<SEC-DOCUMENT>0001178913-25-001128.txt : 20250331
<SEC-HEADER>0001178913-25-001128.hdr.sgml : 20250331
<ACCEPTANCE-DATETIME>20250331083319
ACCESSION NUMBER:		0001178913-25-001128
CONFORMED SUBMISSION TYPE:	424B3
PUBLIC DOCUMENT COUNT:		2
FILED AS OF DATE:		20250331
DATE AS OF CHANGE:		20250331

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			TRINITY BIOTECH PLC
		CENTRAL INDEX KEY:			0000888721
		STANDARD INDUSTRIAL CLASSIFICATION:	IN VITRO & IN VIVO DIAGNOSTIC SUBSTANCES [2835]
		ORGANIZATION NAME:           	03 Life Sciences
		EIN:				000000000
		STATE OF INCORPORATION:			L2
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		424B3
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-286020
		FILM NUMBER:		25789078

	BUSINESS ADDRESS:	
		STREET 1:		IDA BUSINESS PARK, BRAY, CO WICKLOW
		STREET 2:		IRELAND
		CITY:			DUBLIN IRELAND
		STATE:			L2
		ZIP:			18
		BUSINESS PHONE:		01135312955111

	MAIL ADDRESS:	
		STREET 1:		3 ROCK ROAD
		STREET 2:		SANDYFORD INDUSTRIAL ESTATES
		CITY:			DUBLIN IRELAND
		STATE:			L2
		ZIP:			18
</SEC-HEADER>
<DOCUMENT>
<TYPE>424B3
<SEQUENCE>1
<FILENAME>zk2532944.htm
<DESCRIPTION>424B3
<TEXT>
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          <td style="width: 50.00%;"><font style="font-weight: bold;">PROSPECTUS</font></td>
          <td style="width: 50%; text-align: right; vertical-align: bottom;"><font style="font-family: 'Times New Roman',Times,serif; font-weight: bold;">Filed Pursuant to Rule 424(b)(3)</font></td>
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        <tr>
          <td style="width: 50.00%;"><br>
          </td>
          <td style="width: 50%; text-align: right; vertical-align: bottom; font-weight: bold;">Registration No. 333-286020</td>
        </tr>

