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Note 2 - Summary of Significant Accounting Policies (Details Textual)
 1 Months Ended 3 Months Ended 12 Months Ended
Apr. 03, 2018
$ / shares
shares
Dec. 31, 2013
USD ($)
Mar. 31, 2020
USD ($)
$ / shares
shares
Mar. 31, 2019
USD ($)
Dec. 31, 2019
USD ($)
$ / shares
shares
Dec. 31, 2011
USD ($)
Dec. 31, 2010
USD ($)
Mar. 31, 2018
$ / shares
shares
Stockholders' Equity Note, Stock Split, Conversion Ratio 6.6841954              
Capital Stock, Shares Authorized (in shares) | shares               210,000,000
Common Stock, Shares Authorized (in shares) | shares 200,000,000   200,000,000   200,000,000     200,000,000
Common Stock, Par or Stated Value Per Share (in dollars per share) | $ / shares $ 0.001   $ 0.001   $ 0.001     $ 0.001
Preferred Stock, Shares Authorized (in shares) | shares 10,000,000       10,000,000     10,000,000
Preferred Stock, Par or Stated Value Per Share (in dollars per share) | $ / shares     $ 0.001   $ 0.001     $ 0.001
Cash Equivalents, at Carrying Value, Total     $ 0   $ 0      
Cash, Uninsured Amount     22,829,591   1,761,278      
Research and Development Assets, Current     882,637   801,780      
State of Texas Emerging Technology Fund Award Amount             $ 4,500,000  
Proceeds from State of Texas Emerging Technology Fund Award           $ 2,250,000 2,250,000  
Revenues, Total            
Fair Value Adjustment of Warrants   $ 2,500,000     0      
Impairment of Long-Lived Assets Held-for-use     $ 0   $ 0      
Grant [Member] | U.S. Treasury Department [Member]                
Revenues, Total             $ 244,500  
Minimum [Member]                
Property, Plant and Equipment, Useful Life (Year)     3 years          
Maximum [Member]                
Property, Plant and Equipment, Useful Life (Year)     5 years