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CONSOLIDATED STATEMENTS OF CASH FLOWS (Parenthetical) - USD ($)
 12 Months Ended
Dec. 31, 2017
Dec. 31, 2016
Dec. 31, 2015
Conversion of Stock [Line Items]      
Non-cash charge recorded to finance expense as result of warrant exchange     $ 1,284,354
Warrants issued as consideration for placement agent services $ 353,721 $ 308,239  
Amount of direct issuance expense allocated to Series C-1 and Series C-2 Warrants and recorded as a reduction of additional paid in capital 108,197 102,088  
Amount of direct issuance expense allocated to Series C Preferred Stock and recorded as a reduction of temporary equity 218,383 206,151  
Amount classified out of stockholders deficit and presented as Warrants with Down-Round Protection within long-term liabilities   $ 341,662  
Amount of direct issuance expense allocated to Series D-1, D-2 and Series C-3 Warrants and recorded as a reduction of additional paid in capital 12,405    
Amount of direct issuance expense allocated to Series D common stock recorded as a reduction of additional paid in capital 14,736    
Series B-1 Warrant [Member]      
Conversion of Stock [Line Items]      
Number of warrants exchanged     1,200,710
Increase (decrease) in equity due to exchange of warrants     $ 1,833,876
Series B-2 Warrant [Member]      
Conversion of Stock [Line Items]      
Number of warrants exchanged     1,200,710
Increase (decrease) in equity due to exchange of warrants     $ 1,612,186
Warrant [Member]      
Conversion of Stock [Line Items]      
Number of warrants exchanged   1,440,880  
Increase (decrease) in equity due to exchange of warrants   $ (1,587,556)  
Series B Preferred Stock [Member]      
Conversion of Stock [Line Items]      
Number of Series A Preferred Stock shares exchanged for Series B Preferred Stock shares     6,931
Increase (decrease) in equity due to exchange of warrants     $ 3,502,536
Stock dividend 854,647 647,215 $ 390,219
Series B Preferred Stock [Member] | Conversion of Preferred Stock Into Common Stock [Member]      
Conversion of Stock [Line Items]      
Number of preferred shares converted     400
Stock issued upon conversion     68,966
Amount of stock converted     $ 178,720
Series C Preferred Stock [Member]      
Conversion of Stock [Line Items]      
Stock dividend 566,033 152,480  
Series B and C Preferred Stock [Member]      
Conversion of Stock [Line Items]      
Stock dividend $ 1,420,680 $ 799,695  
Interest rate 9.00% 9.00%  
Series A Preferred Stock [Member]      
Conversion of Stock [Line Items]      
Number of Series A Preferred Stock shares exchanged for Series B Preferred Stock shares     6,931
Increase (decrease) in equity due to exchange of warrants     $ (4,076,688)
Cash dividend $ 9,400 $ 4,700 $ 0
Series A Preferred Stock [Member] | Conversion of Preferred Stock Into Common Stock [Member]      
Conversion of Stock [Line Items]      
Number of preferred shares converted     100
Stock issued upon conversion     17,242
Amount of stock converted     $ 58,817