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Sunshine Biopharma, Inc.

6500 Trans-Canada Highway

4th Floor

Pointe-Claire, Quebec, Canada H9R 0A5

April 7, 2022

Securities and Exchange Commission

Division of Corporation Finance

100 F Street N.E.

Washington, D.C. 20549

	Re:	Sunshine Biopharma, Inc.
		Registration Statement on Form S-3
		Filed March 30, 2022
		File No. 333- 263998

Ladies and Gentlemen:

Pursuant to Rule 461 promulgated under the Securities Act of 1933, as amended, Sunshine Biopharma, Inc. hereby respectfully requests acceleration of the effectiveness of the above-referenced Registration Statement so that such Registration Statement will become effective as of 9:00 a.m. Eastern Time, April 8, 2022, or as soon as practicable thereafter.

Very truly yours,

Sunshine Biopharma, Inc.

By: /s/ Dr. Steve N. Slilaty                   

Dr, Steve N. Slilaty

Chief Executive Officer