    <SEC-DOCUMENT>0001193125-20-158467-index.html : 20200602
    <SEC-HEADER>0001193125-20-158467.hdr.sgml : 20200602
    <ACCEPTANCE-DATETIME>20200602161104
    ACCESSION NUMBER:		0001193125-20-158467
    CONFORMED SUBMISSION TYPE:	6-K
    PUBLIC DOCUMENT COUNT:		12
    CONFORMED PERIOD OF REPORT:	20200602
    FILED AS OF DATE:		20200602
    DATE AS OF CHANGE:		20200602

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			NuCana plc
    		CENTRAL INDEX KEY:			0001709626
    		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
    		IRS NUMBER:				000000000
    		STATE OF INCORPORATION:			X0
    		FISCAL YEAR END:			1231

    	FILING VALUES:
    		FORM TYPE:		6-K
    		SEC ACT:		1934 Act
    		SEC FILE NUMBER:	001-38215
    		FILM NUMBER:		20937064

    	BUSINESS ADDRESS:
    		STREET 1:		3 LOCHSIDE WAY
    		CITY:			EDINBURGH
    		STATE:			X0
    		ZIP:			EH12 9DT
    		BUSINESS PHONE:		44-0-131-357-1111

    	MAIL ADDRESS:
    		STREET 1:		3 LOCHSIDE WAY
    		CITY:			EDINBURGH
    		STATE:			X0
    		ZIP:			EH12 9DT

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	NuCana BioMed Ltd
    		DATE OF NAME CHANGE:	20170619
    </SEC-HEADER>
    <DOCUMENT>
    <TYPE>6-K
    <SEQUENCE>1
    <FILENAME>d904392d6k.htm
    <DESCRIPTION>6-K
    <TEXT>
    Document 1 - file: d904392d6k.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-99.1
    <SEQUENCE>2
    <FILENAME>d904392dex991.htm
    <DESCRIPTION>EX-99.1
    <TEXT>
    Document 2 - file: d904392dex991.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>3
    <FILENAME>g904392page004.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 3 - file: g904392page004.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>4
    <FILENAME>g904392page005.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 4 - file: g904392page005.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>5
    <FILENAME>g904392page006.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 5 - file: g904392page006.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>6
    <FILENAME>g904392page007.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 6 - file: g904392page007.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>7
    <FILENAME>g904392page008.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 7 - file: g904392page008.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>8
    <FILENAME>g904392page009.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 8 - file: g904392page009.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>9
    <FILENAME>g904392page010.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 9 - file: g904392page010.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>10
    <FILENAME>g904392page011.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 10 - file: g904392page011.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>11
    <FILENAME>g904392page012.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 11 - file: g904392page012.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>12
    <FILENAME>g904392page013.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 12 - file: g904392page013.jpg

    </DOCUMENT>
    </SEC-DOCUMENT>