    </table>
    <br>
    <div style="text-align: center; line-height: 1.25; font-weight: bold;">TRINITY BIOTECH PLC</div>
    <div style="line-height: 1.25;">&#160;</div>
    <div style="text-align: center; line-height: 1.25;"><img src="image00001.jpg"></div>
    <div style="line-height: 1.25;">&#160;</div>
    <div style="text-align: center; line-height: 1.25; font-weight: bold;">4,290,000 American Depositary Shares</div>
    <div style="text-align: center; line-height: 1.25; font-weight: bold;">representing</div>
    <div style="text-align: center; line-height: 1.25; font-weight: bold;">
      <div style="line-height: 1.25; color: #000000; font-family: 'Times New Roman', serif; font-weight: bold;">85,800,000 A Ordinary Shares</div>
    </div>
    <div style="line-height: 1.25;"><br style="line-height: 1.25;">
    </div>
    <div style="text-align: justify; text-indent: 36pt; line-height: 1.25;">
      <div style="text-indent: 36pt; line-height: 1.25; color: #000000; font-family: 'Times New Roman', serif;">
        <div style="text-indent: 36pt; line-height: 1.25; color: #000000;">This prospectus relates to the resale, from time to time, by the selling shareholder named in this prospectus or its permitted assigns, of up to 4,290,000 American Depositary Shares
          (&#8220;ADSs&#8221;) (each ADS represents 20 A Ordinary Shares, par value $0.0109 per share), including up to (i) 1.79 million ADSs that Perceptive Credit Holdings II, LP (&#8220;Perceptive II&#8221;) acquired from us on January 30, 2024 in connection with an
          acquisition (the &#8220;Waveform Acquisition&#8221;) pursuant to an asset and share purchase agreement&#160;among TRIB Biosensors Inc., our wholly-owned subsidiary, as purchaser, and Waveform Technologies, Inc. (&#8220;Waveform&#8221;) and the other seller parties thereto,
          (ii) 0.5 million ADSs that are issuable upon the exercise, from time to time, of an outstanding warrant&#160; (&#8220;Warrant #1&#8221;) of Perceptive Credit Holdings III, LP, an affiliate of Perceptive II (&#8220;Perceptive III&#8221; and, together with Perceptive II,
          &#8220;Perceptive&#8221; or the &#8220;selling shareholder&#8221;) that Perceptive III acquired from us on January&#160; 27, 2022, pursuant to the terms of a credit agreement and guaranty, initially dated December 15, 2021 (the &#8220;Original Credit Agreement&#8221;), among us and the
          other obligors party thereto and Perceptive III, as administrative agent and lender, (iii) 0.5 million ADSs that are issuable upon the exercise, from time to time, of an outstanding warrant ( &#8220;Warrant #2&#8221;) that Perceptive III acquired from us on
          January 30, 2024, in connection with the second amendment and restatement of the Original Credit Agreement, (iv) 1.0 million ADSs that are issuable upon exercise, from time to time, of an outstanding warrant ( &#8220;Warrant #3&#8221;) that Perceptive III
          acquired from us on December 23, 2024, in connection with the third amendment and restatement of the Original Credit Agreement, and (v) 0.5 million ADSs that are issuable upon exercise, from time to time, of an outstanding warrant (&#8220;Warrant #4&#8221;
          and, together with Warrant #1, Warrant #2 and Warrant #3, collectively the &#8220;Warrants&#8221;) that Perceptive II acquired from us on December 23, 2024, in connection with&#160; the extension of a deferred consideration payment related to the Waveform
          Acquisition. Pursuant to amendments to the Warrants in connection with the third amendment and restated of the Original Credit Agreement, the Warrants have an exercise price of $0.8000 per ADS ($0.11 per A Ordinary Share), for an aggregate
          exercise price of up to $2,000,000.&#160; Warrant #1 expires on January 27, 2029, Warrant #2 expires on January 30, 2031, and Warrant #3 and Warrant #4 expire on December 23, 2031. The ADSs are evidenced by American Depositary Receipts, or ADRs.&#160;</div>
      </div>
    </div>
    <div style="line-height: 1.25;">&#160;</div>
    <div style="text-align: justify; text-indent: 36pt; line-height: 1.25;">
      <div style="text-indent: 36pt; line-height: 1.25; font-family: 'Times New Roman',serif;">
        <div style="text-indent: 36pt; line-height: 1.25; color: #000000; font-family: 'Times New Roman', serif;">
          <div style="text-indent: 36pt; line-height: 1.25; font-family: 'Times New Roman', Times, serif;">Our ADSs are listed on The NASDAQ Global Select Market (&#8220;Nasdaq&#8221;) under the symbol &#8220;TRIB.&#8221;&#160; On March 28, 2025,
            the closing price of an ADS on The NASDAQ Global Select Market was $0.641.&#160;&#160; Perceptive may offer and sell any of the ADSs from time to time at fixed prices, at market prices or at negotiated prices, and may engage a broker, dealer
            or&#160;underwriter to sell the ADSs. For additional information on the possible methods of sale that may be used by Perceptive, you should refer to the section entitled &#8220;Plan of Distribution&#8221; elsewhere in this prospectus. We will not receive any
            proceeds from the sale of any ADSs by Perceptive. We do not know when or in what amount Perceptive may offer the ADSs for sale. Perceptive may sell any, all or none of the ADSs offered by this prospectus.</div>
        </div>
      </div>
    </div>
    <div style="line-height: 1.25;">&#160;</div>
    <div style="text-align: justify; text-indent: 36pt; line-height: 1.25;"><font style="font-weight: bold;">INVESTING IN THE ADSs INVOLVES A HIGH DEGREE OF RISK.&#160; BEFORE BUYING ANY SECURITIES, YOU SHOULD CAREFULLY CONSIDER THE RISK FACTORS DESCRIBED IN
        &#8220;RISK FACTORS&#8221; BEGINNING ON PAGE 5 OF THIS PROSPECTUS AND UNDER SIMILAR HEADINGS IN THE OTHER DOCUMENTS THAT ARE INCORPORATED BY REFERENCE INTO THIS PROSPECTUS</font>.</div>
    <div style="margin-right: 0.1pt; margin-left: 0.1pt; line-height: 1.25;">&#160;</div>
    <div style="text-align: justify; text-indent: 36pt; line-height: 1.25; font-weight: bold;">NEITHER THE SECURITIES AND EXCHANGE COMMISSION (THE &#8220;COMMISSION&#8221;) NOR ANY STATE SECURITIES COMMISSION HAS APPROVED OR DISAPPROVED OF THESE SECURITIES OR
      DETERMINED IF THIS PROSPECTUS ARE TRUTHFUL OR COMPLETE. ANY REPRESENTATION TO THE CONTRARY IS A CRIMINAL OFFENSE.</div>
    <div style="line-height: 1.25;">&#160;</div>
    <div style="text-align: center; line-height: 1.25;">
      <div style="line-height: 1.25; color: #000000; font-family: 'Times New Roman', serif;">
        <div style="line-height: 1.25; font-family: 'Times New Roman', Times, serif;">The date of this prospectus is&#160;March 31, 2025.</div>
      </div>
    </div>
    <div style="line-height: 1.25;"><br style="line-height: 1.25;">
    </div>
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    <div style="text-align: center; line-height: 1.25; font-weight: bold;"><u>TABLE OF CONTENTS</u></div>
    <div style="line-height: 1.25;">&#160;</div>
    <table cellspacing="0" cellpadding="0" style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000;" id="z098919f3c49a44eb943b48c5a7eab16d">

