    <SEC-DOCUMENT>0001213900-24-069118-index.html : 20240814
    <SEC-HEADER>0001213900-24-069118.hdr.sgml : 20240814
    <ACCEPTANCE-DATETIME>20240814164755
    ACCESSION NUMBER:		0001213900-24-069118
    CONFORMED SUBMISSION TYPE:	F-1/A
    PUBLIC DOCUMENT COUNT:		30
    FILED AS OF DATE:		20240814
    DATE AS OF CHANGE:		20240814

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			Polyrizon Ltd.
    		CENTRAL INDEX KEY:			0001893645
    		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
    		ORGANIZATION NAME:           	03 Life Sciences
    		IRS NUMBER:				000000000
    		STATE OF INCORPORATION:			L3
    		FISCAL YEAR END:			1231

    	FILING VALUES:
    		FORM TYPE:		F-1/A
    		SEC ACT:		1933 Act
    		SEC FILE NUMBER:	333-266745
    		FILM NUMBER:		241209042

    	BUSINESS ADDRESS:
    		STREET 1:		12/6 BOROCHOV ST.
    		CITY:			RAANANA
    		STATE:			IL
    		ZIP:			4343306
    		BUSINESS PHONE:		972-54-7979668

    	MAIL ADDRESS:
    		STREET 1:		12/6 BOROCHOV ST.
    		CITY:			RAANANA
    		STATE:			IL
    		ZIP:			4343306
    </SEC-HEADER>
    <DOCUMENT>
    <TYPE>F-1/A
    <SEQUENCE>1
    <FILENAME>ea0211091-f1a6_polyrizonltd.htm
    <DESCRIPTION>AMENDMENT NO. 6 TO FORM F-1
    <TEXT>
    Document 1 - file: ea0211091-f1a6_polyrizonltd.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-1.1
    <SEQUENCE>2
    <FILENAME>ea021109101ex1-1_poly.htm
    <DESCRIPTION>FORM OF UNDERWRITING AGREEMENT
    <TEXT>
    Document 2 - file: ea021109101ex1-1_poly.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-4.1
    <SEQUENCE>3
    <FILENAME>ea021109101ex4-1_poly.htm
    <DESCRIPTION>FORM OF WARRANT
    <TEXT>
    Document 3 - file: ea021109101ex4-1_poly.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-4.2
    <SEQUENCE>4
    <FILENAME>ea021109101ex4-2_poly.htm
    <DESCRIPTION>FORM OF WARRANT AGENT AGREEMENT
    <TEXT>
    Document 4 - file: ea021109101ex4-2_poly.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-4.3
    <SEQUENCE>5
    <FILENAME>ea021109101ex4-3_poly.htm
    <DESCRIPTION>FORM OF PRE-FUNDED WARRANT
    <TEXT>
    Document 5 - file: ea021109101ex4-3_poly.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-5.1
    <SEQUENCE>6
    <FILENAME>ea021109101ex5-1_poly.htm
    <DESCRIPTION>OPINION OF KEREN LAW FIRM, ISRAELI COUNSEL TO THE REGISTRANT, AS TO THE VALIDITY OF THE ORDINARY SHARES
    <TEXT>
    Document 6 - file: ea021109101ex5-1_poly.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-5.2
    <SEQUENCE>7
    <FILENAME>ea021109101ex5-2_poly.htm
    <DESCRIPTION>OPINION OF GREENBERG TRAURIG, P.A., US COUNSEL TO THE REGISTRANT
    <TEXT>
    Document 7 - file: ea021109101ex5-2_poly.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.15
    <SEQUENCE>8
    <FILENAME>ea021109101ex10-15_poly.htm
    <DESCRIPTION>LICENSE AGREEMENT WITH SCISPARC LTD
    <TEXT>
    Document 8 - file: ea021109101ex10-15_poly.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.16
    <SEQUENCE>9
    <FILENAME>ea021109101ex10-16_poly.htm
    <DESCRIPTION>CONVERTIBLE LOAN AGREEMENT BETWEEN POLYRIZON LTD. AND CERTAIN SHAREHOLDERS DATED FEBRUARY 4, 2023
    <TEXT>
    Document 9 - file: ea021109101ex10-16_poly.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.17
    <SEQUENCE>10
    <FILENAME>ea021109101ex10-17_poly.htm
    <DESCRIPTION>CONVERTIBLE LOAN AGREEMENT BETWEEN POLYRIZON LTD. AND L.I.A PURE CAPITAL LTD. DATED APRIL 10, 2024
    <TEXT>
    Document 10 - file: ea021109101ex10-17_poly.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.18
    <SEQUENCE>11
    <FILENAME>ea021109101ex10-18_poly.htm
    <DESCRIPTION>CONVERTIBLE LOAN AGREEMENT BETWEEN POLYRIZON LTD. AND L.I.A PURE CAPITAL LTD. AND REUVEN SRUGO CONSTRUCTION COMPANY LTD DATED AUGUST 11, 2024
    <TEXT>
    Document 11 - file: ea021109101ex10-18_poly.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-23.1
    <SEQUENCE>12
    <FILENAME>ea021109101ex23-1_poly.htm
    <DESCRIPTION>CONSENT OF BRIGHTMAN ALMAGOR ZOHAR & CO., A FIRM IN THE DELOITTE GLOBAL NETWORK
    <TEXT>
    Document 12 - file: ea021109101ex23-1_poly.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-99.3
    <SEQUENCE>13
    <FILENAME>ea021109101ex99-3_poly.htm
    <DESCRIPTION>CONSENT OF DIRECTOR NOMINEE
    <TEXT>
    Document 13 - file: ea021109101ex99-3_poly.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>14
    <FILENAME>img_013.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 14 - file: img_013.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>15
    <FILENAME>img_001.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 15 - file: img_001.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>16
    <FILENAME>img_002.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 16 - file: img_002.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>17
    <FILENAME>img_003.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 17 - file: img_003.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>18
    <FILENAME>img_004.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 18 - file: img_004.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>19
    <FILENAME>img_005.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 19 - file: img_005.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>20
    <FILENAME>img_006.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 20 - file: img_006.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>21
    <FILENAME>img_007.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 21 - file: img_007.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>22
    <FILENAME>img_008.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 22 - file: img_008.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>23
    <FILENAME>img_009.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 23 - file: img_009.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>24
    <FILENAME>img_010.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 24 - file: img_010.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>25
    <FILENAME>img_011.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 25 - file: img_011.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>26
    <FILENAME>img_012.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 26 - file: img_012.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>27
    <FILENAME>img_014.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 27 - file: img_014.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>28
    <FILENAME>ex5-1_001.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 28 - file: ex5-1_001.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>29
    <FILENAME>ex5-1_002.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 29 - file: ex5-1_002.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>30
    <FILENAME>ex5-2_001.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 30 - file: ex5-2_001.jpg

    </DOCUMENT>
    </SEC-DOCUMENT>