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CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS - USD ($) shares in Thousands, $ in Thousands | 3 Months Ended | 9 Months Ended
--- | --- | ---
Sep. 30, 2017 | Sep. 30, 2016 | Sep. 30, 2017 | Sep. 30, 2016
Net revenue |  |  |  |
Product | $ 2,231 | $ 1,205 | $ 4,297 | $ 3,612
Royalty and other | 222 | 368 | 752 | 1,045
Total net revenue | 2,453 | 1,573 | 5,049 | 4,657
Cost of net revenue | 1,256 | 658 | 2,590 | 2,484
Gross profit | 1,197 | 915 | 2,459 | 2,173
Operating expenses |  |  |  |
Research and development | 1,436 | 3,927 | 7,234 | 14,043
Selling, general and administrative | 1,244 | 1,450 | 3,659 | 4,543
Restructuring charges | 50 |  | 1,052 | 676
Total operating expenses | 2,730 | 5,377 | 11,945 | 19,262
Loss from operations | (1,533) | (4,462) | (9,486) | (17,089)
Interest expense | 238 | 217 | 685 | 464
Other income / (expense), net | 32 | (2) | 45 | 43
Loss before income taxes | (1,739) | (4,681) | (10,126) | (17,510)
Income tax provision | 4 | 20 | 16 | 60
Net loss | (1,743) | (4,701) | (10,142) | (17,570)
Other comprehensive income, net of tax: |  |  |  |
Net unrealized gains / (losses) on available-for-sale securities |  | (1) |  | 15
Comprehensive loss | $ (1,743) | $ (4,702) | $ (10,142) | $ (17,555)
Net loss per share |  |  |  |
Basic and diluted | $ (0.22) | $ (0.71) | $ (1.43) | $ (2.66)
Shares used in computing net loss per share |  |  |  |
Basic and diluted | 7,938 | 6,609 | 7,092 | 6,592

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