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          <td style="width: 92.48%; vertical-align: top;">
            <div style="line-height: 1.25;">&#160;</div>
          </td>
          <td style="width: 7.52%; vertical-align: top; border-bottom: #000000 2px solid;">
            <div style="text-align: center; line-height: 1.25; font-weight: bold;">Page</div>
          </td>
        </tr>
        <tr>
          <td style="width: 92.48%; vertical-align: top;">
            <div style="line-height: 1.25;"><a href="#FORWARD">FORWARD&#8209;LOOKING STATEMENTS</a></div>
          </td>
          <td style="width: 7.52%; vertical-align: bottom;">
            <div style="text-align: center; line-height: 1.25;">1</div>
          </td>
        </tr>
        <tr>
          <td style="width: 92.48%; vertical-align: top;">
            <div style="line-height: 1.25;"><a href="#SUMMARY">PROSPECTUS SUMMARY</a></div>
          </td>
          <td style="width: 7.52%; vertical-align: bottom;">
            <div style="text-align: center; line-height: 1.25;">3</div>
          </td>
        </tr>
        <tr>
          <td style="width: 92.48%; vertical-align: top;">
            <div style="line-height: 1.25;"><a href="#OFFERING">THE OFFERING</a></div>
          </td>
          <td style="width: 7.52%; vertical-align: bottom;">
            <div style="text-align: center; line-height: 1.25;">4</div>
          </td>
        </tr>
        <tr>
          <td style="width: 92.48%; vertical-align: top;">
            <div style="line-height: 1.25;"><a href="#RISK">RISK FACTORS</a></div>
          </td>
          <td style="width: 7.52%; vertical-align: bottom;">
            <div style="text-align: center; line-height: 1.25;">5</div>
          </td>
        </tr>
        <tr>
          <td style="width: 92.48%; vertical-align: top;">
            <div style="line-height: 1.25;"><a href="#PROCEEDS">USE OF PROCEEDS</a></div>
          </td>
          <td style="width: 7.52%; vertical-align: bottom; text-align: center;">10</td>
        </tr>
        <tr>
          <td style="width: 92.48%; vertical-align: top;">
            <div style="line-height: 1.25;"><a href="#CAPITALIZATION">CAPITALIZATION AND INDEBTEDNESS</a></div>
          </td>
          <td style="width: 7.52%; vertical-align: bottom; text-align: center;">10</td>
        </tr>
        <tr>
          <td style="width: 92.48%; vertical-align: top;">
            <div style="line-height: 1.25;"><a href="#SHAREHOLDER">SELLING SHAREHOLDER</a></div>
          </td>
          <td style="width: 7.52%; vertical-align: bottom; text-align: center;">11</td>
        </tr>
        <tr>
          <td style="width: 92.48%; vertical-align: top;">
            <div style="line-height: 1.25;"><a href="#PLAN">PLAN OF DISTRIBUTION</a></div>
          </td>
          <td style="width: 7.52%; vertical-align: bottom; text-align: center;">12</td>
        </tr>
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          <td style="width: 92.48%; vertical-align: top;">
            <div style="line-height: 1.25;"><a href="#ADSs">DESCRIPTION OF OUR ADSs</a></div>
          </td>
          <td style="width: 7.52%; vertical-align: bottom; text-align: center;">14</td>
        </tr>
        <tr>
          <td style="width: 92.48%; vertical-align: top;">
            <div style="line-height: 1.25;"><a href="#TAXATION">TAXATION</a></div>
          </td>
          <td style="width: 7.52%; vertical-align: bottom; text-align: center;">14</td>
        </tr>
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          <td style="width: 92.48%; vertical-align: top;">
            <div style="line-height: 1.25;"><a href="#REPRESENTATIVE">AUTHORIZED REPRESENTATIVE</a></div>
          </td>
          <td style="width: 7.52%; vertical-align: bottom; text-align: center;">14</td>
        </tr>
        <tr>
          <td style="width: 92.48%; vertical-align: top;">
            <div style="line-height: 1.25;"><a href="#EXPENSES">OFFERING EXPENSES</a></div>
          </td>
          <td style="width: 7.52%; vertical-align: bottom; text-align: center;">14</td>
        </tr>
        <tr>
          <td style="width: 92.48%; vertical-align: top;">
            <div style="line-height: 1.25;"><a href="#CHANGES">MATERIAL CHANGES</a></div>
          </td>
          <td style="width: 7.52%; vertical-align: bottom; text-align: center;">14</td>
        </tr>
        <tr>
          <td style="width: 92.48%; vertical-align: top;">
            <div style="line-height: 1.25;"><a href="#MATTERS">LEGAL MATTERS</a></div>
          </td>
          <td style="width: 7.52%; vertical-align: bottom; text-align: center;">14</td>
        </tr>
        <tr>
          <td style="width: 92.48%; vertical-align: top;">
            <div style="line-height: 1.25;"><a href="#EXPERTS">EXPERTS</a></div>
          </td>
          <td style="width: 7.52%; vertical-align: bottom; text-align: center;">14</td>
        </tr>
        <tr>
          <td style="width: 92.48%; vertical-align: top;">
            <div style="line-height: 1.25;"><a href="#INFORMATION">WHERE YOU CAN FIND MORE INFORMATION</a></div>
          </td>
          <td style="width: 7.52%; vertical-align: bottom; text-align: center;">15</td>
        </tr>
        <tr>
          <td style="width: 92.48%; vertical-align: top;">
            <div style="line-height: 1.25;"><a href="#REFERENCE">INCORPORATION OF CERTAIN INFORMATION BY REFERENCE</a></div>
          </td>
          <td style="width: 7.52%; vertical-align: bottom; text-align: center;">15</td>
        </tr>
        <tr>
          <td style="width: 92.48%; vertical-align: top;">
            <div style="line-height: 1.25;"><a href="#LIABILITIES">ENFORCEABILITY OF CIVIL LIABILITIES</a></div>
          </td>
          <td style="width: 7.52%; vertical-align: bottom; text-align: center;">16</td>
        </tr>

