<SEC-DOCUMENT>0001193125-23-301722.txt : 20231222
<SEC-HEADER>0001193125-23-301722.hdr.sgml : 20231222
<ACCEPTANCE-DATETIME>20231222060502
ACCESSION NUMBER:		0001193125-23-301722
CONFORMED SUBMISSION TYPE:	424B5
PUBLIC DOCUMENT COUNT:		2
FILED AS OF DATE:		20231222
DATE AS OF CHANGE:		20231222

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			ORGANOVO HOLDINGS, INC.
		CENTRAL INDEX KEY:			0001497253
		STANDARD INDUSTRIAL CLASSIFICATION:	BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
		ORGANIZATION NAME:           	03 Life Sciences
		IRS NUMBER:				271488943
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			0331

	FILING VALUES:
		FORM TYPE:		424B5
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-252224
		FILM NUMBER:		231507081

	BUSINESS ADDRESS:	
		STREET 1:		11555 SORRENTO VALLEY ROAD
		STREET 2:		SUITE 100
		CITY:			SAN DIEGO
		STATE:			CA
		ZIP:			92121
		BUSINESS PHONE:		858-224-1000

	MAIL ADDRESS:	
		STREET 1:		11555 SORRENTO VALLEY ROAD
		STREET 2:		SUITE 100
		CITY:			SAN DIEGO
		STATE:			CA
		ZIP:			92121

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	REAL ESTATE RESTORATION & RENTAL, INC.
		DATE OF NAME CHANGE:	20100722
</SEC-HEADER>
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<TYPE>424B5
<SEQUENCE>1
<FILENAME>d685260d424b5.htm
<DESCRIPTION>424B5
<TEXT>
<HTML><HEAD>
<TITLE>424B5</TITLE>
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 <BODY BGCOLOR="WHITE">


<Center><DIV STYLE="width:8.5in" align="left">
 <P STYLE="margin-top:0pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman" ALIGN="right"><B>Filed Pursuant to Rule 424(b)(5) </B></P>
<P STYLE="margin-top:0pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman" ALIGN="right"><B>Registration <FONT STYLE="white-space:nowrap">No.&nbsp;333-252224</FONT> </B></P>
<P STYLE="margin-top:12pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman"><B>PROSPECTUS SUPPLEMENT </B></P> <P STYLE="margin-top:0pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman"><B>(To Prospectus dated
January&nbsp;29, 2021) </B></P> <P STYLE="font-size:12pt;margin-top:0pt;margin-bottom:0pt">&nbsp;</P> <P STYLE="margin-top:0pt;margin-bottom:0pt" ALIGN="center">


