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Income Taxes - Additional Information (Details) - USD ($)
$ in Millions
12 Months Ended
Dec. 31, 2018
Dec. 31, 2017
Income Taxes [Line Items]    
U.S. federal corporate tax rate 21.00% 35.00%
Federal AMT tax   $ 0.2
Decrease in valuation allowance during the year $ (56.9) $ (20.6)
Percentage of limitation on federal and state net operating loss carryforwards 98.00%  
Percentage of limitation on federal tax credit carryforwards 100.00%  
Federal    
Income Taxes [Line Items]    
Net operating loss carryforwards, amount $ 196.4  
Net operating loss carryforwards available before expiration 2.5  
Federal | Research and development    
Income Taxes [Line Items]    
Tax credit carryforwards with expiration 9.0  
State    
Income Taxes [Line Items]    
Net operating loss carryforwards, amount 119.9  
Net operating loss carryforwards available before expiration 2.2  
State | Research and development    
Income Taxes [Line Items]    
Tax credit carryforwards without expiration $ 8.2  
Earliest Tax Year    
Income Taxes [Line Items]    
Net operating loss carryforwards, expiration year 2025  
Latest Tax Year    
Income Taxes [Line Items]    
Net operating loss carryforwards, expiration year 2037