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CONSOLIDATED STATEMENTS OF STOCKHOLDERS' EQUITY - USD ($)
shares in Thousands, $ in Thousands
Common Stock
Additional Paid-In Capital
Accumulated Other Comprehensive Income (Loss)
Accumulated Deficit
Total
Balance at Dec. 31, 2013 $ 5 $ 193,207 $ 13 $ (117,807) $ 75,418
Balance (in shares) at Dec. 31, 2013 4,889        
Increase (Decrease) in Stockholders' Equity          
Issuance of common stock for exercise of options, employee stock purchase plan and release of awards   2,236     2,236
Issuance of common stock for exercise of options, employee stock purchase plan and release of awards (in shares) 90        
Stock-based compensation   4,591     4,591
Change in unrealized gain (loss) on available-for-sale investments     (23)   (23)
Net loss       (32,682) (32,682)
Balance at Dec. 31, 2014 $ 5 200,034 (10) (150,489) 49,540
Balance (in shares) at Dec. 31, 2014 4,979        
Increase (Decrease) in Stockholders' Equity          
Issuance of common stock for exercise of options, employee stock purchase plan and release of awards   1,772     1,772
Issuance of common stock for exercise of options, employee stock purchase plan and release of awards (in shares) 133        
Issuance of common stock, net of costs of $1,632 $ 2 21,366     21,368
Issuance of common stock, net of costs (in shares) 1,437        
Stock-based compensation   3,650     3,650
Change in unrealized gain (loss) on available-for-sale investments     (6)   (6)
Net loss       (31,483) (31,483)
Balance at Dec. 31, 2015 $ 7 226,822 (16) (181,972) $ 44,841
Balance (in shares) at Dec. 31, 2015 6,549       6,549
Increase (Decrease) in Stockholders' Equity          
Issuance of common stock for exercise of options, employee stock purchase plan and release of awards   364     $ 364
Issuance of common stock for exercise of options, employee stock purchase plan and release of awards (in shares) 81        
Stock-based compensation   2,155     2,155
Change in unrealized gain (loss) on available-for-sale investments     $ 16   16
Net loss       (32,048) (32,048)
Balance at Dec. 31, 2016 $ 7 $ 229,341   $ (214,020) $ 15,328
Balance (in shares) at Dec. 31, 2016 6,630       6,630