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CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($)
$ in Thousands
 6 Months Ended
Jun. 30, 2017
Jun. 30, 2016
Cash flows from operating activities:    
Net loss $ (8,399) $ (12,869)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 389 534
Stock-based compensation 356 1,150
Amortization of intangible assets 56 55
Amortization of debt issuance costs 22 13
Accrued interest 430 233
Loss on disposal of assets   4
Changes in assets and liabilities:    
Accounts receivable 37 (333)
Inventories 403 228
Prepaid expenses and other assets (653) 281
Accounts payable (407) (361)
Deferred revenue and other liabilities 763 (45)
Net cash used in operating activities (7,003) (11,110)
Cash flows from investing activities:    
Purchases of property and equipment   (612)
Proceeds from sales and maturities of marketable securities 2,604 29,939
Purchases of marketable securities (1,602) (20,868)
Net cash provided by investing activities 1,002 8,459
Cash flows from financing activities:    
Net proceeds from issuance of common stock (22) 195
Proceeds from the issuance of notes payable, net of issuance costs   7,879
Payments on capital lease obligations   (83)
Net cash provided by (used in) financing activities (22) 7,991
Net increase (decrease) in cash and cash equivalents (6,023) 5,340
Cash and cash equivalents at beginning of period 8,766 5,640
Cash and cash equivalents at end of period 2,743 $ 10,980
Supplemental disclosure:    
Issuance of convertible notes in settlement of accrued interest $ 420