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General (Details Narrative) - USD ($)	3 Months Ended
	Mar. 31, 2018	Mar. 31, 2017	Dec. 31, 2017
Accumulated deficit	$ 49,724,998		$ 47,368,612
Stockholder's deficit	16,286,538		$ 16,574,933
Proceeds from issuance of common stock, net of issuance expenses	$ 773,302
Common stock par value	$ 0.001		$ 0.001
Series D Units [Member]
Proceeds from issuance of common stock, net of issuance expenses	$ 1,697,700
Number of shares issued during period	435,556
Common stock par value	$ 0.001
Series D Units [Member] | Exercise Price One [Member]
Warrant term	5 years
Warrant exercise price	$ 4.50
Series D Units [Member] | Exercise Price Two [Member]
Warrant term	5 years
Warrant exercise price	$ 5.75
Series D Units [Member] | Exercise Price Three [Member]
Warrant term	5 years
Warrant exercise price	$ 7.75

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