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Income Taxes - Reconciliation of Income taxes Provided at Federal Statutory Rate to Actual Income Tax Provision (Benefit) (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2018	Dec. 31, 2017	Dec. 31, 2016
Income Tax Disclosure [Abstract]
Income tax benefit computed at U.S. statutory rate	$ (2,393)	$ (3,815)	$ (11,229)
State income tax (net of federal benefit)	2	3	3
Foreign income tax at rate different from U.S. statutory rate	12	3	(7)
Research and development credits	(194)	(480)	(981)
Stock-based compensation		(40)	75
Amortization of intangible assets	(60)	(100)	(100)
Goodwill impairment	1,482		1,856
Federal tax rate reduction		(26,617)
Valuation allowance changes affecting tax provision	1,158	30,811	10,022
Other	6	2	406
Income tax provision	$ 13	$ (233)	$ 45

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