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Note 9 - Subsequent Events (Details Textual) |  |  |  |  |  |  |  | 1 Months Ended | 3 Months Ended | 9 Months Ended |  |  |  |  |  |
--- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | ---
Nov. 10, 2025 USD ($) | Oct. 29, 2025 USD ($) $ / shares shares | Oct. 24, 2025 USD ($) $ / shares shares | Oct. 21, 2025 | Oct. 01, 2025 USD ($) shares | Jun. 11, 2025 USD ($) | Feb. 02, 2024 | Nov. 14, 2025 USD ($) shares | Sep. 30, 2025 USD ($) $ / shares shares | Sep. 30, 2024 USD ($) $ / shares shares | Sep. 30, 2025 USD ($) $ / shares shares | Sep. 30, 2024 USD ($) $ / shares shares | Jun. 30, 2025 $ / shares | Mar. 31, 2025 $ / shares | Dec. 31, 2024 $ / shares | Jun. 30, 2024 $ / shares | Mar. 31, 2024 $ / shares | Dec. 31, 2023 $ / shares
Proceeds from Issuance of Common Stock | $ |  |  |  |  |  |  |  |  |  |  | $ 10,714,593 | $ 8,029,143 |  |  |  |  |  |
Class of Warrant or Right, Exercise Price of Warrants or Rights (in dollars per share) | $ / shares |  |  |  |  |  |  |  |  | $ 499.26 | $ 503.74 | $ 499.26 | $ 503.74 | $ 503.75 | $ 503.75 | $ 503.75 | $ 361.6 | $ 297.21 | $ 4,054.81
Placement Agent Warrants [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class of Warrant or Right, Exercise Price of Warrants or Rights (in dollars per share) | $ / shares |  |  |  |  |  |  |  |  |  | $ 260.44 |  | $ 260.44 |  |  |  |  |  |
The 2025 ELOC Facility [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Stock Issued During Period, Shares, Issued for Services (in shares) |  |  |  |  |  |  |  |  | 341,224 |  |  |  |  |  |  |  |  |
Stock Issued During Period, Shares, New Issues (in shares) |  |  |  |  |  |  |  |  | 341,224 |  | 422,380 |  |  |  |  |  |  |
Proceeds from Issuance of Common Stock | $ |  |  |  |  |  |  |  |  | $ 2,943,745 |  | $ 3,818,631 |  |  |  |  |  |  |
Equity Issuance, Maximum Amount, Available for Issuance | $ |  |  |  |  |  | $ 12,500,000 |  |  |  |  |  |  |  |  |  |  |  |
The 2023 ATM Facility [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Stock Issued During Period, Shares, New Issues (in shares) |  |  |  |  |  |  |  |  | 0 | 42,990 | 338,811 | 46,370 |  |  |  |  |  |
Proceeds from Issuance of Common Stock | $ |  |  |  |  |  |  |  |  |  | $ 1,215,105 | $ 6,895,947 | $ 2,117,752 |  |  |  |  |  |
Scientific Advisory Board Chairman [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Stock Issued During Period, Shares, Issued for Services (in shares) |  |  |  |  |  |  |  |  | 100 | 100 | 300 | 203 |  |  |  |  |  |
Reverse Stock Split [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Stockholders' Equity Note, Stock Split, Conversion Ratio |  |  |  |  |  |  | 40 |  |  |  |  |  |  |  |  |  |  |
Subsequent Event [Member] | October 2025 Private Warrants 1 [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class of Warrant or Right, Number of Securities Called by Warrants or Rights (in shares) |  |  | 487,244 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class of Warrant or Right, Exercise Price of Warrants or Rights (in dollars per share) | $ / shares |  |  | $ 11 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Warrants and Rights Outstanding, Term (Year) |  |  | 24 months |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Proceeds from Issuance of Warrants, Gross | $ |  |  | $ 2,500,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Proceeds from Issuance of Warrants | $ |  |  | $ 5,400,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Subsequent Event [Member] | Placement Agent Warrants [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class of Warrant or Right, Number of Securities Called by Warrants or Rights (in shares) |  | 22,667 | 14,617 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class of Warrant or Right, Exercise Price of Warrants or Rights (in dollars per share) | $ / shares |  | $ 11.25 | $ 14.0125 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Warrants and Rights Outstanding, Term (Year) |  | 24 months | 24 months |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Subsequent Event [Member] | October 2025 Private Warrants 2 [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class of Warrant or Right, Number of Securities Called by Warrants or Rights (in shares) |  | 755,560 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class of Warrant or Right, Exercise Price of Warrants or Rights (in dollars per share) | $ / shares |  | $ 8.75 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Warrants and Rights Outstanding, Term (Year) |  | 24 months |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Proceeds from Issuance of Warrants, Gross | $ |  | $ 6,100,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Proceeds from Issuance of Warrants | $ |  | $ 3,100,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Subsequent Event [Member] | The 2025 ELOC Facility [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Stock Issued During Period, Shares, New Issues (in shares) |  |  |  |  | 326,750 |  |  |  |  |  |  |  |  |  |  |  |  |
Proceeds from Issuance of Common Stock | $ |  |  |  |  | $ 1,434,139 |  |  |  |  |  |  |  |  |  |  |  |  |
Subsequent Event [Member] | October 2024 Registered Direct Offering 1 [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Stock Issued During Period, Shares, New Issues (in shares) |  |  | 243,622 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Shares Issued, Price Per Share (in dollars per share) | $ / shares |  |  | $ 11.21 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Subsequent Event [Member] | October 2025 Registered Direct Offering 2 [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Stock Issued During Period, Shares, New Issues (in shares) |  | 377,780 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Shares Issued, Price Per Share (in dollars per share) | $ / shares |  | $ 9 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Sale of Stock, Cash Fee |  | 7.00% |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Sale of Stock, Management Fee |  | 1.00% |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Sale of Stock, Purchasable Warrants |  | 6.00% |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Subsequent Event [Member] | The 2023 ATM Facility [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Stock Issued During Period, Shares, New Issues (in shares) |  |  |  |  |  |  |  | 242,537 |  |  |  |  |  |  |  |  |  |
Proceeds from Issuance of Common Stock | $ |  |  |  |  |  |  |  | $ 1,006,740 |  |  |  |  |  |  |  |  |  |
Equity Issuance, Maximum Amount, Available for Issuance | $ | $ 11,495,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Subsequent Event [Member] | Scientific Advisory Board Chairman [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Stock Issued During Period, Shares, Issued for Services (in shares) |  |  |  |  | 100 |  |  |  |  |  |  |  |  |  |  |  |  |
Subsequent Event [Member] | Reverse Stock Split [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Stockholders' Equity Note, Stock Split, Conversion Ratio |  |  |  | 50 |  |  |  |  |  |  |  |  |  |  |  |  |  |

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