<SEC-DOCUMENT>0001144204-19-043036.txt : 20190830
<SEC-HEADER>0001144204-19-043036.hdr.sgml : 20190830
<ACCEPTANCE-DATETIME>20190830164715
ACCESSION NUMBER:		0001144204-19-043036
CONFORMED SUBMISSION TYPE:	SC 13D
PUBLIC DOCUMENT COUNT:		1
FILED AS OF DATE:		20190830
DATE AS OF CHANGE:		20190830

SUBJECT COMPANY:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			APPLIED DNA SCIENCES INC
		CENTRAL INDEX KEY:			0000744452
		STANDARD INDUSTRIAL CLASSIFICATION:	SERVICES-MISCELLANEOUS BUSINESS SERVICES [7380]
		IRS NUMBER:				592262718
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			0930

	FILING VALUES:
		FORM TYPE:		SC 13D
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	005-78682
		FILM NUMBER:		191070047

	BUSINESS ADDRESS:	
		STREET 1:		50 HEALTH SCIENCES DRIVE
		CITY:			STONY BROOK
		STATE:			NY
		ZIP:			11790
		BUSINESS PHONE:		631-240-8800

	MAIL ADDRESS:	
		STREET 1:		50 HEALTH SCIENCES DRIVE
		CITY:			STONY BROOK
		STATE:			NY
		ZIP:			11790

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	PROHEALTH MEDICAL TECHNOLOGIES INC
		DATE OF NAME CHANGE:	20010504

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	DCC ACQUISITION CORP
		DATE OF NAME CHANGE:	19990211

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	DATALINK CAPITAL CORP/TX/
		DATE OF NAME CHANGE:	19980306

FILED BY:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Hayward James A
		CENTRAL INDEX KEY:			0001357784

	FILING VALUES:
		FORM TYPE:		SC 13D

	MAIL ADDRESS:	
		STREET 1:		C/O 25 HEALTH SCIENCES DRIVE
		STREET 2:		SUITE 113
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			11790
</SEC-HEADER>
<DOCUMENT>
<TYPE>SC 13D
<SEQUENCE>1
<FILENAME>tv528711_sc13d.htm
<DESCRIPTION>SCHEDULE 13D
<TEXT>
<HTML>
<HEAD>
     <TITLE></TITLE>
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<BODY STYLE="font: 10pt Times New Roman, Times, Serif">

<P STYLE="margin: 0"></P>

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<P STYLE="margin: 0"><B>&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt; text-align: center"><B>SECURITIES AND EXCHANGE COMMISSION</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt; text-align: center"><B>Washington, D.C. 20549</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt; text-align: center"><B>&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt; text-align: center"><B>SCHEDULE 13D</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt; text-align: center">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt; text-align: center"><B>Under the Securities Exchange Act of
1934</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt; text-align: center">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt; text-align: center"><FONT STYLE="font-size: 14pt"><B>Applied
DNA Sciences, Inc.</B></FONT></P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt; text-align: center"></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt; text-align: center">(Name of Issuer)</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt; text-align: center"><B>&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt; text-align: center"><B>Common Stock</B></P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt; text-align: center"></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt; text-align: center">(Title of Class of Securities)</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt; text-align: center"><B>&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt; text-align: center"><B>03815U 201</B></P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt; text-align: center"></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt; text-align: center">(CUSIP Number)</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt; text-align: center"><B>&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt; text-align: center"><B>James A. Hayward</B><BR>
<B>50 Health Sciences Drive</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt; text-align: center"><B>Stony Brook, New York 11790</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt; text-align: center"><B>631-240-8800</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt; text-align: center"><B>&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt; text-align: center"></P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt; text-align: center">(Name, Address and Telephone Number of Person<BR>
Authorized to Receive Notices and Communications)</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt; text-align: center"><B>&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt; text-align: center"><B>August 22, 2019</B></P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt; text-align: center"></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt; text-align: center">(Date of Event Which Requires Filing of
this Statement)</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 0.25in">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 0.25in">If the filing person has previously filed a statement
on Schedule 13G to report the acquisition that is the subject of this Schedule 13D, and is filing this schedule because of &sect;&sect;240.13d-l(e),
240.13d-l(f) or 240.13d-l(g), check the following box. <FONT STYLE="font-family: Wingdings; font-size: 10pt">&uml;</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 0.25in"><B>&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 0.25in"><B>Note: </B>Schedules filed in paper format shall
include a signed original and five copies of the schedule, including all exhibits. See &sect;240.13d-7 for other parties to whom
copies of this statement are to be sent.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 0.25in">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 0.25in">The information required on the remainder of this
cover page shall not be deemed to be &ldquo;filed&rdquo; for the purpose of Section 18 of the Securities Exchange Act of 1934 (&ldquo;<B>Act</B>&rdquo;)
or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however,
see the Notes).</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 0.25in">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>


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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
<TR STYLE="vertical-align: top">
    <TD STYLE="width: 33%; font-size: 10pt">CUSIP No.&nbsp;&nbsp;<B>03815U 201</B></TD>
    <TD STYLE="width: 34%; font-size: 10pt; text-align: center"><B>13D</B></TD>
    <TD STYLE="width: 33%; font-size: 10pt; text-align: right"><B>Page 1 of 9 Pages</B></TD></TR>
</TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif; border-collapse: collapse">
<TR STYLE="vertical-align: top">
    <TD STYLE="width: 5%; border: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt">1</TD>
    <TD STYLE="width: 95%; border-top: Black 1pt solid; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt">NAME OF REPORTING PERSON<BR>
<B>James A. Hayward</B></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid; border-left: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt">2</TD>
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt">CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (See Instructions)<BR>
(a) <FONT STYLE="font-family: Wingdings; font-size: 10pt">&uml;</FONT>&nbsp;&nbsp;(b) <FONT STYLE="font-family: Wingdings; font-size: 10pt">&uml;</FONT></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid; border-left: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt">3</TD>
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt">SEC USE ONLY</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid; border-left: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt">4</TD>
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt">SOURCE OF FUNDS (See Instructions)<BR>
<B>PF</B></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid; border-left: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt">5</TD>
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt">CHECK IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(d) or 2(e)&nbsp;&nbsp;<FONT STYLE="font-family: Wingdings; font-size: 10pt">&uml;</FONT></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: Black 1pt solid; border-left: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt">6</TD>
    <TD STYLE="border-right: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt">CITIZENSHIP OR PLACE OF ORGANIZATION<BR>
<B>United States of America</B></TD></TR>
</TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif; border-collapse: collapse">
<TR>
    <TD ROWSPAN="4" STYLE="width: 20%; border: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt; text-align: center">NUMBER OF<BR>
 SHARES<BR>
 BENEFICIALLY<BR>
 OWNED BY<BR>
 EACH<BR>
 REPORTING<BR>
 PERSON WITH</TD>
    <TD STYLE="vertical-align: top; width: 5%; border-top: Black 1pt solid; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt">7</TD>
    <TD STYLE="vertical-align: top; width: 75%; border-top: Black 1pt solid; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt">SOLE VOTING POWER<BR>
<B>7,991,870(1)</B></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt">8</TD>
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt">SHARED VOTING POWER<BR>
<B>0</B></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt">9</TD>
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt">SOLE DISPOSITIVE POWER<BR>
<B>7,991,870(1)</B></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt">10</TD>
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt">SHARED DISPOSITIVE POWER<BR>
<B>0</B></TD></TR>
</TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif; border-collapse: collapse">
<TR STYLE="vertical-align: top">
    <TD STYLE="width: 5%; border-right: Black 1pt solid; border-bottom: Black 1pt solid; border-left: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt">11</TD>
    <TD STYLE="width: 95%; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt">AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON<BR>
<B>7,991,870(1)</B></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid; border-left: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt">12</TD>
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt">CHECK IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES<BR>
 (See Instructions)&nbsp;&nbsp;<FONT STYLE="font-family: Wingdings; font-size: 10pt">&uml;</FONT></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid; border-left: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt">13</TD>
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt">PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11) <BR>
<B>16.38(2)</B></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid; border-left: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt">14</TD>
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt">TYPE OF REPORTING PERSON (See Instructions)<BR>
<B>IN</B></TD></TR>
</TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">(1)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Reflects (i) 2,431,671
shares of Common Stock, (ii) 2,671,262 shares of Common Stock underlying exercisable options and warrants that may be exercised
within 60 days from the date hereof and (iii) 2,888,937 shares of Common Stock issuable upon conversion of an aggregate principal
amount of $1.56 million of secured convertible notes that may be converted at a conversion price of $0.54 per share. Does not reflect
the remaining 12,500 unvested shares subject to options granted on December 21, 2015 pursuant to the Issuer&rsquo;s 2005 Incentive
Stock Plan, which will vest on December 21, 2019.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">(2)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;This percentage
calculation is based on 43,221,209 shares of Common Stock outstanding as of August 23, 2019.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>


