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CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS - USD ($)
shares in Thousands, $ in Thousands
 12 Months Ended
Dec. 31, 2018
Dec. 31, 2017
Dec. 31, 2016
Net revenue      
Total net revenue $ 16,600 $ 8,842 $ 6,024
Cost of net revenue 6,346 4,694 3,075
Gross profit 10,254 4,148 2,949
Operating expenses      
Research and development 4,129 8,158 18,086
Selling, general and administrative 4,095 4,702 5,693
Impairment of goodwill 12,856   9,858
Restructuring charges   1,321 676
Total operating expenses 21,080 14,181 34,313
Loss from operations (10,826) (10,033) (31,364)
Interest expense (582) (927) (687)
Other income, net 12 59 48
Loss before income tax provision (benefit) (11,396) (10,901) (32,003)
Income tax provision (benefit) 13 (233) 45
Net loss (11,409) (10,668) (32,048)
Other comprehensive income, net of tax:      
Net unrealized gains on available-for-sale securities     16
Comprehensive loss $ (11,409) $ (10,668) $ (32,032)
Net loss per share      
Basic and diluted $ (0.74) $ (1.45) $ (4.86)
Shares used in computing net loss per share      
Basic and diluted 15,393 7,338 6,601
Product [Member]      
Net revenue      
Total net revenue $ 15,053 $ 7,833 $ 4,604
Royalty and Other [Member]      
Net revenue      
Total net revenue $ 1,547 $ 1,009 $ 1,420