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Income Tax Credit - Schedule of Reconciliation of Accounting Loss per Statement of Operations (Details) - GBP (£)
£ in Thousands
 12 Months Ended
Dec. 31, 2017
Dec. 31, 2016
Dec. 31, 2015
Reconciliation Of Accounting Profit Multiplied By Applicable Tax Rates [Abstract]      
Loss before tax £ (25,486) £ (8,165) £ (6,508)
Tax on loss at standard U.K. tax rate (4,906) (1,633) (1,318)
Expenses not deductible 3,899 1,301 888
Deduction for R&D (3,051) (2,629) (1,650)
Losses surrendered for R&D tax credit 3,051 2,629 1,650
Deferred tax - PY adjustment (49) 24 6
Overseas tax payable 10    
R&D tax credit— U.S. (61)    
R&D tax credit—current year (2,298) (1,906) (1,182)
R&D tax credit—prior years (3) (235)  
Deferred tax asset not recognized 1,007 333 430
Income tax credit £ (2,401) £ (2,116) £ (1,176)