<SEC-DOCUMENT>0001213900-25-014362.txt : 20250214
<SEC-HEADER>0001213900-25-014362.hdr.sgml : 20250214
<ACCEPTANCE-DATETIME>20250214165145
ACCESSION NUMBER:		0001213900-25-014362
CONFORMED SUBMISSION TYPE:	SCHEDULE 13G/A
PUBLIC DOCUMENT COUNT:		1
FILED AS OF DATE:		20250214
DATE AS OF CHANGE:		20250214

SUBJECT COMPANY:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			22nd Century Group, Inc.
		CENTRAL INDEX KEY:			0001347858
		STANDARD INDUSTRIAL CLASSIFICATION:	CIGARETTES [2111]
		ORGANIZATION NAME:           	04 Manufacturing
		IRS NUMBER:				980468420
		STATE OF INCORPORATION:			NV
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SCHEDULE 13G/A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	005-85950
		FILM NUMBER:		25630337

	BUSINESS ADDRESS:	
		STREET 1:		8560 MAIN STREET
		STREET 2:		SUITE 4
		CITY:			WILLIAMSVILLE
		STATE:			NY
		ZIP:			14221
		BUSINESS PHONE:		(716) 270-1523

	MAIL ADDRESS:	
		STREET 1:		8560 MAIN STREET
		STREET 2:		SUITE 4
		CITY:			WILLIAMSVILLE
		STATE:			NY
		ZIP:			14221

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Touchstone Mining LTD
		DATE OF NAME CHANGE:	20051222

FILED BY:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Castaldo Gregory
		CENTRAL INDEX KEY:			0002038245
		ORGANIZATION NAME:           	

	FILING VALUES:
		FORM TYPE:		SCHEDULE 13G/A

	MAIL ADDRESS:	
		STREET 1:		3776 STEVEN JAMES DRIVE
		CITY:			GARNET VALLEY
		STATE:			PA
		ZIP:			19060
</SEC-HEADER>
<DOCUMENT>
<TYPE>SCHEDULE 13G/A
<SEQUENCE>1
<FILENAME>primary_doc.xml
<TEXT>
<XML>
<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/schedule13g" xmlns:com="http://www.sec.gov/edgar/common">
  <headerData>
    <submissionType>SCHEDULE 13G/A</submissionType>
    <filerInfo>
      <filer>
        <filerCredentials>
          <!-- Field: Pseudo-Tag; ID: Name; Data: Castaldo Gregory -->
          <cik>0002038245</cik>
          <ccc>XXXXXXXX</ccc>
        </filerCredentials>
      </filer>
      <liveTestFlag>LIVE</liveTestFlag>


    </filerInfo>
  </headerData>
  <formData>
    <coverPageHeader>
      <amendmentNo>1</amendmentNo>
      <securitiesClassTitle>Common Stock, $0.00001 par value per share</securitiesClassTitle>
      <eventDateRequiresFilingThisStatement>02/14/2025</eventDateRequiresFilingThisStatement>
      <issuerInfo>
        <issuerCik>0001347858</issuerCik>
        <issuerName>22nd Century Group Inc.</issuerName>
        <issuerCusip>90137F400</issuerCusip>
        <issuerPrincipalExecutiveOfficeAddress>
          <com:street1>321 Farmington Road</com:street1>
          <com:city>Mocksville</com:city>
          <com:stateOrCountry>NC</com:stateOrCountry>
          <com:zipCode>27028</com:zipCode>
        </issuerPrincipalExecutiveOfficeAddress>
      </issuerInfo>
      <designateRulesPursuantThisScheduleFiled>
        <designateRulePursuantThisScheduleFiled>Rule 13d-1(c)</designateRulePursuantThisScheduleFiled>
      </designateRulesPursuantThisScheduleFiled>
    </coverPageHeader>
    <coverPageHeaderReportingPersonDetails>


      <reportingPersonName>Gregory Castaldo</reportingPersonName>
      <citizenshipOrOrganization>X1</citizenshipOrOrganization>
      <reportingPersonBeneficiallyOwnedNumberOfShares>
        <soleVotingPower>0.00</soleVotingPower>
        <sharedVotingPower>0.00</sharedVotingPower>
        <soleDispositivePower>0.00</soleDispositivePower>
        <sharedDispositivePower>0.00</sharedDispositivePower>
      </reportingPersonBeneficiallyOwnedNumberOfShares>
      <reportingPersonBeneficiallyOwnedAggregateNumberOfShares>0.00</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>
      <aggregateAmountExcludesCertainSharesFlag>N</aggregateAmountExcludesCertainSharesFlag>
      <classPercent>0</classPercent>
      <typeOfReportingPerson>IN</typeOfReportingPerson>
    </coverPageHeaderReportingPersonDetails>
    <items>
      <item1>
        <issuerName>22nd Century Group Inc.</issuerName>
        <issuerPrincipalExecutiveOfficeAddress>321 Farmington Road Mocksville, North Carolina 27028</issuerPrincipalExecutiveOfficeAddress>
      </item1>
      <item2>
        <filingPersonName>Gregory Castaldo</filingPersonName>
        <principalBusinessOfficeOrResidenceAddress>3776 Steven James Drive Garnet Valley, PA 19060</principalBusinessOfficeOrResidenceAddress>
        <citizenship>Gregory Castaldo is a citizen of the United States</citizenship>
      </item2>
      <item3>
        <notApplicableFlag>Y</notApplicableFlag>
      </item3>
      <item4>
        <amountBeneficiallyOwned>See Item 9 on the cover pages(s) hereto.</amountBeneficiallyOwned>
        <classPercent>See Item 11 on the cover page(s) hereto.</classPercent>
        <numberOfSharesPersonHas>
          <solePowerOrDirectToVote>See Item 5 on the cover pages hereto.</solePowerOrDirectToVote>
          <sharedPowerOrDirectToVote>See Item 6 on the cover pages hereto.</sharedPowerOrDirectToVote>
          <solePowerOrDirectToDispose>See Item 7 on the cover pages hereto.</solePowerOrDirectToDispose>
          <sharedPowerOrDirectToDispose>See Item 8 on the cover pages hereto.</sharedPowerOrDirectToDispose>
        </numberOfSharesPersonHas>
      </item4>
      <item5>
        <notApplicableFlag>N</notApplicableFlag>
        <classOwnership5PercentOrLess>Y</classOwnership5PercentOrLess>
      </item5>
      <item6>
        <notApplicableFlag>Y</notApplicableFlag>
      </item6>
      <item7>
        <notApplicableFlag>Y</notApplicableFlag>
      </item7>
      <item8>
        <notApplicableFlag>Y</notApplicableFlag>
      </item8>
      <item9>
        <notApplicableFlag>Y</notApplicableFlag>
      </item9>
      <item10>
        <notApplicableFlag>N</notApplicableFlag>
        <certifications>By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11.</certifications>
      </item10>
    </items>
    <signatureInformation>
      <reportingPersonName>Gregory Castaldo</reportingPersonName>
      <signatureDetails>
        <signature>/s/ Gregory Castaldo</signature>
        <title>Gregory Castaldo</title>
        <date>02/14/2025</date>
      </signatureDetails>
    </signatureInformation>
  </formData>
</edgarSubmission>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