    </table>
    <div style="line-height: 1.25;">&#160;</div>
    <div style="text-align: center; line-height: 1.25;">i</div>
    <div style="clear: both; margin-top: 10pt; margin-bottom: 10pt;" class="BRPFPageBreakArea">
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    </div>
    <div style="text-align: justify; text-indent: 36pt; line-height: 1.25;">Unless expressly stated otherwise, in this prospectus, references to &#8220;we&#8221;, &#8220;us&#8221;, &#8220;Trinity Biotech&#8221; or the &#8220;Group&#8221; shall mean Trinity Biotech plc and its world-wide subsidiaries,
      collectively.&#160; References to the &#8220;Company&#8221; shall mean Trinity Biotech plc. All references to &#8220;dollars&#8221; or &#8220;$&#8221; in this prospectus are to U.S. dollars, and all references to &#8220;Euro&#8221; or &#8220;&#8364;&#8221; are to European Union Euro.</div>
    <div style="line-height: 1.25;"><br style="line-height: 1.25;">
    </div>
    <div style="text-align: justify; text-indent: 36pt; line-height: 1.25; font-weight: bold;">You should read this document together with the additional information described under the headings &#8220;Where You Can Find More Information&#8221; and &#8220;Incorporation of
      Certain Information by Reference&#8221; in this prospectus.&#160; We have not authorized any dealer, salesperson or other person to give any information or to make any representation and you should not rely upon any information or representation not contained
      or incorporated by reference in this prospectus.&#160; This prospectus does not constitute an offer to sell or the solicitation of an offer to buy ADSs, nor does this prospectus constitute an offer to sell or the solicitation of an offer to buy ADSs in
      any jurisdiction to any person to whom it is unlawful to make such offer or solicitation in such jurisdiction. You should not assume that the information contained in this prospectus is accurate on any date subsequent to the date set forth on the
      front of the document or that any information we have incorporated by reference is correct on any date subsequent to the date of the document incorporated by reference, even though this prospectus is delivered or ADS is sold on a later date.</div>
    <div style="line-height: 1.25;">&#160;</div>
    <div style="text-align: justify; text-indent: 36pt; line-height: 1.25;">We further note that the representations, warranties and covenants made by us in any agreement that is filed as an exhibit to any document that is incorporated by reference into
      the accompanying prospectus were made solely for the benefit of the parties to such agreement, including, in some cases, for the purpose of allocating risk among the parties to such agreements, and should not be deemed to be a representation,
      warranty or covenant to you. Moreover, such representations, warranties or covenants were accurate only as of the date when made.&#160; Accordingly, such representations, warranties and covenants should not be relied on as accurately representing the
      current state of our affairs.</div>
    <div style="line-height: 1.25;">&#160;</div>
    <div style="text-align: justify; text-indent: 36pt; line-height: 1.25;">This prospectus is not intended to be and is not a prospectus for purposes of: (i) Regulation (EU) 2017/1129 of the European Parliament and of the Council or the European Union
      (Prospectus) Regulations of Ireland 2019; or (ii) Regulation (EU) 2017/1129 as it forms part of United Kingdom domestic law by virtue of the European Union (Withdrawal) Act 2018 of the United Kingdom, as amended by the Prospectus (Amendment etc.) (EU
      Exit) Regulations 2019 of the United Kingdom, or the UK Prospectus Regulation. No offer of shares to the public is made, or will be made, that requires the publication of a prospectus pursuant to European prospectus law or the UK Prospectus
      Regulation. This document has been prepared on the basis that any offer of shares in any relevant European Economic Area member state or the United Kingdom will be made pursuant to an exemption under European prospectus law and the UK Prospectus
      Regulation from the requirement to publish a prospectus for offers of shares and does not constitute an offer or solicitation to anyone to purchase shares in any jurisdiction in which such an offer or solicitation is not authorized nor to any person
      to whom it is unlawful to make such an offer or solicitation. This document has not been reviewed or approved by the Central Bank of Ireland nor by any other competent or supervisory authority of any other member state of the European Economic Area
      or the United Kingdom for the purposes of the EU Prospectus Regulation, or the UK Prospectus Regulation, as applicable. Any representation to the contrary is a criminal offense.</div>
    <div style="line-height: 1.25;">&#160;</div>
    <div style="text-align: center; line-height: 1.25;">ii</div>
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    <div style="text-align: center; line-height: 1.25; font-weight: bold;"><a name="FORWARD"><!--Anchor--></a>FORWARD&#8209;LOOKING STATEMENTS</div>
    <div style="line-height: 1.25;">&#160;</div>
    <div style="text-align: justify; text-indent: 36pt; line-height: 1.25;">Some of the statements contained in this prospectus and the documents incorporated by reference are forward-looking statements. Forward-looking statements involve risks and
      uncertainties, such as statements about our plans, objectives, expectations, assumptions or future events. In some cases, you can identify forward-looking statements by terminology such as &#8220;anticipate,&#8221; &#8220;estimate,&#8221; &#8220;plan,&#8221; &#8220;project,&#8221; &#8220;continuing,&#8221;
      &#8220;ongoing,&#8221; &#8220;expect,&#8221; &#8220;we believe,&#8221; &#8220;we intend,&#8221; &#8220;may,&#8221; &#8220;should,&#8221; &#8220;will,&#8221; &#8220;could&#8221; and similar expressions denoting uncertainty or an action that may, will or is expected to occur in the future. These statements involve estimates, assumptions, known
      and unknown risks, uncertainties and other factors that could cause actual results to differ materially from any future results, performances or achievements expressed or implied by the forward-looking statements. Examples of forward-looking
      statements include, but are not limited to, statements about:</div>
    <div style="line-height: 1.25;"><br style="line-height: 1.25;">
    </div>
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          </td>
