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Capital Commitments and Contingencies - Additional Information (Details) - GBP (£) | 1 Months Ended | 12 Months Ended
--- | --- | ---
Feb. 29, 2020 | Dec. 31, 2021 | Dec. 31, 2020 | Dec. 31, 2019 | Dec. 31, 2018
Capital Commitments [Line Items] |  |  |  |  |
Employer national insurance contingent liability |  |  | £ 800,000 | £ 1,300,000 |
Prevailing rate of employer national insurance |  |  | 13.80% |  |
Cardiff University [member] |  |  |  |  |
Capital Commitments [Line Items] |  |  |  |  |
Research, collaboration and license agreement additional term | 1 year |  | 2 years |  |
Payments for work performed by sub-licensee |  |  | £ 175,052 | £ 292,607 | £ 292,607
Cardiff University [member] | Scenario Forecast [member] |  |  |  |  |
Capital Commitments [Line Items] |  |  |  |  |
Payments for work performed by sub-licensee |  | £ 250,000 |  |  |
Cardiff Consultants [member] |  |  |  |  |
Capital Commitments [Line Items] |  |  |  |  |
Milestone payments for sub-licensee |  |  | 1,875,000 |  |
Cardiff ProTides [member] |  |  |  |  |
Capital Commitments [Line Items] |  |  |  |  |
Milestone payments for sub-licensee |  |  | £ 4,500,000 |  |

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