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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
<TR STYLE="vertical-align: top">
    <TD STYLE="width: 33%">CUSIP No.&nbsp;&nbsp;<B>03815U 201</B></TD>
    <TD STYLE="width: 34%; text-align: center"><B>13D</B></TD>
    <TD STYLE="width: 33%; text-align: right"><B>Page 2 of 9 Pages</B></TD></TR>
</TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">&nbsp;</P>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0pt 0">Item 1. Security and Issuer</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">This statement on Schedule 13D (the &ldquo;<B>Schedule
13D</B>&rdquo;) relates to the shares of common stock, par value $0.001 per share (&ldquo;<B>Common Stock</B>&rdquo;), of Applied
DNA Sciences, Inc., a Delaware corporation (the &ldquo;<B>Issuer</B>&rdquo;). The address of the principal executive offices of
the Issuer is 50 Health Sciences Drive, Stony Brook, New York 11790. The Common Stock is listed on The Nasdaq Capital Market under
the ticker symbol &ldquo;APDN.&rdquo;</P>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0pt 0">Item 2. Identity and Background</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">(a)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;This Schedule 13D
is being filed by James A. Hayward, an individual (the &ldquo;<B>Reporting Person</B>&rdquo;).</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">(b)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;The principal business
address of the Reporting Person is 50 Health Sciences Drive, Stony Brook, New York 11790.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">(c)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;The principal occupation
or employment of the Reporting Person is as the Chief Executive Officer and President of the Issuer. The Reporting Person is also
the Chairman of the Board of Directors of the Issuer. The principal business address of the Issuer is 50 Health Sciences Drive,
Stony Brook, New York 11790.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">(d)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;During the last
five years, the Reporting Person has not been convicted in a criminal proceeding (excluding traffic violations or similar misdemeanors).</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">(e)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;During the last
five years, the Reporting Person has not been a party to a civil proceeding of a judicial or administrative body of competent jurisdiction
and as a result of such proceeding was or is subject to a judgment, decree or final order enjoining future violations of, or prohibiting
or mandating activities subject to, federal or state securities laws or finding any violation with respect to such laws.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">(f)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;The Reporting Person
is a citizen of the United States of America.</P>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0pt 0">Item 3. Source and Amount of Funds or Other Consideration</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><U>Equity Compensation Issuances</U></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">As a result of the Reporting Person being
the Chairman of the Board of Directors, Chief Executive Officer and President of the Issuer, pursuant to the employment agreement
dated July 1, 2017 (the &ldquo;<B>Employment Agreement</B>&rdquo;) and the Issuer&rsquo;s 2005 Incentive Stock Plan (the &ldquo;<B>Incentive
Plan</B>&rdquo;), as part of his equity compensation for his service to the Issuer, the Issuer has issued to the Reporting Person
options to purchase an aggregate of 2,279,168 shares of the Issuer&rsquo;s Common Stock, which may be exercised within 60 days
of the date hereof and which are deemed to be outstanding for the purpose of computing the percentage of shares of Common Stock
owned by the Reporting Person. Specifically, the Issuer has issued to the Reporting Person the following outstanding options to
purchase shares of the Issuer&rsquo;s Common Stock:</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>


