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Stock-Based Compensation (Tables) | 9 Months Ended | 12 Months Ended
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Sep. 30, 2017 | Dec. 31, 2016
Stock-Based Compensation |  |
Schedule of assumptions used in estimation of fair value of the share-based payment awards on the grant date |
| Nine Months Ended |
| September 30, |
| 2017 |  | 2016 |
Risk-free interest rate | 1.6% |  | 1.0% - 1.2% |
Volatility | 70.2% |  | 61.4% - 63.8% |
Expected life (years) | 4.0 |  | 4.0 - 5.0 |
Dividend yield | 0% |  | 0% |
|  | Year Ended December 31,
Employee stock options: |  | 2016 |  | 2015 |  | 2014
Risk-free interest rate |  | 1% - 2.1% |  | 0.6% -1.7% |  | 1.3% - 1.7%
Volatility |  | 61.4% - 65.0% |  | 55.7% - 59.3% |  | 53.7% - 57.5%
Expected life (years) |  | 3.0 - 5.0 |  | 3.0 - 5.0 |  | 4.0 - 5.0
Dividend yield |  | 0% |  | 0% |  | 0%
Summary of option and RSU activity under Amended and Restated 2000 Stock Option and Equity Incentive Plan and Amended and Restated 2010 Equity Incentive Plan | A summary of the option and RSU activity under the Company’s Amended and Restated 2010 Equity Incentive Plan (the Plan) is presented below (in thousands, except exercise price):
|  |  |  | Options outstanding |
|  |  |  |  |  | Weighted |
|  | Shares |  |  |  | Average |
|  | Available |  | Number of |  | Exercise |
|  | for Grant |  | Shares |  | Prices |
Balance at January 1, 2017 |  | 114 |  | 522 |  | $ | 13.88 |
Additional shares authorized under the Plan |  | 50 |  | — |  |  | — |
RSUs cancelled and returned to the Plan |  | 5 |  | — |  |  | — |
Options granted |  | (1) |  | 1 |  | $ | 2.36 |
Options cancelled and returned to the Plan |  | 15 |  | (15) |  | $ | 6.94 |
Balance at March 31, 2017 |  | 183 |  | 508 |  | $ | 14.06 |
RSUs cancelled and returned to Plan |  | 37 |  | — |  |  | — |
Options cancelled and returned to Plan |  | 172 |  | (172) |  | $ | 10.20 |
Balance at June 30, 2017 |  | 392 |  | 336 |  | $ | 16.04 |
RSUs granted |  | (407) |  | — |  |  | — |
RSUs cancelled and returned to Plan |  | 8 |  | — |  |  | — |
Options cancelled and returned to Plan |  | 88 |  | (88) |  | $ | 14.83 |
Balance at September 30, 2017 |  | 81 |  | 248 |  | $ | 16.47 |
| A summary of option activity under the Plans is presented below (in thousands, except exercise price):
|  |  |  | Options outstanding |
|  |  |  |  |  | Weighted |
|  | Shares |  |  |  | Average |
|  | Available |  | Number of |  | Exercise |
|  | for Grant |  | Shares |  | Prices |
Balance at January 1, 2014 |  | 42 |  | 672 |  | $ | 38.64 |
Additional shares authorized under the Amended 2010 Plan |  | 200 |  | — |  |  | — |
Restricted stock units granted |  | (50) |  | — |  |  | — |
Options granted |  | (17) |  | 17 |  | $ | 35.34 |
Options cancelled and returned to Plan |  | 49 |  | (49) |  | $ | 43.08 |
Options exercised |  | — |  | (41) |  | $ | 30.64 |
Options expired |  | (48) |  | — |  | $ | 43.20 |
Balance at December 31, 2014 |  | 176 |  | 599 |  | $ | 38.73 |
