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Share-based Payments - Summary of Share Options and Weighted Average Exercise Prices (Details)	12 Months Ended
	Dec. 31, 2020 shares £ / shares	Dec. 31, 2019 shares £ / shares	Dec. 31, 2018 shares £ / shares
Disclosure Of Terms And Conditions Of Sharebased Payment Arrangement [Abstract]
Number of shares, Outstanding, Beginning balance | shares	5,298,840	4,406,252	4,711,502
Number of shares, Granted | shares	2,665,639	1,202,150	253,500
Number of shares, Forfeited | shares	(192,750)	(48,625)	(143,438)
Number of shares, Lapsed | shares	(14,438)	(8,750)
Number of shares, Exercised | shares	(32,500)	(252,187)	(415,312)
Number of shares, Outstanding, Ending balance | shares	7,724,791	5,298,840	4,406,252
Number of shares, Vested and exercisable, Ending balance | shares	4,176,281	3,811,736	3,847,305
Weighted average exercise price per share, Outstanding, Beginning balance | £ / shares	£ 3.91	£ 1.90	£ 1.29
Weighted average exercise price per share, Granted | £ / shares	4.03	10.82	17.01
Weighted average exercise price per share, Forfeited | £ / shares	10.89	10.42	12.74
Weighted average exercise price per share, Lapsed | £ / shares	7.42	3.90
Weighted average exercise price per share, Exercised | £ / shares	0.45	0.50	0.50
Weighted average exercise price per share, Outstanding, Ending balance | £ / shares	3.78	3.91	1.90
Weighted average exercise price per share, Vested and exercisable, Ending balance | £ / shares	£ 2.07	£ 1.15	£ 0.68

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