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Capital Commitments and Contingencies - Additional Information (Details) - GBP (£)
1 Months Ended 12 Months Ended
Feb. 29, 2020
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Dec. 31, 2018
Capital Commitments [Line Items]          
Employer national insurance contingent liability     £ 800,000 £ 1,300,000  
Prevailing rate of employer national insurance     13.80%    
Cardiff University [member]          
Capital Commitments [Line Items]          
Research, collaboration and license agreement additional term 1 year   2 years    
Payments for work performed by sub-licensee     £ 175,052 £ 292,607 £ 292,607
Cardiff University [member] | Scenario Forecast [member]          
Capital Commitments [Line Items]          
Payments for work performed by sub-licensee   £ 250,000      
Cardiff Consultants [member]          
Capital Commitments [Line Items]          
Milestone payments for sub-licensee     1,875,000    
Cardiff ProTides [member]          
Capital Commitments [Line Items]          
Milestone payments for sub-licensee     £ 4,500,000