Additional shares authorized under the Amended 2010 Plan |  | 50 |  | — |  |  | — |
Restricted stock units cancelled and returned to Plan |  | 2 |  | — |  |  | — |
Options granted |  | (154) |  | 154 |  | $ | 20.22 |
Options cancelled and returned to Plan |  | 70 |  | (70) |  | $ | 35.23 |
Options exercised |  | — |  | (8) |  | $ | 16.37 |
Options expired |  | (38) |  | — |  | $ | 32.00 |
Balance at December 31, 2015 |  | 106 |  | 675 |  | $ | 35.14 |
Additional shares authorized under the Amended 2010 Plan |  | 50 |  | — |  |  | — |
Restricted stock units granted |  | (144) |  | — |  |  | — |
Restricted stock units cancelled and returned to Plan |  | 7 |  | — |  |  | — |
Options granted |  | (384) |  | 384 |  | $ | 6.96 |
Options cancelled and returned to Plan |  | 479 |  | (479) |  | $ | 35.64 |
Options cancelled and expired |  | — |  | (58) |  | $ | 44.80 |
Balance at December 31, 2016 |  | 114 |  | 522 |  | $ | 13.88 |
Summary of the inducement grant option activity |  | A summary of the inducement grant option activity is presented below (in thousands, except exercise price):
|  | Options Outstanding |
|  |  |  | Weighted |
|  |  |  | Average |
|  | Number of |  | Exercise |
|  | Shares |  | Prices |
Balance at January 1, 2014 |  | 318 |  | $ | 44.23 |
Granted |  | 41 |  | $ | 36.80 |
Exercised |  | (7) |  | $ | 25.87 |
Expired |  | (129) |  | $ | 55.75 |
Balance at December 31, 2014 |  | 223 |  | $ | 36.78 |
Exercised |  | (52) |  | $ | 15.48 |
Expired |  | (7) |  | $ | 31.79 |
Balance at December 31, 2015 |  | 164 |  | $ | 43.74 |
Cancelled |  | (164) |  | $ | 43.74 |
Balance at December 31, 2016 |  | — |  | $ | — |
Summary of RSU activity under the Plans | A summary of RSU activity under the Plan is presented below (in thousands, except for fair value):
|  |  |  | Weighted |
|  |  |  | Average |
|  | Number of |  | Grant-Date |
|  | Shares |  | Fair Value |
Non-vested shares at January 1, 2017 |  | 148 |  | $ | 8.13 |
Vested |  | (54) |  | $ | 11.64 |
Cancelled |  | (5) |  | $ | 5.30 |
Non-vested shares at March 31, 2017 |  | 89 |  | $ | 6.16 |
Cancelled |  | (37) |  | $ | 5.75 |
Non-vested shares at June 30, 2017 |  | 52 |  | $ | 6.46 |
Granted |  | 407 |  | $ | 0.93 |
Vested |  | (66) |  | $ | 0.95 |
Cancelled |  | (8) |  | $ | 5.30 |
Non-vested shares at September 30, 2017 |  | 385 |  | $ | 1.58 |
| A summary of restricted stock unit activity under the Plans is presented below (in thousands, except fair value):
|  |  |  | Weighted |
|  |  |  | Average |
|  | Number of |  | Grant-Date |
|  | Shares |  | Fair Value |
Non-vested shares at January 1, 2014 |  | 2 |  | $ | 44.60 |
Granted |  | 50 |  | $ | 46.11 |
Vested |  | (13) |  | $ | 45.83 |
Cancelled |  | — |  | $ | 46.20 |
Non-vested shares at December 31, 2014 |  | 39 |  | $ | 46.11 |
Vested |  | (13) |  | $ | 45.97 |
Cancelled |  | (2) |  | $ | 46.20 |
Non-vested shares at December 31, 2015 |  | 24 |  | $ | 46.17 |
Granted |  | 144 |  | $ | 5.30 |
Vested |  | (12) |  | $ | 46.06 |
Cancelled |  | (8) |  | $ | 15.67 |