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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
<TR STYLE="vertical-align: top">
    <TD STYLE="width: 33%">CUSIP No.&nbsp;&nbsp;<B>03815U 201</B></TD>
    <TD STYLE="width: 34%; text-align: center"><B>13D</B></TD>
    <TD STYLE="width: 33%; text-align: right"><B>Page 3 of 9 Pages</B></TD></TR>
</TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="border-collapse: collapse; width: 100%; font: 10pt Times New Roman, Times, Serif">
<TR STYLE="vertical-align: bottom">
    <TD NOWRAP STYLE="font-weight: bold; text-align: center; border-bottom: Black 1pt solid">Transaction Date</TD><TD STYLE="font-weight: bold; padding-bottom: 1pt">&nbsp;</TD>
    <TD NOWRAP COLSPAN="2" STYLE="font-weight: bold; text-align: center; border-bottom: Black 1pt solid">Number of Securities<BR> Underlying Unexercised<BR> Options<BR> (Exercisable)</TD><TD STYLE="padding-bottom: 1pt; font-weight: bold"><SUP>&nbsp;</SUP></TD><TD STYLE="padding-bottom: 1pt">&nbsp;</TD>
    <TD NOWRAP COLSPAN="2" STYLE="text-align: center; border-bottom: Black 1pt solid"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>Number of Securities<BR> Underlying Unexercised<BR> Options<BR> </B></P> <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>(Unexercisable)</B></P></TD><TD STYLE="padding-bottom: 1pt">&nbsp;</TD><TD STYLE="font-weight: bold; padding-bottom: 1pt">&nbsp;</TD>
    <TD NOWRAP STYLE="font-weight: bold; text-align: center; border-bottom: Black 1pt solid">Option Expiration Date</TD></TR>
<TR STYLE="vertical-align: bottom; background-color: rgb(204,238,255)">
    <TD STYLE="width: 25%; text-align: center">December 22, 2014</TD><TD STYLE="width: 1%">&nbsp;</TD>
    <TD STYLE="width: 1%; text-align: left">&nbsp;</TD><TD STYLE="width: 22%; text-align: right">175,000</TD><TD STYLE="width: 1%; text-align: left"><SUP>&nbsp;</SUP></TD><TD STYLE="width: 1%">&nbsp;</TD>
    <TD STYLE="width: 1%; text-align: left">&nbsp;</TD><TD STYLE="width: 22%; text-align: right">&nbsp;</TD><TD STYLE="width: 1%; text-align: left">&nbsp;</TD><TD STYLE="width: 1%">&nbsp;</TD>
    <TD STYLE="width: 24%; text-align: center">December 21, 2024</TD></TR>
<TR STYLE="vertical-align: bottom; background-color: White">
    <TD STYLE="text-align: center">&nbsp;</TD><TD>&nbsp;</TD>
    <TD STYLE="text-align: left">&nbsp;</TD><TD STYLE="text-align: right">&nbsp;</TD><TD STYLE="text-align: left"><SUP>&nbsp;</SUP></TD><TD>&nbsp;</TD>
    <TD STYLE="text-align: left">&nbsp;</TD><TD STYLE="text-align: right">&nbsp;</TD><TD STYLE="text-align: left">&nbsp;</TD><TD>&nbsp;</TD>
    <TD STYLE="text-align: center">&nbsp;</TD></TR>
<TR STYLE="vertical-align: bottom; background-color: rgb(204,238,255)">
    <TD STYLE="text-align: center">June 20, 2015</TD><TD>&nbsp;</TD>
    <TD STYLE="text-align: left">&nbsp;</TD><TD STYLE="text-align: right">166,667</TD><TD STYLE="text-align: left"><SUP>(1)</SUP></TD><TD>&nbsp;</TD>
    <TD STYLE="text-align: left">&nbsp;</TD><TD STYLE="text-align: right">&nbsp;</TD><TD STYLE="text-align: left">&nbsp;</TD><TD>&nbsp;</TD>
    <TD STYLE="text-align: center">June 30, 2020</TD></TR>
<TR STYLE="vertical-align: bottom; background-color: White">
    <TD STYLE="text-align: center">&nbsp;</TD><TD>&nbsp;</TD>
    <TD STYLE="text-align: left">&nbsp;</TD><TD STYLE="text-align: right">&nbsp;</TD><TD STYLE="text-align: left"><SUP>&nbsp;</SUP></TD><TD>&nbsp;</TD>
    <TD STYLE="text-align: left">&nbsp;</TD><TD STYLE="text-align: right">&nbsp;</TD><TD STYLE="text-align: left">&nbsp;</TD><TD>&nbsp;</TD>
    <TD STYLE="text-align: center">&nbsp;</TD></TR>
<TR STYLE="vertical-align: bottom; background-color: rgb(204,238,255)">
    <TD STYLE="text-align: center">December 21, 2015</TD><TD>&nbsp;</TD>
    <TD STYLE="text-align: left">&nbsp;</TD><TD STYLE="text-align: right">37,500</TD><TD STYLE="text-align: left"><SUP>&nbsp;</SUP></TD><TD>&nbsp;</TD>
    <TD STYLE="text-align: left">&nbsp;</TD><TD STYLE="text-align: right">12,500</TD><TD STYLE="text-align: left">&nbsp;</TD><TD>&nbsp;</TD>
    <TD STYLE="text-align: center">December 21, 2025</TD></TR>
<TR STYLE="vertical-align: bottom; background-color: White">
    <TD STYLE="text-align: center">&nbsp;</TD><TD>&nbsp;</TD>
    <TD STYLE="text-align: left">&nbsp;</TD><TD STYLE="text-align: right">&nbsp;</TD><TD STYLE="text-align: left"><SUP>&nbsp;</SUP></TD><TD>&nbsp;</TD>
    <TD STYLE="text-align: left">&nbsp;</TD><TD STYLE="text-align: right">&nbsp;</TD><TD STYLE="text-align: left">&nbsp;</TD><TD>&nbsp;</TD>
    <TD STYLE="text-align: center">&nbsp;</TD></TR>
<TR STYLE="vertical-align: bottom; background-color: rgb(204,238,255)">
    <TD STYLE="text-align: center">December 20, 2016</TD><TD>&nbsp;</TD>
    <TD STYLE="text-align: left">&nbsp;</TD><TD STYLE="text-align: right">150,000</TD><TD STYLE="text-align: left"><SUP>&nbsp;</SUP></TD><TD>&nbsp;</TD>
    <TD STYLE="text-align: left">&nbsp;</TD><TD STYLE="text-align: right">&nbsp;</TD><TD STYLE="text-align: left">&nbsp;</TD><TD>&nbsp;</TD>
    <TD STYLE="text-align: center">December 20, 2026</TD></TR>
<TR STYLE="vertical-align: bottom; background-color: White">
    <TD STYLE="text-align: center">&nbsp;</TD><TD>&nbsp;</TD>
    <TD STYLE="text-align: left">&nbsp;</TD><TD STYLE="text-align: right">&nbsp;</TD><TD STYLE="text-align: left"><SUP>&nbsp;</SUP></TD><TD>&nbsp;</TD>
    <TD STYLE="text-align: left">&nbsp;</TD><TD STYLE="text-align: right">&nbsp;</TD><TD STYLE="text-align: left">&nbsp;</TD><TD>&nbsp;</TD>
    <TD STYLE="text-align: center">&nbsp;</TD></TR>
<TR STYLE="vertical-align: bottom; background-color: rgb(204,238,255)">
    <TD STYLE="text-align: center">July 10, 2018</TD><TD>&nbsp;</TD>
    <TD STYLE="text-align: left">&nbsp;</TD><TD STYLE="text-align: right">666,667</TD><TD STYLE="text-align: left"><SUP>(2)</SUP></TD><TD>&nbsp;</TD>
    <TD STYLE="text-align: left">&nbsp;</TD><TD STYLE="text-align: right">&nbsp;</TD><TD STYLE="text-align: left">&nbsp;</TD><TD>&nbsp;</TD>