<IMG SRC="g685260g1221160525646.jpg" ALT="LOGO">
 </P> <P STYLE="margin-top:0pt; margin-bottom:0pt; font-size:24pt; font-family:Times New Roman" ALIGN="center"><B>Organovo Holdings, Inc. </B></P>
<P STYLE="margin-top:12pt; margin-bottom:0pt; font-size:14pt; font-family:Times New Roman" ALIGN="center"><B>Up to $4,442,637 Shares of Common Stock </B></P> <P STYLE="font-size:12pt;margin-top:0pt;margin-bottom:0pt">&nbsp;</P><center>
<P STYLE="line-height:6.0pt;margin-top:0pt;margin-bottom:2pt;border-bottom:1.00pt solid #000000;width:21%">&nbsp;</P></center> <P STYLE="margin-top:12pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman">This prospectus supplement
amends and supplements the information in the prospectus, dated January&nbsp;29, 2021, filed as part of our registration statement on Form <FONT STYLE="white-space:nowrap">S-3</FONT> (File
<FONT STYLE="white-space:nowrap">No.&nbsp;333-252224).</FONT> This prospectus supplement should be read in conjunction with the prospectus and is qualified in its entirety by reference thereto, except to the extent that the information herein amends
or supersedes the information contained in prospectus. This prospectus supplement is not complete without, and may only be delivered or utilized in connection with, the prospectus and any future amendments or supplements thereto. </P>
<P STYLE="margin-top:12pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman">We filed the prospectus to register the offer and sale of shares of our common stock from time to time pursuant to the terms of a sales agreement dated
March&nbsp;16, 2018 (the &#147;Sales Agreement&#148;) that we entered into with H.C. Wainwright&nbsp;&amp; Co., LLC and JonesTrading Institutional Services LLC (each an &#147;Agent&#148; and together, the &#147;Agents&#148;), pursuant to which we
may offer and sell shares of our common stock through the Agents, having an aggregate offering price of up to $50,000,000. As of the date of this prospectus supplement, we have sold $22.8&nbsp;million of shares of our common stock through the Agents
under the Sales Agreement pursuant to the prospectus, which leaves $27.2&nbsp;million of common stock available under the prospectus, without giving effect to any offering limit imposed by General Instruction I.B.6 of Form <FONT
STYLE="white-space:nowrap">S-3.</FONT> </P> <P STYLE="margin-top:12pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman">We are filing this prospectus supplement to amend the prospectus to update the amount of shares of our common
stock we are eligible to sell under General Instruction I.B.6 of Form <FONT STYLE="white-space:nowrap">S-3.</FONT> As of December&nbsp;22, 2023, the aggregate market value of our outstanding common stock held by
<FONT STYLE="white-space:nowrap">non-affiliates</FONT> was approximately $16.8&nbsp;million, based on 9,147,815 shares of our outstanding common stock that were held by <FONT STYLE="white-space:nowrap">non-affiliates</FONT> on such date and a price
of $1.835 per share, which was the price at which our common stock was last sold on the Nasdaq Capital Market on November&nbsp;7, 2023 (a date within 60 days of the date hereof). In the past 12 calendar months, we have offered and sold pursuant to
General Instruction I.B.6 of Form <FONT STYLE="white-space:nowrap">S-3</FONT> an aggregate of 841,600 shares of our common stock for gross proceeds of approximately $1.15&nbsp;million. </P>
<P STYLE="margin-top:12pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman">We are filing this prospectus supplement to amend and supplement the information in the prospectus based on the amount of securities that we are eligible to
sell under General Instruction I.B.6 of Form <FONT STYLE="white-space:nowrap">S-3.</FONT> After giving effect to the $5,595,413 offering limit imposed by General Instruction I.B.6 of Form <FONT STYLE="white-space:nowrap">S-3</FONT> and deducting
amounts offered and sold pursuant to General Instruction I.B.6 of Form <FONT STYLE="white-space:nowrap">S-3</FONT> in the past 12 months, we may offer and sell additional shares of our common stock having an aggregate offering price of up to
$4,442,637 from time to time through the Agents in accordance with the terms of the Sales Agreement. </P> <P STYLE="margin-top:12pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman">Our common stock is listed on the Nasdaq Capital
Market under the symbol &#147;ONVO&#148;. On December&nbsp;21, 2023, the last reported sale price of our common stock on the Nasdaq Capital Market was $1.11 per share. </P>
<P STYLE="font-size:12pt;margin-top:0pt;margin-bottom:0pt">&nbsp;</P><center> <P STYLE="line-height:6.0pt;margin-top:0pt;margin-bottom:2pt;border-bottom:1.00pt solid #000000;width:21%">&nbsp;</P></center>
<P STYLE="margin-top:12pt; margin-bottom:0pt; font-size:12pt; font-family:Times New Roman"><B>Investing in our securities involves risks. You should read this prospectus supplement and the documents we incorporate herein by reference carefully
before you make your investment decision. See &#147;Risk Factors&#148; set forth in the documents we file with the Securities and Exchange Commission that are incorporated by reference herein for more information. </B></P>
<P STYLE="margin-top:12pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman"><B>Neither the Securities and Exchange Commission nor any state securities commission has approved or disapproved of these securities or passed upon the
accuracy or adequacy of this prospectus supplement. Any representation to the contrary is a criminal offense. </B></P> <P STYLE="font-size:12pt;margin-top:0pt;margin-bottom:0pt">&nbsp;</P><center>
<P STYLE="line-height:6.0pt;margin-top:0pt;margin-bottom:2pt;border-bottom:1.00pt solid #000000;width:21%">&nbsp;</P></center> <P STYLE="font-size:12pt;margin-top:0pt;margin-bottom:0pt">&nbsp;</P>
<TABLE CELLSPACING="0" CELLPADDING="0" WIDTH="100%" BORDER="0" STYLE="BORDER-COLLAPSE:COLLAPSE; font-family:Times New Roman; font-size:16pt" ALIGN="center">


<TR>

<TD WIDTH="56%"></TD>

<TD VALIGN="bottom" WIDTH="1%"></TD>
<TD WIDTH="43%"></TD></TR>


<TR STYLE="font-size:1pt">
<TD HEIGHT="8"></TD>
<TD HEIGHT="8" COLSPAN="2"></TD></TR>
<TR STYLE="page-break-inside:avoid ; font-family:Times New Roman; font-size:16pt">
<TD VALIGN="top"><B>H.C.&nbsp;Wainwright&nbsp;&amp;&nbsp;Co.</B></TD>
<TD VALIGN="bottom">&nbsp;</TD>
<TD VALIGN="top" ALIGN="right"><B>JonesTrading</B></TD></TR>
</TABLE> <P STYLE="margin-top:12pt; margin-bottom:0pt; font-size:10pt; font-family:Times New Roman" ALIGN="center"><B>The date of this prospectus supplement is December&nbsp;22, 2023 </B></P>
</DIV></Center>

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end
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