Non-vested shares at December 31, 2016 |  | 148 |  | $ | 8.13 |
Summary of significant ranges of outstanding and exercisable options | The following table summarizes significant ranges of outstanding and exercisable options as of September 30, 2017 (in thousands, except contractual life and exercise price):
|  | Options Outstanding |  | Options Exercisable |  |  |  |
|  |  |  | Weighted |  |  |  |  |  |  |  |  |  |  |  |
|  |  |  | Average |  |  |  |  |  |  |  |  |  |  |  |
|  |  |  | Remaining |  | Weighted |  |  |  | Weighted |  |  |  |
|  |  |  | Contractual |  | Average |  |  |  | Average |  | Aggregate |
|  | Number |  | Life |  | Exercise |  | Number |  | Exercise |  | Intrinsic |
Range of Exercise Price |  | Outstanding |  | (in Years) |  | Price |  | Exercisable |  | Price |  | value |
$2.36 - $7.19 |  | 19 |  | 6.44 |  | $ | 5.07 |  | 12 |  | $ | 5.30 |  |  |  |
$7.20 - $16.99 |  | 122 |  | 8.35 |  | $ | 7.20 |  | 49 |  | $ | 7.20 |  |  |  |
$17.00 - $20.49 |  | 4 |  | 3.79 |  | $ | 17.00 |  | 4 |  | $ | 17.00 |  |  |  |
$20.50 - $30.89 |  | 45 |  | 7.42 |  | $ | 20.50 |  | 39 |  | $ | 20.50 |  |  |  |
$30.90 - $41.89 |  | 41 |  | 0.61 |  | $ | 36.44 |  | 41 |  | $ | 33.41 |  |  |  |
$41.90 - $46.20 |  | 17 |  | 4.16 |  | $ | 44.01 |  | 17 |  | $ | 44.01 |  |  |  |
$2.36 - $46.20 |  | 248 |  | 6.40 |  | $ | 16.47 |  | 162 |  | $ | 21.34 |  | $ | — |
Vested and expected to vest |  | 240 |  | 6.32 |  | $ | 16.77 |  |  |  |  |  |  | $ | — |
Exercisable |  | 162 |  | 5.11 |  | $ | 21.34 |  |  |  |  |  |  | $ | — |
| The following table summarizes significant ranges of outstanding and exercisable options as of December 31, 2016 (in thousands, except contractual life and exercise price):
|  | Options Outstanding |  | Options Exercisable |  |  |  |
|  |  |  | Weighted |  |  |  |  |  |  |  |  |  |  |  |
|  |  |  | Average |  |  |  |  |  |  |  |  |  |  |  |
|  |  |  | Remaining |  | Weighted |  |  |  | Weighted |  |  |  |
|  |  |  | Contractual |  | Average |  |  |  | Average |  | Aggregate |
|  | Number |  | Life |  | Exercise |  | Number |  | Exercise |  | Intrinsic |
Range of Exercise Price |  | Outstanding |  | (in Years) |  | Price |  | Exercisable |  | Price |  | value |
$3.80 - $7.19 |  | 45 |  | 8.68 |  | $ | 5.12 |  | 8 |  | $ | 5.30 |  |  |  |
$7.20 - $16.99 |  | 325 |  | 9.39 |  | $ | 7.20 |  | 36 |  | $ | 7.20 |  |  |  |
$17.00 - $30.99 |  | 84 |  | 6.33 |  | $ | 22.39 |  | 66 |  | $ | 22.92 |  |  |  |
$31-00 - $54.29 |  | 58 |  | 2.72 |  | $ | 38.41 |  | 57 |  | $ | 38.32 |  |  |  |
$54.30 - $61.09 |  | 6 |  | 0.50 |  | $ | 54.30 |  | 6 |  | $ | 54.30 |  |  |  |
$61.10 - $61.10 |  | 4 |  | 0.32 |  | $ | 61.10 |  | 4 |  | $ | 61.10 |  |  |  |
$3.80 - $61.10 |  | 522 |  | 7.82 |  | $ | 13.88 |  | 177 |  | $ | 25.83 |  | $ | — |
Vested and expected to vest |  | 522 |  | 7.82 |  | $ | 14.34 |  |  |  |  |  |  | $ | — |
Exercisable |  | 177 |  | 5.38 |  | $ | 25.83 |  |  |  |  |  |  | $ | — |

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