    <TD STYLE="text-align: center">July 10, 2021</TD></TR>
<TR STYLE="vertical-align: bottom; background-color: White">
    <TD STYLE="text-align: center">&nbsp;</TD><TD>&nbsp;</TD>
    <TD STYLE="text-align: left">&nbsp;</TD><TD STYLE="text-align: right">&nbsp;</TD><TD STYLE="text-align: left"><SUP>&nbsp;</SUP></TD><TD>&nbsp;</TD>
    <TD STYLE="text-align: left">&nbsp;</TD><TD STYLE="text-align: right">&nbsp;</TD><TD STYLE="text-align: left">&nbsp;</TD><TD>&nbsp;</TD>
    <TD STYLE="text-align: center">&nbsp;</TD></TR>
<TR STYLE="vertical-align: bottom; background-color: rgb(204,238,255)">
    <TD STYLE="text-align: center">August 29, 2019</TD><TD>&nbsp;</TD>
    <TD STYLE="text-align: left">&nbsp;</TD><TD STYLE="text-align: right">250,000</TD><TD STYLE="text-align: left"><SUP>&nbsp;</SUP></TD><TD>&nbsp;</TD>
    <TD STYLE="text-align: left">&nbsp;</TD><TD STYLE="text-align: right">&nbsp;</TD><TD STYLE="text-align: left">&nbsp;</TD><TD>&nbsp;</TD>
    <TD STYLE="text-align: center">August 29, 2028</TD></TR>
<TR STYLE="vertical-align: bottom; background-color: White">
    <TD STYLE="text-align: center">&nbsp;</TD><TD>&nbsp;</TD>
    <TD STYLE="text-align: left">&nbsp;</TD><TD STYLE="text-align: right">&nbsp;</TD><TD STYLE="text-align: left"><SUP>&nbsp;</SUP></TD><TD>&nbsp;</TD>
    <TD STYLE="text-align: left">&nbsp;</TD><TD STYLE="text-align: right">&nbsp;</TD><TD STYLE="text-align: left">&nbsp;</TD><TD>&nbsp;</TD>
    <TD STYLE="text-align: center">&nbsp;</TD></TR>
<TR STYLE="vertical-align: bottom; background-color: rgb(204,238,255)">
    <TD STYLE="text-align: center">October 17, 2018</TD><TD>&nbsp;</TD>
    <TD STYLE="text-align: left">&nbsp;</TD><TD STYLE="text-align: right">833,334</TD><TD STYLE="text-align: left"><SUP>(3)</SUP></TD><TD>&nbsp;</TD>
    <TD STYLE="text-align: left">&nbsp;</TD><TD STYLE="text-align: right">&nbsp;</TD><TD STYLE="text-align: left">&nbsp;</TD><TD>&nbsp;</TD>
    <TD STYLE="text-align: center">October 17, 2023</TD></TR>
</TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">(1) These options were originally granted on July 1, 2010. On
June&nbsp;30, 2015, the original options were cancelled and replaced with new options with a term of an additional five&nbsp;years.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">(2) These options were originally granted on July 11, 2011.
On July&nbsp;11, 2018, the original options were cancelled and replaced with new options with a term of an additional three&nbsp;years.
The combined term of these options is a total of 10&nbsp;years.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">(3) These options were originally granted on October 13, 2017.
On October&nbsp;17, 2018, the original options were cancelled and replaced with new options with terms of an additional five&nbsp;years.
The combined terms of these options are a total of 10&nbsp;years.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><U>Promissory Note Purchase and Exchange</U></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">On September 11, 2014, the Issuer issued
and sold a promissory note in the aggregate principal amount of $1,000,000 and bearing interest at a rate of 12.5% per annum to
the Reporting Person. On November 11, 2014, the Reporting Person agreed to exchange for cancellation of his promissory note (including
principal and accrued interest thereon) for 315,171 shares of Common Stock at $3.24 per share and 315,171 warrants at $0.01 per
warrant to purchase an additional 315,171 shares of common stock at an exercise price of $3.50 per share. The warrants must be
exercised by November 20, 2019.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><U>Common Stock and Warrant Purchases</U></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">On November 20, 2014, the Reporting Person
purchased from the Issuer 76,923 shares of Common Stock for $250,000, along with other investors in a public offering. In the public
offering, the Reporting Person also acquired 76,923 warrants at the price of $0.01 per warrant to purchase 76,923 additional shares
of Common Stock at an exercise price of $3.50 per share. The warrants must be exercised by November 20, 2019. All purchases by
the Reporting Person were made with personal funds.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><U>Common Stock Purchases</U></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">On June 28, 2017, the Reporting Person purchased
from the Issuer 142,046 shares of Common Stock for $250,000 in a private placement, along with other investors. All purchases by
the Reporting Person were made with personal funds.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">On August 22, 2019, the Reporting Person
purchased from the Issuer 370,371 shares of Common Stock in a private placement for $100,000 in a private placement, along with
other investors. All purchases by the Reporting Person were made with personal funds.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><U>Secured Convertible Note Purchases</U></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">In addition, on August 31, 2018, the Reporting
Person purchased from the Issuer an aggregate principal amount of $1 million of secured convertible notes due August 30, 2021,
(the &ldquo;<B>August Notes</B>&rdquo;) convertible into 400,000 shares of the Issuer&rsquo;s Common Stock at the conversion price
of $2.50 per share, along with other investors and on November 29, 2018, the Reporting Person purchased an additional aggregate
principal amount of $500,000 of the secured convertible notes due November 28, 2021 (the &ldquo;<B>November Notes</B>&rdquo; and
together with the August Notes, the &ldquo;<B>Notes</B>&rdquo;) convertible into 200,000 shares of the Issuer&rsquo;s Common Stock
at the conversion price of $2.50 per share, along with other investors. The Notes were purchased by the Reporting Person in a private
placement with the Issuer using personal funds.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>


