Exhibit 31.3

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CERTIFICATION PURSUANT TO SECTION 302

OF THE SARBANES-OXLEY ACT OF 2002

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I, James A. Hayward, certify that:

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1. I have reviewed this Amendment No. 2 to Annual Report on Form 10-K of Applied DNA Sciences, Inc.; and

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2. Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements made, in light of the circumstances under which such statements were made, not misleading with respect to the period covered by this report.

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Date: January 28, 2022

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/s/ James A. Hayward

James A. Hayward

President, Chief Executive Officer and Chairman

(Principal Executive Officer)

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