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v3.25.3

Note 8 - Segment Reporting - Reconciliation of Segment Operations (Details) - USD ($) | 3 Months Ended | 9 Months Ended
--- | --- | ---
Sep. 30, 2025 | Jun. 30, 2025 | Mar. 31, 2025 | Sep. 30, 2024 | Jun. 30, 2024 | Mar. 31, 2024 | Sep. 30, 2025 | Sep. 30, 2024
General and administrative |  | $ 1,153,032 |  |  | $ 1,566,085 |  |  | $ 4,764,617 | $ 9,135,225
Other income |  | 2,405 |  |  | 8,080 |  |  | 14,056 | 58,851
Realized and unrealized loss |  | (183) |  |  | (629) |  |  | (262) | (1,115)
Net loss |  | (3,799,240) | $ (4,674,901) | $ (3,964,601) | (4,315,987) | $ (6,495,846) | $ (5,968,869) | (12,438,742) | (16,780,702)
Operating Segments [Member] |  |  |  |  |  |  |  |  |
Revenues |  | 0 |  |  | 0 |  |  | 0 | 0
Clinical and regulatory |  | 1,680,061 |  |  | 1,740,207 |  |  | 5,046,279 | 5,845,783
Manufacturing |  | 188,532 |  |  | 589,548 |  |  | 1,144,195 | 1,109,388
Research |  | 313,323 |  |  | 240,701 |  |  | 950,640 | 236,855
General and administrative |  | 1,144,444 |  |  | 1,331,484 |  |  | 4,192,630 | 6,605,217
Non-cash expenses(1) | [1],[2] | 19,553 |  |  | 421,498 |  |  | 663,243 | 3,041,195
Other income |  | 2,405 |  |  | 8,080 |  |  | 14,056 | 58,851
Other financing costs |  | (455,549) |  |  | 0 |  |  | (455,549) | 0
Realized and unrealized loss |  | (183) |  |  | (629) |  |  | (262) | (1,115)
Net loss |  | $ 3,799,240 |  |  | $ 4,315,987 |  |  | $ 12,438,742 | $ 16,780,702
[1] | Includes $19,553 and $420,226 of stock-based compensation expense for the three months ended September 30, 2025 and 2024, respectively, and $0 and $1,272 of depreciation and amortization expense for the three months ended September 30, 2025 and 2024, respectively. Includes $663,243 and $3,034,966 of stock-based compensation expense for the nine months ended September 30, 2025 and 2024, respectively, and $0 and $6,230 of depreciation and amortization expense for the nine months ended September 30, 2025 and 2024, respectively, inclusive of the amount stated in the preceding sentence
[2] | Includes $19,553 and $420,226 of stock-based compensation expense for the three months ended September 30, 2025 and 2024, respectively, and $0 and $1,272 of depreciation and amortization expense for the three months ended September 30, 2025 and 2024, respectively. Includes $663,243 and $3,034,966 of stock-based compensation expense for the nine months ended September 30, 2025 and 2024, respectively, and $0 and $6,230 of depreciation and amortization expense for the nine months ended September 30, 2025 and 2024, respectively, inclusive of the amount stated in the preceding sentence.

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