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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
<TR STYLE="vertical-align: top">
    <TD STYLE="width: 33%">CUSIP No.&nbsp;&nbsp;<B>03815U 201</B></TD>
    <TD STYLE="width: 34%; text-align: center"><B>13D</B></TD>
    <TD STYLE="width: 33%; text-align: right"><B>Page 4 of 9 Pages</B></TD></TR>
</TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">The Notes bear interest at the rate of 6%
per annum, payable semi-annually in cash or in kind, at the Issuer&rsquo;s option. The Notes are convertible, in whole or in part,
at any time, at the option of the Reporting Person. The Issuer has the right to require the Reporting Person to convert all or
any part of the Notes into shares of Common Stock if the price of the Common Stock remains at a closing price of $3.50 or more
for a period of twenty consecutive trading days. Upon any Change in Control (as defined in the Notes), the holders of the Notes
have the right to require the Issuer to redeem the Notes, in whole or in part, at a redemption price equal to such Notes&rsquo;
outstanding principal balance plus accrued interest. Until the principal and accrued but unpaid interest under the Notes is paid
in full, or converted into shares of Common Stock pursuant to their terms, the Issuer&rsquo;s obligations under the Notes will
be secured by a lien on substantially all assets of the Issuer and the assets of APDN (B.V.I.) Inc., the Issuer&rsquo;s wholly-owned
subsidiary, in favor of Delaware Trust Company, a Delaware corporation, as collateral agent for the purchasers, pursuant to those
certain security agreements dated as of October 19, 2018, as amended on November 26, 2018, February 29, 2019 and July 19, 2019.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">On July 16, 2019, an amendment to the Notes
was entered into, whereby the maturity date of the August Notes was amended to become November 28, 2021 and the conversion price
of the Notes was amended to $0.54, thereby, the Notes are now convertible into 2,888,937 shares of the Issuer&rsquo;s Common Stock.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">In connection with the purchase of the August
Notes and the November Notes, the Reporting Person also entered into registration rights agreements, dated as August 31, 2018 and
November 29, 2018, respectively, and as amended on July 16, 2019 with the Issuer and the other purchasers of the Notes, pursuant
to which the Issuer has agreed to prepare and file a registration statement with the SEC to register under the Securities Act of
1933, as amended, resales from time to time of the Common Stock issued or issuable upon conversion or redemption of the Notes.
The Issuer is required to file a registration statement within 60 days of receiving a demand registration request from holders
of at least 70% of the outstanding principal balance of the Notes, and to cause the registration statement to be declared effective
within 45 days (or 90 days if the registration statement is reviewed by the SEC).</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><U>Other Issuances</U></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">Prior to 2014, the Reporting Person acquired
1,527,160 shares of Common Stock through various transactions, including but not limited to private placements from the Issuer
using personal funds and the conversion of multiple issuances of promissory notes and convertible notes (acquired from the Issuer
in private placements) into shares of Common Stock. Such promissory notes and convertible notes were acquired by the Reporting
Person using personal funds.</P>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0pt 0">Item 4. Purpose of Transaction</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">The Reporting Person acquired the securities
for investment and through his compensatory arrangements with the Issuer.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">The Reporting Person is currently the Chairman
of the Board of Directors, President and Chief Executive Officer of the Issuer. The Reporting Person intends to continue to participate
in the management and operations of the Issuer as a Director, the President and Chief Executive Officer of the Issuer.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>


