenue	1,573	1,022	4,657	2,792
Cost of net revenue	658	793	2,484	1,593
Gross profit	915	229	2,173	1,199
Operating expenses
Research and development	3,927	8,793	14,043	21,475
Selling, general and administrative	1,450	1,547	4,543	4,711
Restructuring charges			676
Total operating expenses	5,377	10,340	19,262	26,186
Loss from operations	(4,462)	(10,111)	(17,089)	(24,987)
Interest expense	(217)		(464)
Other income, net	(2)	19	43	71
Loss before income taxes	(4,681)	(10,092)	(17,510)	(24,916)
Income tax provision	20	13	60	60
Net loss	(4,701)	(10,105)	(17,570)	(24,976)
Other comprehensive income (loss), net of tax:
Net unrealized gains (losses) on available-for-sale securities	(1)	6	15	7
Comprehensive loss	$ (4,702)	$ (10,099)	$ (17,555)	$ (24,969)
Net loss per share
Basic and diluted (in dollars per share)	$ (0.07)	$ (0.15)	$ (0.27)	$ (0.41)
Shares used in computing net loss per share
Basic and diluted (in shares)	66,091	65,317	65,918	61,486

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