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Income Tax Credit - Schedule of Reconciliation of Accounting Loss per Statement of Operations (Details) - GBP (£)
£ in Thousands
 12 Months Ended
Dec. 31, 2020
Dec. 31, 2019
Dec. 31, 2018
Reconciliation Of Accounting Profit Multiplied By Applicable Tax Rates [Abstract]      
Loss before tax £ (36,175) £ (25,651) £ (18,063)
Tax on loss at standard U.K. tax rate (6,873) (4,874) (3,432)
Expenses not deductible 3,972 2,912 1,389
Deduction for R&D (7,228) (5,667) (5,554)
Losses surrendered for R&D tax credit 7,228 5,667 5,554
Deferred tax - PY adjustment 1   49
Overseas tax payable - current year   1  
Overseas tax payable - prior years     (3)
R&D tax credit - U.S.   (1) (11)
R&D tax credit - current year (5,516) (4,325) (4,239)
R&D tax credit - prior years 22 86 (19)
Deferred tax asset not recognized 2,901 1,962 2,043
Income tax credit £ (5,493) £ (4,239) £ (4,223)