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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
<TR STYLE="vertical-align: top">
    <TD STYLE="width: 33%">CUSIP No.&nbsp;&nbsp;<B>03815U 201</B></TD>
    <TD STYLE="width: 34%; text-align: center"><B>13D</B></TD>
    <TD STYLE="width: 33%; text-align: right"><B>Page 5 of 9 Pages</B></TD></TR>
</TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">Additionally, in his capacity as a shareholder
of the Issuer, the Reporting Person reviews his investment in the Issuer on a continuous basis. The Reporting Person expects to
continue to evaluate on an ongoing basis his investment in the Issuer, and may from time to time in the future, subject to applicable
legal or other restrictions and constraints, acquire (including through his compensatory arrangements with the Issuer) or dispose
of shares of Common Stock or derivative securities to the extent deemed advisable in light of market conditions and other factors.
The Reporting Person expects to evaluate on an ongoing basis the Issuer&rsquo;s financial condition, operations, business, operations
and prospects, the market price for the shares of Common Stock, conditions in the securities markets generally, general economic
conditions, and other factors. Among other things, the Reporting Person may purchase shares of Common Stock, or may sell or otherwise
dispose of all or a portion of the shares of Common Stock, in public and private transactions and/or may enter into transactions
to hedge the market risk of some or all positions in, or to obtain greater exposure to, the shares of the Common Stock. Alternatively,
the Reporting Person may determine to dispose of some or all of his shares of Common Stock. Any such transactions may be effected
at any time or from time to time, subject to federal and state securities laws. Any such acquisitions or dispositions may be made,
subject to applicable law, in open market or privately negotiated transactions or otherwise. The Reporting Person reserves the
right to change his plans and intentions at any time and from time as he deems appropriate as he has not yet determined which of
the courses of actions specified in this paragraph he may ultimately take.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in"><FONT STYLE="font-weight: normal">&nbsp;</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in"><FONT STYLE="font-weight: normal">Except
as set forth above, the Reporting Person has no present plans or intentions that would result in or relate to any of the transactions
described in subparagraphs (a) through (j) of Item 4 of Schedule 13D, provided that the Reporting Person may, at any time, review
or reconsider his position with respect to the Issuer and reserves the right to develop such plans or proposals.</FONT></P>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0pt 0">Item 5. Interest in Securities of the Issuer</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0in">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0in">The information contained in Item 3 of this
Schedule 13D is incorporated by reference herein.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">(a)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;The responses of
the Reporting Person referenced in Item 2 above with respect to Rows 11, 12 and 13 of the cover pages of this Schedule 13D that
relate to the aggregate number and percentage of shares of Common Stock (including but not limited to footnotes to such information)
are incorporated herein by reference.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">The aggregate percentage of shares of Common
Stock reported as beneficially owned by the Reporting Person was calculated based on 43,221,2019 shares of Common Stock outstanding
as of August 23, 2019.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">(b)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;The responses of
the Reporting Person with respect to Rows 7, 8, 9 and 10 of the cover pages of this Schedule 13D that relate to the number of shares
of Common Stock as to which the Reporting Person referenced in Item 2 above has sole or shared power to vote or to direct the vote
and sole or shared power to dispose or to direct the disposition (including but not limited to footnotes to such information) are
incorporated herein by reference. The Reporting Person has no present plan or arrangement to act in concert with respect to the
acquisition, holding, voting or disposition of shares of Common Stock, or in other matters.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-right: 0; margin-bottom: 0pt; text-align: left">(c)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Other
than as disclosed in Item 3 above, no transactions in the securities of the Issuer were effected by the Reporting Person during
the past sixty days.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">(d)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;As of the date
hereof, to the best knowledge and belief of the undersigned, no person other than the Reporting Person had the right to receive
or the power to direct the receipt of dividends from, or the proceeds from the sale of, the Common Stock beneficially owned by
the Reporting Person.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>


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    <DIV STYLE="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><P STYLE="margin: 0pt">&nbsp;</P></DIV>
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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
<TR STYLE="vertical-align: top">
    <TD STYLE="width: 33%">CUSIP No.&nbsp;&nbsp;<B>03815U 201</B></TD>
    <TD STYLE="width: 34%; text-align: center"><B>13D</B></TD>
    <TD STYLE="width: 33%; text-align: right"><B>Page 6 of 9 Pages</B></TD></TR>
</TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">(e)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Not applicable.</P>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0pt 0">Item 6. Contracts, Arrangements, Understandings or Relationships
with Respect to Securities of the Issuer</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">The information contained in Items 2, 3,
4 and 5 of this Schedule 13D is incorporated by reference herein.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">To the best knowledge of the Reporting Person,
except as set forth herein in this Schedule 13D, there are no other contracts, arrangements, understandings or relationships (legal
or otherwise), including, but not limited to, transfer or voting of any of the securities, finder&rsquo;s fees, joint ventures,
loan or option arrangements, puts or calls, guarantees of profits, division of profits or loss, or the giving or withholding of
proxies, between the Reporting Person, and any other person, with respect to any securities of the Issuer, including any securities
pledged or otherwise subject to a contingency the occurrence of which would give another person voting power or investment power
over such securities other than standard default and similar provisions contained in loan agreements.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 8.75pt; text-indent: 0.5in">&nbsp;</P>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0pt 0">Item 7. Material to be Filed as an Exhibit</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
<TR STYLE="vertical-align: top">
    <TD STYLE="width: 19%"><B>Exhibit</B></TD>
    <TD STYLE="width: 81%; text-align: center"><B>Description and Date of Document</B></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="padding-left: 0.5in; text-indent: -0.25in">&nbsp;</TD>
    <TD>&nbsp;</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="padding-left: 0.5in; text-indent: -0.25in"><A HREF="http://www.sec.gov/Archives/edgar/data/744452/000157104914006173/t1402092_ex10-29.htm" STYLE="-sec-extract: exhibit">1.</A></TD>
    <TD><A HREF="http://www.sec.gov/Archives/edgar/data/744452/000157104914006173/t1402092_ex10-29.htm" STYLE="-sec-extract: exhibit">Letter Agreement dated November 11, 2014 between Applied DNA Sciences, Inc. and James A. Hayward regarding Exchange of 12.5% Promissory Note, incorporated by reference to the designated exhibit of the Issuer&rsquo;s Registration Statement on Form S-1/A filed with the SEC on November 12, 2014</A></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="padding-left: 0.5in; text-indent: -0.25in">&nbsp;</TD>
    <TD>&nbsp;</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="padding-left: 0.5in; text-indent: -0.25in"><A HREF="http://www.sec.gov/Archives/edgar/data/744452/000157104914006173/t1402092_ex10-25.htm" STYLE="-sec-extract: exhibit">2.</A></TD>
    <TD><A HREF="http://www.sec.gov/Archives/edgar/data/744452/000157104914006173/t1402092_ex10-25.htm" STYLE="-sec-extract: exhibit">Form of Warrant Agreement between Applied DNA Sciences, Inc. and American Stock Transfer &amp; Trust Company, LLC, as warrant agent, incorporated by reference to the designated exhibit of the Issuer&rsquo;s Registration Statement on Form S-1/A filed with the SEC on November 12, 2014</A></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="padding-left: 0.5in; text-indent: -0.25in">&nbsp;</TD>
    <TD>&nbsp;</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="padding-left: 0.5in; text-indent: -0.25in"><A HREF="http://www.sec.gov/Archives/edgar/data/744452/000157104915002558/t81941_ex4-1.htm" STYLE="-sec-extract: exhibit">3.</A></TD>
    <TD><A HREF="http://www.sec.gov/Archives/edgar/data/744452/000157104915002558/t81941_ex4-1.htm" STYLE="-sec-extract: exhibit">First Amendment to Warrant Agreement dated April 1, 2015 between Applied DNA Sciences, Inc. and American Stock Transfer &amp; Trust Company, LLC as warrant agent, incorporated by reference to the designated exhibit of the Issuer&rsquo;s Current Report on Form 8-K filed with the SEC on April 1, 2015</A></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="padding-left: 0.5in; text-indent: -0.25in">&nbsp;</TD>
    <TD>&nbsp;</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="padding-left: 0.5in; text-indent: -0.25in"><A HREF="http://www.sec.gov/Archives/edgar/data/744452/000157104915009962/t83787_ex10-1.htm" STYLE="-sec-extract: exhibit">4.</A></TD>
    <TD><A HREF="http://www.sec.gov/Archives/edgar/data/744452/000157104915009962/t83787_ex10-1.htm" STYLE="-sec-extract: exhibit">Applied DNA Sciences, Inc. 2005 Incentive Stock Plan and form of employee stock option agreement thereunder, as amended and restated as of January 21, 2015, incorporated by reference to the designated exhibit of the Issuer&rsquo;s Annual Report on Form 10-K for the fiscal year ended September 30, 2015 filed with the SEC on December 14, 2015</A></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="padding-left: 0.5in; text-indent: -0.25in">&nbsp;</TD>
    <TD>&nbsp;</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="padding-left: 0.5in; text-indent: -0.25in"><A HREF="http://www.sec.gov/Archives/edgar/data/744452/000157104916016981/t1600484_ex10-1.htm" STYLE="-sec-extract: exhibit">5.</A></TD>
    <TD><A HREF="http://www.sec.gov/Archives/edgar/data/744452/000157104916016981/t1600484_ex10-1.htm" STYLE="-sec-extract: exhibit">Employment Agreement, dated July 1, 2017, between James A. Hayward and Applied DNA Sciences, Inc., incorporated by reference to the designated exhibit of the Issuer&rsquo;s Current Report on Form 8-K filed with the SEC on August 2, 2016</A></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="padding-left: 0.5in; text-indent: -0.25in">&nbsp;</TD>
    <TD>&nbsp;</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="padding-left: 0.5in; text-indent: -0.25in"><A HREF="http://www.sec.gov/Archives/edgar/data/744452/000157104917006298/t1700407_ex10-1.htm" STYLE="-sec-extract: exhibit">6.</A></TD>
    <TD><A HREF="http://www.sec.gov/Archives/edgar/data/744452/000157104917006298/t1700407_ex10-1.htm" STYLE="-sec-extract: exhibit">Form of Subscription Agreement, incorporated by reference to the designated exhibit of the Issuer&rsquo;s Current Report on Form 8-K filed with the SEC on June 28, 2017</A></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="padding-left: 0.5in; text-indent: -0.25in">&nbsp;</TD>
    <TD>&nbsp;</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="padding-left: 0.5in; text-indent: -0.25in"><A HREF="http://www.sec.gov/Archives/edgar/data/744452/000114420418063812/tv508735_ex10-1.htm" STYLE="-sec-extract: exhibit">7.</A></TD>
    <TD><A HREF="http://www.sec.gov/Archives/edgar/data/744452/000114420418063812/tv508735_ex10-1.htm" STYLE="-sec-extract: exhibit">Form of Note, incorporated by reference to the designated exhibit of the Issuer&rsquo;s Current Report on Form 8-K originally filed with the SEC on September 4, 2018 and amended on December 10, 2018</A></TD></TR>
</TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>