          <td style="width: 27pt; vertical-align: top;">&#8226;</td>
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            <div>the development of future products;</div>
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    <div style="line-height: 1.25;">&#160;</div>
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          </td>
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            <div>the potential attributes and benefit of our products and their competitive position;</div>
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    <div style="line-height: 1.25;">&#160;</div>
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          </td>
          <td style="width: 27pt; vertical-align: top;">&#8226;</td>
          <td style="width: auto; vertical-align: top; text-align: justify;">
            <div>our ability to successfully commercialize, or enter into strategic relationships with third parties to commercialize, our products;</div>
          </td>
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    <div style="line-height: 1.25;">&#160;</div>
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          </td>
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            <div>our estimates regarding expenses, future revenues, capital requirements and our need for additional financing;</div>
          </td>
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    <div style="text-align: justify; text-indent: 36pt; line-height: 1.25;">Forward-looking statements are neither historical facts nor assurances of future performance. Instead, they are based only on our current beliefs, expectations and assumptions
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            <div>the extent to which we are successful in gaining new long-term relationships with customers or retaining existing ones;</div>
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            <div>security breaches, cybersecurity attacks and other significant disruptions;</div>
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            <div>natural events such as severe weather, fires, floods and earthquakes or man-made or other disruptions of our business and facilities;</div>
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            <div>strategic actions, including acquisitions and dispositions and our success in integrating acquired businesses; and</div>
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            <div>our ability to obtain and protect rights to the intellectual property necessary for the conduct of our business and the potential costs of enforcing or defending those rights.</div>
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    <div style="text-align: justify; text-indent: 36pt; line-height: 1.25;">The ultimate correctness of these forward-looking statements depends upon a number of known and unknown risks and events. We discuss our known material risks in the section
      entitled &#8220;Risk Factors&#8221; on page 5 of this prospectus and on page 3 in our annual report on Form 20-F for the year ended December 31, 2023 incorporated by reference herein. Many factors could cause our actual results to differ materially from the
      forward-looking statements. In addition, we cannot assess the impact of each factor on our business or the extent to which any factor, or combination of factors, may cause actual results to differ materially from those contained in any
      forward-looking statements.</div>
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    </div>
    <div style="text-align: justify; text-indent: 36pt; line-height: 1.25;">The forward-looking statements speak only as of the date on which they are made, and, except as required by law, we undertake no obligation to update any forward-looking statement
      to reflect events or circumstances after the date on which the statement is made or to reflect the occurrence of unanticipated events.</div>
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    <div style="text-align: center; line-height: 1.25; font-weight: bold;">PROSPECTUS <a name="SUMMARY"><!--Anchor--></a>SUMMARY</div>
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    <div style="text-align: justify; text-indent: 36pt; line-height: 1.25; font-style: italic;">This summary highlights selected information contained elsewhere or incorporated by reference in this prospectus. The summary does not contain all the
      information that you should consider before investing in our ADSs.&#160; You should read the entire prospectus carefully, including &#8220;Risk Factors&#8221; contained in this prospectus and the documents incorporated by reference in this prospectus, before making
      an investment decision. Unless otherwise indicated herein, the terms &#8220;Trinity Biotech,&#8221; the &#8220;Company,&#8221; &#8220;we,&#8221; &#8220;us&#8221; or &#8220;our&#8221; refer to Trinity Biotech plc.</div>
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    </div>
    <div style="text-align: justify; text-indent: 36pt; line-height: 1.25;">We and our subsidiaries develop, acquire, manufacture and market medical diagnostic products and services for the clinical laboratory and point-of-care segments of the diagnostic
      market. These products and services are used to detect and support the management of autoimmune, infectious and sexually transmitted diseases, diabetes and disorders of the liver and intestine.&#160; We have recently entered into the biosensor industry,
      with the acquisition (the &#8220;Waveform Acquisition&#8221;) of the biosensor assets of Waveform Technologies Inc. (&#8220;Waveform&#8221;) and intend to develop a range of biosensor devices and related services, starting with a continuous glucose monitoring (&#8220;CGM&#8221;)
      product.</div>
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    </div>
    <div style="text-align: justify; text-indent: 36pt; line-height: 1.25;">For a full and comprehensive description of our business, markets and product lines, see our most recent Annual Report on Form 20-F and any updates in our Reports of Foreign
      Private Issuer on Form 6-K, to the extent that they are incorporated herein by reference.</div>
    <div style="line-height: 1.25">&#160;</div>
    <div style="text-align: center; margin-right: 0.1pt; margin-left: 0.1pt; line-height: 1.25; font-weight: bold;">Recent Developments</div>
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    </div>
    <div style="text-align: justify; text-indent: 36pt; line-height: 1.25;">
