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Summary of Significant Accounting Policies - Additional Information (Detail) - USD ($)	1 Months Ended	3 Months Ended		9 Months Ended
	Jul. 31, 2017	Dec. 31, 2018	Dec. 31, 2017	Dec. 31, 2018	Dec. 31, 2017	Mar. 31, 2018	Nov. 01, 2016
Summary Of Significant Accounting Policies [Line Items]
Cash and cash equivalents		$ 35,224,000	$ 47,338,000	$ 35,224,000	$ 47,338,000	$ 43,726,000
Restricted cash		127,000	127,000	127,000	127,000	127,000
Accumulated deficit		$ (253,772,000)		(253,772,000)		$ (234,120,000)
Cash flow from operations				$ 15,298,000	23,246,000
Issuance of common stock		117,769,919		117,769,919		111,032,957
Deferred revenue		$ 580,000		$ 580,000		$ 668,000
Revenue recognized				136,000
Revenue recognized under grants		779,000	1,153,000	2,411,000	3,498,000
Cost of revenues		100,000	200,000	400,000	700,000
Dilutive effect		0	0	$ 0	$ 0
Common stock equivalents excluded from computing diluted net loss per share				15,600,000	14,000,000
Accounting Standards Update 2016-18 [Member]
Summary Of Significant Accounting Policies [Line Items]
Restricted cash							$ 100,000
NIH Research Grants Two [Member]
Summary Of Significant Accounting Policies [Line Items]
Revenue recognized under grants	$ 1,657,000
Grant revenue funding period	3 years
Product [Member]
Summary Of Significant Accounting Policies [Line Items]
Product return revenue				$ 0
Grants [Member]
Summary Of Significant Accounting Policies [Line Items]
Revenue recognized under grants		66,000	260,000	574,000	$ 409,000
Grants [Member] | NIH Research Grants Two [Member]
Summary Of Significant Accounting Policies [Line Items]
Revenue recognized under grants		66,000	$ 260,000	574,000	$ 409,000
Research and Development Services [Member]
Summary Of Significant Accounting Policies [Line Items]
Deferred revenue		$ 580,000		$ 580,000		$ 687,000
At-The-Market Facility [Member]
Summary Of Significant Accounting Policies [Line Items]
Issuance of common stock		5,560,514		5,560,514
Gross proceeds from sale of common stock shares				$ 6,900,000

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