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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
<TR STYLE="vertical-align: top">
    <TD STYLE="width: 33%">CUSIP No.&nbsp;&nbsp;<B>03815U 201</B></TD>
    <TD STYLE="width: 34%; text-align: center"><B>13D</B></TD>
    <TD STYLE="width: 33%; text-align: right"><B>Page 7 of 9 Pages</B></TD></TR>
</TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
<TR STYLE="vertical-align: top">
    <TD STYLE="width: 19%"><B>Exhibit</B></TD>
    <TD STYLE="width: 81%; text-align: center"><B>Description and Date of Document</B></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="padding-left: 0.5in; text-indent: -0.25in">&nbsp;</TD>
    <TD>&nbsp;</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="padding-left: 0.5in; text-indent: -0.25in"><A HREF="http://www.sec.gov/Archives/edgar/data/744452/000114420418063812/tv508735_ex10-2.htm" STYLE="-sec-extract: exhibit">8.</A></TD>
    <TD><A HREF="http://www.sec.gov/Archives/edgar/data/744452/000114420418063812/tv508735_ex10-2.htm" STYLE="-sec-extract: exhibit">Registration Rights Agreement, dated August 31, 2018, by and among Applied DNA Sciences, Inc. and the investors named on the signature page thereto, incorporated by reference to the designated exhibit of the Issuer&rsquo;s Current Report on Form 8-K originally filed with the SEC on September 4, 2018 and amended on December 10, 2018</A></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="padding-left: 0.5in; text-indent: -0.25in">&nbsp;</TD>
    <TD>&nbsp;</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="padding-left: 0.5in; text-indent: -0.25in"><A HREF="http://www.sec.gov/Archives/edgar/data/744452/000114420418063812/tv508735_ex10-3.htm" STYLE="-sec-extract: exhibit">9.</A></TD>
    <TD><A HREF="http://www.sec.gov/Archives/edgar/data/744452/000114420418063812/tv508735_ex10-3.htm" STYLE="-sec-extract: exhibit">Securities Purchase Agreement, dated August 31, 2018, by and among Applied DNA Sciences, Inc. and the investors named on the signature page thereto, incorporated by reference to the designated exhibit of the Issuer&rsquo;s Current Report on Form 8-K originally filed with the SEC on September 4, 2018 and amended on December 10, 2018</A></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="padding-left: 0.5in; text-indent: -0.25in">&nbsp;</TD>
    <TD>&nbsp;</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="padding-left: 0.5in; text-indent: -0.25in"><A HREF="http://www.sec.gov/Archives/edgar/data/744452/000114420418063250/tv508537_ex10-1.htm" STYLE="-sec-extract: exhibit">10.</A></TD>
    <TD><A HREF="http://www.sec.gov/Archives/edgar/data/744452/000114420418063250/tv508537_ex10-1.htm" STYLE="-sec-extract: exhibit">Form of Convertible Note incorporated by reference to the designated exhibit of the Issuer&rsquo;s Current Report on Form 8-K filed with the SEC on December 6, 2018</A></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="padding-left: 0.5in; text-indent: -0.25in">&nbsp;</TD>
    <TD>&nbsp;</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="padding-left: 0.5in; text-indent: -0.25in"><A HREF="http://www.sec.gov/Archives/edgar/data/744452/000114420418063250/tv508537_ex10-2.htm" STYLE="-sec-extract: exhibit">11.</A></TD>
    <TD><A HREF="http://www.sec.gov/Archives/edgar/data/744452/000114420418063250/tv508537_ex10-2.htm" STYLE="-sec-extract: exhibit">Registration Rights Agreement, dated November 29, 2018 by and among Applied DNA Sciences, Inc. and the investors named on the signature page thereto, incorporated by reference to the designated exhibit of the Issuer&rsquo;s Current Report on Form 8-K filed with the SEC on December 6, 2018</A></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="padding-left: 0.5in; text-indent: -0.25in">&nbsp;</TD>
    <TD>&nbsp;</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="padding-left: 0.5in; text-indent: -0.25in"><A HREF="http://www.sec.gov/Archives/edgar/data/744452/000114420418063250/tv508537_ex10-3.htm" STYLE="-sec-extract: exhibit">12.</A></TD>
    <TD><A HREF="http://www.sec.gov/Archives/edgar/data/744452/000114420418063250/tv508537_ex10-3.htm" STYLE="-sec-extract: exhibit">Securities Purchase Agreement dated November 29, 2018 by and among Applied DNA Sciences, Inc. and the investors named on the signature page thereto, incorporated by reference to the designated exhibit of the Issuer&rsquo;s Current Report on Form 8-K filed with the SEC on December 6, 2018</A></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="padding-left: 0.5in; text-indent: -0.25in">&nbsp;</TD>
    <TD>&nbsp;</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="padding-left: 0.5in; text-indent: -0.25in"><A HREF="http://www.sec.gov/Archives/edgar/data/744452/000114420418065023/tv507795_ex10-39.htm" STYLE="-sec-extract: exhibit">13.</A></TD>
    <TD><A HREF="http://www.sec.gov/Archives/edgar/data/744452/000114420418065023/tv507795_ex10-39.htm" STYLE="-sec-extract: exhibit">Collateral Agency Agreement dated October 19, 2018, incorporated by reference to the designated exhibit of the Issuer&rsquo;s Form 10-K for the fiscal year ended September 30, 2018, originally filed with the SEC on December 18, 2018 and amended by Amendment No. 1 to Form 10-K filed with the SEC on January 28, 2019 and by Amendment No. 2 to Form 10-K filed with the SEC on April 4, 2019 <FONT STYLE="font-size: 10pt">&nbsp;</FONT></A></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="padding-left: 0.5in; text-indent: -0.25in">&nbsp;</TD>
    <TD>&nbsp;</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="padding-left: 0.5in; text-indent: -0.25in"><A HREF="http://www.sec.gov/Archives/edgar/data/744452/000114420418065023/tv507795_ex10-40.htm" STYLE="-sec-extract: exhibit">14.</A></TD>
    <TD><A HREF="http://www.sec.gov/Archives/edgar/data/744452/000114420418065023/tv507795_ex10-40.htm" STYLE="-sec-extract: exhibit">Security Agreement dated October 19, 2018, incorporated by reference to the designated exhibit of the Issuer&rsquo;s Form 10-K for the fiscal year ended September 30, 2018, originally filed with the SEC on December 18, 2018 and amended by Amendment No. 1 to Form 10-K filed with the SEC on January 28, 2019 and by Amendment No. 2 to Form 10-K filed with the SEC on April 4, 2019</A></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="padding-left: 0.5in; text-indent: -0.25in">&nbsp;</TD>
    <TD>&nbsp;</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="padding-left: 0.5in; text-indent: -0.25in"><A HREF="http://www.sec.gov/Archives/edgar/data/744452/000114420418065023/tv507795_ex10-41.htm" STYLE="-sec-extract: exhibit">15.</A></TD>
    <TD><A HREF="http://www.sec.gov/Archives/edgar/data/744452/000114420418065023/tv507795_ex10-41.htm" STYLE="-sec-extract: exhibit">First Amendment to Security Agreement dated November 26, 2018, incorporated by reference to the designated exhibit of the Issuer&rsquo;s Form 10-K for the fiscal year ended September 30, 2018, originally filed with the SEC on December 18, 2018 and amended by Amendment No. 1 to Form 10-K filed with the SEC on January 28, 2019 and by Amendment No. 2 to Form 10-K filed with the SEC on April 4, 2019</A></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="padding-left: 0.5in; text-indent: -0.25in">&nbsp;</TD>
    <TD>&nbsp;</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="padding-left: 0.5in; text-indent: -0.25in"><A HREF="http://www.sec.gov/Archives/edgar/data/744452/000114420418065023/tv507795_ex10-42.htm" STYLE="-sec-extract: exhibit">16.</A></TD>
    <TD><A HREF="http://www.sec.gov/Archives/edgar/data/744452/000114420418065023/tv507795_ex10-42.htm" STYLE="-sec-extract: exhibit">Guaranty and Security Agreement dated October 19, 2018, incorporated by reference to the designated exhibit of the Issuer&rsquo;s Form 10-K for the fiscal year ended September 30, 2018, originally filed with the SEC on December 18, 2018 and amended by Amendment No. 1 to Form 10-K filed with the SEC on January 28, 2019 and by Amendment No. 2 to Form 10-K filed with the SEC on April 4, 2019&nbsp;&nbsp;<FONT STYLE="font-size: 10pt">&nbsp;&nbsp;</FONT></A></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="padding-left: 0.5in; text-indent: -0.25in">&nbsp;</TD>
    <TD>&nbsp;</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="padding-left: 0.5in; text-indent: -0.25in"><A HREF="http://www.sec.gov/Archives/edgar/data/744452/000114420418065023/tv507795_ex10-43.htm" STYLE="-sec-extract: exhibit">17.</A></TD>
    <TD><A HREF="http://www.sec.gov/Archives/edgar/data/744452/000114420418065023/tv507795_ex10-43.htm" STYLE="-sec-extract: exhibit">Intellectual Property Security Agreement dated October 19, 2018, incorporated by reference to the designated exhibit of the Issuer&rsquo;s Form 10-K for the fiscal year ended September 30, 2018, originally filed with the SEC on December 18, 2018 and amended by Amendment No. 1 to Form 10-K filed with the SEC on January 28, 2019 and by Amendment No. 2 to Form 10-K filed with the SEC on April 4, 2019</A></TD></TR>
</TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>