      <div style="text-indent: 36pt; line-height: 1.25; color: #000000; font-family: 'Times New Roman', serif;">In July 2024, we entered into an At the Market Offering Agreement with Craig-Hallum pursuant to which the Company may sell its ADSs from time to
        time in an at the market offering through Craig-Hallum, acting as sales agent (the &#8220;ATM Program&#8221;). As of the date of the registration statement of which this prospectus forms a part, we have issued a total of 4,688,029 ADSs pursuant to the ATM
        Program.</div>
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    <div style="text-align: center; line-height: 1.25; font-weight: bold;">Corporate Information</div>
    <div style="line-height: 1.25;">&#160;</div>
    <div style="text-align: justify; text-indent: 36pt; line-height: 1.25;">
      <div style="text-indent: 36pt; line-height: 1.25; color: #000000; font-family: 'Times New Roman', serif;">We were incorporated as a private limited company registered in Ireland in January 1992 and subsequently re-registered as a public limited
        company (&#8220;plc&#8221;) in July 1992. The Company commenced operations in 1992 and, in October 1992, completed an initial public offering of our securities in the United States. Our principal offices are located at IDA Business Park, Bray, County Wicklow,
        Ireland and our telephone number is +353 1276 9800. Our North American headquarters is based at 2823 Girts Rd., Jamestown, NY 14701, USA.&#160; The Company&#8217;s website is www.trinitybiotech.com. The information in our website is not incorporated by
        reference herein.</div>
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    <div style="text-align: center; line-height: 1.25; font-weight: bold;">THE <a name="OFFERING"><!--Anchor--></a>OFFERING</div>
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            <div style="line-height: 1.25;">ADSs offered by the</div>
            <div style="line-height: 1.25;">selling shareholder&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;</div>
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            <div style="text-align: justify; line-height: 1.25;">
              <div style="line-height: 1.25; color: rgb(0, 0, 0); font-family: 'Times New Roman',serif;">4,290,000 ADSs (each ADS represents 20 A Ordinary Shares, par value $0.0109 per share).&#160; The offered ADSs are evidenced by ADRs.</div>
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            <div style="line-height: 1.25;">&#160;</div>
          </td>
          <td style="width: 50.96%; vertical-align: top;">
            <div style="line-height: 1.25;">&#160;</div>
          </td>
        </tr>
        <tr>
          <td style="width: 49.04%; vertical-align: top;">
            <div style="line-height: 1.25; color: #000000; font-family: 'Times New Roman', serif;">A Ordinary Shares outstanding</div>
            <div style="line-height: 1.25; color: #000000; font-family: 'Times New Roman', serif;">as of March 15, 2025</div>
          </td>
          <td style="width: 50.96%; vertical-align: top;">
            <div style="text-align: justify; line-height: 1.25;">
              <div style="line-height: 1.25; color: rgb(0, 0, 0); font-family: 'Times New Roman',serif;">
                <div style="line-height: 1.25; color: rgb(0, 0, 0);">383,881,600 A Ordinary Shares (which excludes 48,506,672 A Ordinary Shares issuable upon the exercise of options at exercise prices that range from US$0.12-US$1.29 per share, 51,200,000 A
                  Ordinary Shares represented by ADSs issuable upon the exercise of outstanding warrants, and 24,691,358 A Ordinary Shares&#160; represented by ADSs issuable upon conversion of the $20 million convertible note (the &#8220;MiCo Convertible Note&#8221;) held
                  by MiCo IDV Holdings, LLC (&#8220;MiCo&#8221;), with an ADS conversion price of $16.20 per ADS).</div>
              </div>
            </div>
          </td>
        </tr>
        <tr>
          <td style="width: 49.04%; vertical-align: top;">
            <div style="line-height: 1.25;">&#160;</div>
          </td>
          <td style="width: 50.96%; vertical-align: top;">
            <div style="line-height: 1.25;">&#160;</div>
          </td>
        </tr>
        <tr>
          <td style="width: 49.04%; vertical-align: top;">
            <div style="line-height: 1.25;">Use of proceeds&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;</div>
          </td>
          <td style="width: 50.96%; vertical-align: top;">
            <div style="text-align: justify; line-height: 1.25;">
              <div style="line-height: 1.25; color: rgb(0, 0, 0); font-family: 'Times New Roman',serif;">We will not receive any proceeds from the sale of the ADSs offered hereby except that we may receive up to $2,000,000 upon the exercise of the
                Warrants.</div>
            </div>
          </td>
        </tr>
        <tr>
          <td style="width: 49.04%; vertical-align: top;">
            <div style="line-height: 1.25;">&#160;</div>
          </td>
          <td style="width: 50.96%; vertical-align: top;">
            <div style="line-height: 1.25;">&#160;</div>
          </td>
        </tr>
        <tr>
          <td style="width: 49.04%; vertical-align: top;">
            <div style="line-height: 1.25;">NASDAQ Capital Market symbol&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;</div>
          </td>
          <td style="width: 50.96%; vertical-align: top;">
            <div style="text-align: justify; line-height: 1.25;">&#8220;TRIB&#8221;</div>
          </td>
        </tr>
        <tr>
          <td style="width: 49.04%; vertical-align: top;">
            <div style="line-height: 1.25;">&#160;</div>
          </td>
          <td style="width: 50.96%; vertical-align: top;">
            <div style="line-height: 1.25;">&#160;</div>
          </td>
        </tr>
        <tr>
          <td style="width: 49.04%; vertical-align: top;">
            <div style="line-height: 1.25;">Risk Factors&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;</div>
          </td>
          <td style="width: 50.96%; vertical-align: top;">
            <div style="text-align: justify; line-height: 1.25;">Prospective investors should carefully consider the Risk Factors beginning on Page 5 and under similar headings in the other documents that are incorporated by reference into this prospectus
              for a discussion of certain factors that should be considered before buying the ADSs offered hereby.</div>
          </td>
        </tr>

