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Income Tax Credit - Schedule of Major Components of Income Tax (Details) - GBP (£)
£ in Thousands
 12 Months Ended
Dec. 31, 2017
Dec. 31, 2016
Dec. 31, 2015
Current tax:      
Total current tax £ 2,291 £ 2,116 £ 1,176
Deferred tax:      
In respect of prior years, deferred tax 1,007 333 430
Total deferred tax 110    
Income tax credit 2,401 2,116 1,176
Current income tax receivable 4,225 2,195 1,182
Deferred tax 81    
U.K.      
Current tax:      
In respect of current year 2,298 1,906 1,182
In respect of prior years 3 235  
Deferred tax:      
Current income tax receivable 4,207 2,141 1,182
U.S.      
Current tax:      
In respect of current year (10) (28) (6)
In respect of prior years   3  
Deferred tax:      
In respect of current year, deferred tax 61    
In respect of prior years, deferred tax 49    
Current income tax receivable 18 £ 54  
Deferred tax £ 81    
Current income tax payable     £ 6