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Income Tax Credit - Schedule of Major Components of Income Tax (Details) - GBP (£)
£ in Thousands
 12 Months Ended
Dec. 31, 2020
Dec. 31, 2019
Dec. 31, 2018
Current tax:      
Total current tax £ 5,494 £ 4,238 £ 4,261
Deferred tax:      
In respect of prior years, deferred tax (2,901) (1,962) (2,043)
Total deferred tax (1) 1 (38)
Income tax credit 5,493 4,239 4,223
Current income tax receivable 9,822 8,481 4,263
Deferred tax 44 46  
U.K. [member]      
Current tax:      
In respect of current year 5,516 4,325 4,239
In respect of prior years (22) (86) 19
Deferred tax:      
Current income tax receivable 9,818 8,477 4,239
U.S. [member]      
Current tax:      
In respect of current year   (1)  
In respect of prior years     3
Deferred tax:      
In respect of current year, deferred tax   1 11
In respect of prior years, deferred tax (1)   (49)
Current income tax receivable 4 4 24
Deferred tax £ 44 £ 46 £ 47