    </table>
    <div style="line-height: 1.25;"><br style="line-height: 1.25;">
    </div>
    <div style="clear: both; margin-top: 10pt; margin-bottom: 10pt;" class="BRPFPageBreakArea">
      <div class="BRPFPageNumberArea" style="text-align: center;"><font class="BRPFPageNumber" style="font-weight: normal; font-style: normal;">4</font></div>
      <div style="page-break-after: always;" class="BRPFPageBreak">
        <hr noshade="noshade" style="margin: 4px 0px; width: 100%; border-width: 0; height: 2px; color: #000000; background-color: #000000; clear: both;"></div>
    </div>
    <div style="text-align: center; line-height: 1.25; font-weight: bold;"><a name="RISK"><!--Anchor--></a>RISK FACTORS</div>
    <div style="line-height: 1.25;">&#160;</div>
    <div style="text-align: justify; text-indent: 36pt; line-height: 1.25; font-style: italic;">Investing in our securities involves significant risks. Please see the risk factors under the heading &#8220;Risk Factors&#8221; in our most recent Annual Report on Form
      20-F on file with the Commission, as revised or supplemented by our reports subsequently filed after the date hereof with the Commission and incorporated by reference in this prospectus. Before making an investment decision, you should carefully
      consider these risks as well as other information we include or incorporate by reference in this prospectus. The risks and uncertainties we have described are not the only ones facing our company. Additional risks and uncertainties not presently
      known to us or that we currently deem immaterial may also affect our business operations. The occurrence of any of these risks might cause you to lose all or part of your investment in the offered securities. The discussion of risks includes or
      refers to forward-looking statements; you should read the explanation of the qualifications and limitations on such forward-looking statements discussed elsewhere in this.</div>
    <div style="line-height: 1.25;">&#160;</div>
    <div style="text-align: justify; line-height: 1.25; font-weight: bold;">Risks Related to Ownership of our ADSs</div>
    <div style="line-height: 1.25;"><br style="line-height: 1.25;">
    </div>
    <div style="text-align: justify; line-height: 1.25; font-style: italic; font-weight: bold;">We may encounter difficulties in realizing the potential financial or strategic benefits of recent business acquisitions. We expect to make additional
      acquisitions in the future that could disrupt our operations and harm our operating results.</div>
    <div style="line-height: 1.25">&#160;</div>
    <div style="text-align: justify; text-indent: 35.9pt; margin-left: 0.1pt; line-height: 1.25;">
      <div style="text-indent: 36pt; line-height: 1.25; color: #000000; font-family: 'Times New Roman', serif;">
        <div style="text-indent: 36pt; line-height: 1.25; color: #000000;">A significant part of our business strategy is to pursue acquisitions and other initiatives based on a strategy centered on adding complementary solutions to our portfolio&#8212;all while
          we seek to ensure our continued high quality of services and product delivery. We have made numerous acquisitions including the acquisition in 2024 of the biosensor assets of Waveform and intend to develop a range of biosensor devices and related
          services, starting with a continuous glucose monitoring (&#8220;CGM&#8221;) product.</div>
      </div>
    </div>
    <div style="line-height: 1.25">&#160;</div>
    <div style="text-align: justify; text-indent: 35.8pt; margin-right: 0.1pt; margin-left: 0.3pt; line-height: 1.25;">Mergers and acquisitions of companies and assets are inherently risky and subject to many factors outside of our control and no assurance
      can be given that our future acquisitions will be successful and will not adversely affect our business, operating results, or financial condition. In the future, we may seek to acquire or make strategic investments in complementary businesses,
      technologies, services or products, or enter into strategic partnerships or alliances with third parties in order to expand our business. Failure to manage and successfully integrate such acquisitions could materially harm our business and operating
      results. Prior acquisitions have resulted in a wide range of outcomes, from successful introduction of new products technologies and professional services to a failure to do so. There can be no assurance that new product enhancements will be made in
      a timely manner or that pre-acquisition due diligence will have identified all possible issues that might arise with respect to such products. If we acquire other businesses, we may face difficulties, including:</div>
    <div style="line-height: 1.25">&#160;</div>
    <table cellspacing="0" cellpadding="0" style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;" class="DSPFListTable" id="z396bf99eb605458e9087fcd4c1c75426">

