<DOCUMENT>
<TYPE>EX-99.1
<SEQUENCE>6
<FILENAME>e65715_ex99-1.txt
<DESCRIPTION>PRESS RELEASE
<TEXT>
                                                                    EXHIBIT 99.1

              Applied DNA Sciences Launches SigNature(TM) Botanical DNA
                              Authentication Program


      STONY BROOK, N.Y., May 1 /PRNewswire First Call / -- Applied DNA Sciences,
Inc. (OTC BB:  APDN),  a DNA security  solutions  company,  today  announced the
launch of its SigNature(TM) Botanical DNA Authentication Program ("SigNature(TM)
Program").   APDN  created  the  SigNature(TM)  Program  to  provide  a  secure,
cost-effective  and forensic  method  intended to help preserve and add value to
its customers' brand and product lines.

      The SigNature(TM)  Program is the first initiative by APDN to introduce to
the market a range of ready-to-use  security solutions aimed at brand protection
and authentication and also to address the global need to combat  counterfeiting
and piracy. Counterfeit items continue to pose a significant and growing problem
with consumer  packaged goods,  especially for prestige and  established  brands
worldwide.  In the 2005 DOPIP Global Counterfeit and Piracy Report,  brands were
tracked to counterfeit and piracy seizures and accounted for losses of more than
$1.54 billion dollars (USD).

      Dr. James A.  Hayward,  Chief  Executive  Officer of Applied DNA Sciences,
stated,  "We believe that there are many consumer  packaged goods  especially in
the luxury, retail, and apparel industries that could benefit from the overt and
covert  technologies  that the SigNature(TM)  Program offers.  Our ready-to-use,
proprietary  forensic  methodologies  are designed to protect and complement the
branding and packaging needs of our clients."

      Sectors of commerce  that could  benefit  from the  SigNature(TM)  Program
include:  pharmaceutical,  healthcare,  cosmetic, fragrance, luxury apparel, and
other consumer product driven industries.

      The  SigNature(TM)   Program  is  based  on  APDN's  proprietary  platform
technology  which  uses  plant-derived  DNA  sequences.  Botanical  DNA  can  be
encrypted into inks, paper, thread, holograms and many other mediums. As part of
the  SigNature(TM)  Program  offering,  APDN has created a unique  botanical DNA
SigNature  logo  which   highlights  the  word  "Nature"  and  incorporates  the
scientific  element  including  DNA and its natural  derivation  from  botanical
sources. The logo has been designed to contain embedded botanical DNA, for overt
detection  and forensic  authentication  purposes.  For real-time  detection,  a
proprietary  SigNature  DNA  detection  pen is  applied  over  the  DNA-embedded
SigNature  logo,  prompting a reversible  color  change.  If a reversible  color
change does not occur,  counterfeiting  is  suspected,  triggering  the need for
forensic  authentication  which  is  obtainable  by  sequencing  the  encrypted,
underlying botanical DNA.

      About Applied DNA Sciences, Inc.

      Applied  DNA  Sciences,  Inc.  (APDN)  develops  proprietary  DNA-embedded
security  solutions  that use  plant  DNA to  verify  authenticity  and  protect
corporate and government agencies from counterfeiting,  fraud,  piracy,  product
diversion,  identity  theft and  unauthorized  intrusion into physical plant and
databases.  Our common stock is listed on The  Over-The-Counter  Bulletin  Board
under the symbol "APDN".  Contact:  MeiLin Wan,  Applied DNA Sciences,  Inc., 25
Health Sciences Drive,  Stony Brook,  New York 11790;  Tel:  631-444-6861;  Fax:
631-444.8848; E-mail: info@adnas.com www.ADNAS.com.


                                      -1-
<PAGE>


      The  statements  made by Applied DNA Sciences,  Inc. in this press release
may be  forward-looking  in  nature  and are made  pursuant  to the safe  harbor
provisions  of the  Private  Securities  Litigation  Reform  Act of  1995.  Such
forward-looking  statements  describe the Company's  future plans,  projections,
strategies and  expectations,  and may be identified by words such as "expects",
"anticipates",  "intends", "plans", "believes", "seeks", "estimates" or words of
similar meaning.  These forward-looking  statements are based on assumptions and
involve a number of risks, uncertainties,  situations and other factors that may
cause our or our industry's  actual results,  level of activity,  performance or
achievements  to be  materially  different  from any  future  results,  level of
activity,  performance or achievements expressed or implied by these statements.
These factors include changes in interest rates, market competition,  changes in
the local and national  economies,  and various other factors detailed from time
to time in Applied DNA Sciences'  SEC reports and filings,  including our Annual
Report on Form  10-KSB,  filed on January 12,  2006,  and  subsequent  Quarterly
Reports on Form 10-QSB and Current  Reports on Form 8-K. The Company  undertakes
no obligation to update publicly any  forward-looking  statements to reflect new
information,  events or  circumstances  after the date  hereof  to  reflect  the
occurrence of unanticipated events.


                                      -2-
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