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The Company and Summary of Significant Accounting Policies - Summary of outstanding warrants to purchase common stock (Detail) - $ / shares
Jun. 30, 2019
Dec. 31, 2018
Pre Funded Common Stock Warrants [Member]    
Class of Warrant or Right [Line Items]    
Number of shares 2,310,776 2,310,776
Exercise price $ 0.001 $ 0.001
Common Stock Warrants One [Member]    
Class of Warrant or Right [Line Items]    
Number of shares 662,500 662,500
Exercise price $ 2.35 $ 2.35
Expiration date Jan. 30, 2023 Jan. 30, 2023
Common Stock Warrants Two [Member]    
Class of Warrant or Right [Line Items]    
Number of shares 36,910,809 36,910,809
Exercise price $ 0.30 $ 0.30
Expiration date Oct. 30, 2023 Oct. 30, 2023