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    <DIV STYLE="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt"><P STYLE="margin: 0pt">&nbsp;</P></DIV>
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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
<TR STYLE="vertical-align: top">
    <TD STYLE="width: 33%">CUSIP No.&nbsp;&nbsp;<B>03815U 201</B></TD>
    <TD STYLE="width: 34%; text-align: center"><B>13D</B></TD>
    <TD STYLE="width: 33%; text-align: right"><B>Page 8 of 9 Pages</B></TD></TR>
</TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
<TR STYLE="vertical-align: top">
    <TD STYLE="width: 19%"><B>Exhibit</B></TD>
    <TD STYLE="width: 81%; text-align: center"><B>Description and Date of Document</B></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="padding-left: 0.5in; text-indent: -0.25in">&nbsp;</TD>
    <TD>&nbsp;</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="padding-left: 0.5in; text-indent: -0.25in"><A HREF="http://www.sec.gov/Archives/edgar/data/744452/000114420418065023/tv507795_ex10-44.htm" STYLE="-sec-extract: exhibit">18.</A></TD>
    <TD><A HREF="http://www.sec.gov/Archives/edgar/data/744452/000114420418065023/tv507795_ex10-44.htm" STYLE="-sec-extract: exhibit">Intellectual Property Security Agreement dated October 19, 2018, incorporated by reference to the designated exhibit of the Issuer&rsquo;s Form 10-K for the fiscal year ended September 30, 2018, originally filed with the SEC on December 18, 2018 and amended by Amendment No. 1 to Form 10-K filed with the SEC on January 28, 2019 and by Amendment No. 2 to Form 10-K filed with the SEC on April 4, 2019 <FONT STYLE="font-size: 10pt">&nbsp;</FONT></A></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="padding-left: 0.5in; text-indent: -0.25in">&nbsp;</TD>
    <TD>&nbsp;</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="padding-left: 0.5in; text-indent: -0.25in"><A HREF="http://www.sec.gov/Archives/edgar/data/744452/000114420419024873/tv520548_ex10-7.htm" STYLE="-sec-extract: exhibit">19.</A></TD>
    <TD><A HREF="http://www.sec.gov/Archives/edgar/data/744452/000114420419024873/tv520548_ex10-7.htm" STYLE="-sec-extract: exhibit">Omnibus Amendment Agreement, dated February 26, 2019, among the Company, APDN (B.V.I.), Inc., and Delaware Trust Company as collateral agent for the benefit of the buyers listed on Schedule I thereto, incorporated by reference to the designated exhibit of the Issuer&rsquo;s Quarterly Report on Form 10-Q for the quarterly period ended March 31, 2019, filed with the SEC on May 9, 2019</A></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="padding-left: 0.5in; text-indent: -0.25in">&nbsp;</TD>
    <TD>&nbsp;</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="padding-left: 0.5in; text-indent: -0.25in"><A HREF="http://www.sec.gov/Archives/edgar/data/744452/000114420419024873/tv520548_ex10-8.htm" STYLE="-sec-extract: exhibit">20.</A></TD>
    <TD><A HREF="http://www.sec.gov/Archives/edgar/data/744452/000114420419024873/tv520548_ex10-8.htm" STYLE="-sec-extract: exhibit">First Amendment to Intellectual Property Security Agreement, dated February 26, 2019, between the Company and Delaware Trust Company as collateral agent for the benefit of the investors listed thereto, incorporated by reference to the designated exhibit of the Issuer&rsquo;s Quarterly Report on Form 10-Q for the quarterly period ended March 31, 2019, filed with the SEC on May 9, 2019</A></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="padding-left: 0.5in; text-indent: -0.25in">&nbsp;</TD>
    <TD>&nbsp;</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="padding-left: 0.5in; text-indent: -0.25in"><A HREF="http://www.sec.gov/Archives/edgar/data/744452/000114420419024873/tv520548_ex10-9.htm" STYLE="-sec-extract: exhibit">21.</A></TD>
    <TD><A HREF="http://www.sec.gov/Archives/edgar/data/744452/000114420419024873/tv520548_ex10-9.htm" STYLE="-sec-extract: exhibit">First Amendment to Intellectual Property Security Agreement, dated February 26, 2019, between APDN (B.V.I.) Inc. and Delaware Trust Company as collateral agent for the benefit of the investors listed thereto, incorporated by reference to the designated exhibit of the Issuer&rsquo;s Quarterly Report on Form 10-Q for the quarterly period ended March 31, 2019, filed with the SEC on May 9, 2019</A></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="padding-left: 0.5in; text-indent: -0.25in">&nbsp;</TD>
    <TD>&nbsp;</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="padding-left: 0.5in; text-indent: -0.25in"><A HREF="http://www.sec.gov/Archives/edgar/data/744452/000114420419034946/tv525305_ex10-4.htm" STYLE="-sec-extract: exhibit">22.</A></TD>
    <TD><A HREF="http://www.sec.gov/Archives/edgar/data/744452/000114420419034946/tv525305_ex10-4.htm" STYLE="-sec-extract: exhibit">Amendment to Secured Convertible Notes, dated July 16, 2019 by and among the Company and the investors named on the signature page thereof, incorporated by reference to the designated exhibit of the Company&rsquo;s Current Report on Form 8-K, dated July 16, 2019, filed with the SEC on July 17, 2019</A></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="padding-left: 0.5in; text-indent: -0.25in">&nbsp;</TD>
    <TD>&nbsp;</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="padding-left: 0.5in; text-indent: -0.25in"><A HREF="http://www.sec.gov/Archives/edgar/data/744452/000114420419034946/tv525305_ex10-5.htm" STYLE="-sec-extract: exhibit">23.</A></TD>
    <TD><A HREF="http://www.sec.gov/Archives/edgar/data/744452/000114420419034946/tv525305_ex10-5.htm" STYLE="-sec-extract: exhibit">Omnibus Amendment Agreement, dated July 16, 2019 by and among the Company and the parties named on the signature page thereof, incorporated by reference to the designated exhibit of the Company&rsquo;s Current Report on Form 8-K, dated July 16, 2019, filed with the SEC on July 17, 2019</A></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="padding-left: 0.5in; text-indent: -0.25in">&nbsp;</TD>
    <TD>&nbsp;</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="padding-left: 0.5in; text-indent: -0.25in"><A HREF="http://www.sec.gov/Archives/edgar/data/744452/000114420419039521/tv526857_ex10-7.htm" STYLE="-sec-extract: exhibit">24.</A></TD>
    <TD><A HREF="http://www.sec.gov/Archives/edgar/data/744452/000114420419039521/tv526857_ex10-7.htm" STYLE="-sec-extract: exhibit">Second Omnibus Amendment Agreement, dated July 19, 2019 by and among the Company, APDN (B.V.I.) Inc., and Delaware Trust Company, as collateral agent for the benefit of the buyers listed on Schedule I thereto, incorporated by reference to the designated exhibit of the Issuer&rsquo;s Quarterly Report on Form 10-Q for the quarterly period ended June 30, 2019, filed with the SEC on August 13, 2019</A></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="padding-left: 0.5in; text-indent: -0.25in">&nbsp;</TD>
    <TD>&nbsp;</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="padding-left: 0.5in; text-indent: -0.25in"><A HREF="http://www.sec.gov/Archives/edgar/data/744452/000114420419039521/tv526857_ex10-8.htm" STYLE="-sec-extract: exhibit">25.</A></TD>
    <TD><A HREF="http://www.sec.gov/Archives/edgar/data/744452/000114420419039521/tv526857_ex10-8.htm" STYLE="-sec-extract: exhibit">Second Amendment to Intellectual Property Security Agreement, dated July 19, 2019 by the Company in favor of Delaware Trust Company as collateral agent for the secured parties defined therein, incorporated by reference to the designated exhibit of the Issuer&rsquo;s Quarterly Report on Form 10-Q for the quarterly period ended June 30, 2019, filed with the SEC on August 13, 2019</A></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="padding-left: 0.5in; text-indent: -0.25in">&nbsp;</TD>
    <TD>&nbsp;</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="padding-left: 0.5in; text-indent: -0.25in"><A HREF="http://www.sec.gov/Archives/edgar/data/744452/000114420419039521/tv526857_ex10-9.htm" STYLE="-sec-extract: exhibit">26.</A></TD>
    <TD><A HREF="http://www.sec.gov/Archives/edgar/data/744452/000114420419039521/tv526857_ex10-9.htm" STYLE="-sec-extract: exhibit">Second Amendment to Intellectual Property Security Agreement, dated July 19, 2019 by APDN (B.V.I.) Inc. in favor of Delaware Trust Company as collateral agent for the secured parties defined therein, incorporated by reference to the designated exhibit of the Issuer&rsquo;s Quarterly Report on Form 10-Q for the quarterly period ended June 30, 2019, filed with the SEC on August 13, 2019</A></TD></TR>
</TABLE>
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    <TD STYLE="width: 33%">CUSIP No.&nbsp;&nbsp;<B>03815U 201</B></TD>
    <TD STYLE="width: 34%; text-align: center"><B>13D</B></TD>
    <TD STYLE="width: 33%; text-align: right"><B>Page 9 of 9 Pages</B></TD></TR>
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<TR STYLE="vertical-align: top">
    <TD STYLE="width: 19%"><B>Exhibit</B></TD>
    <TD STYLE="width: 81%; text-align: center"><B>Description and Date of Document</B></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="padding-left: 0.5in; text-indent: -0.25in">&nbsp;</TD>
    <TD>&nbsp;</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="padding-left: 0.5in; text-indent: -0.25in"><A HREF="http://www.sec.gov/Archives/edgar/data/744452/000157104917006298/t1700407_ex10-1.htm" STYLE="-sec-extract: exhibit">27.</A></TD>
    <TD><A HREF="http://www.sec.gov/Archives/edgar/data/744452/000157104917006298/t1700407_ex10-1.htm" STYLE="-sec-extract: exhibit">Form of Subscription Agreement, incorporated by reference to the designated exhibit of the Issuer&rsquo;s Current Report on Form 8-K filed with the SEC on August 26, 2019</A></TD></TR>
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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>


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<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-transform: uppercase; text-align: center">&nbsp;</P>

<P STYLE="font: bold 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt; text-transform: uppercase; text-align: center">SIGNATURES</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">After reasonable inquiry and to the best of my knowledge and
belief, I certify that the information set forth in this statement is true, complete and correct.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Date: August 30, 2019</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 3in"><FONT STYLE="text-transform: uppercase">&nbsp;</FONT></P>

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<TR STYLE="vertical-align: top">
    <TD>&nbsp;</TD>
    <TD COLSPAN="2"><FONT STYLE="text-transform: uppercase">James A. Hayward</FONT></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="width: 50%">&nbsp;</TD>
    <TD STYLE="width: 5%">&nbsp;</TD>
    <TD STYLE="width: 45%">&nbsp;</TD></TR>
<TR STYLE="vertical-align: top">
    <TD>&nbsp;</TD>
    <TD>By:</TD>
    <TD STYLE="border-bottom: Black 1pt solid">/s/ James A. Hayward</TD></TR>
<TR STYLE="vertical-align: top">
    <TD>&nbsp;</TD>
    <TD>Name:</TD>
    <TD>James A. Hayward</TD></TR>
</TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>



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