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Income Taxes - Significant Components of Deferred Tax Assets and Liabilities (Details) - USD ($) $ in Thousands | Dec. 31, 2018 | Dec. 31, 2017
--- | --- | ---
Deferred tax assets: |  |
Federal and state loss carryforwards | $ 681 | $ 49,533
Reserves, accruals and other | 230 | 391
Depreciation and amortization | 1,901 | 1,100
Deferred stock-based compensation | 2,571 | 2,483
Research and development credit carryforwards | 6,537 | 15,487
Foreign tax and other credits | 242 | 513
Total deferred tax assets | 12,162 | 69,507
Deferred tax liabilities: |  |
Acquired intangible assets and other |  | 408
Less: Valuation allowance | (11,920) | (68,857)
Net deferred tax assets | $ 242 | $ 242

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