        <tr>
          <td style="width: 54.3pt;"><br>
          </td>
          <td style="width: 18pt; vertical-align: top;">&#8226;</td>
          <td style="width: auto; vertical-align: top; text-align: justify;">
            <div>Difficulties in integrating the operations, systems, technologies, products, and personnel of the acquired businesses or enterprises;</div>
          </td>
        </tr>

    </table>
    <div style="line-height: 1.25">&#160;</div>
    <table cellspacing="0" cellpadding="0" style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;" class="DSPFListTable" id="z263e0c0831404bfc8c4a7697dcbeec2a">

        <tr>
          <td style="width: 54.4pt;"><br>
          </td>
          <td style="width: 18pt; vertical-align: top;">&#8226;</td>
          <td style="width: auto; vertical-align: top; text-align: justify;">
            <div>Diversion of management&#8217;s attention from normal daily operations of the business and the challenges of managing larger and more widespread operations resulting from acquisitions;</div>
          </td>
        </tr>

    </table>
    <div style="line-height: 1.25">&#160;</div>
    <table cellspacing="0" cellpadding="0" style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;" class="DSPFListTable" id="z09078311158e425f89441927e79d55b1">

        <tr>
          <td style="width: 54.5pt;"><br>
          </td>
          <td style="width: 18pt; vertical-align: top;">&#8226;</td>
          <td style="width: auto; vertical-align: top; text-align: justify;">
            <div>Integrating financial forecasting and controls, procedures and reporting cycles;</div>
          </td>
        </tr>

    </table>
    <div style="line-height: 1.25">&#160;</div>
    <table cellspacing="0" cellpadding="0" style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;" class="DSPFListTable" id="z31d51fc8d05e44b9a4e2ca46c4159876">

        <tr>
          <td style="width: 54.6pt;"><br>
          </td>
          <td style="width: 18pt; vertical-align: top;">&#8226;</td>
          <td style="width: auto; vertical-align: top; text-align: justify;">
            <div>Potential difficulties in completing projects associated with in-process research and development;</div>
          </td>
        </tr>

    </table>
    <div style="line-height: 1.25">&#160;</div>
    <table cellspacing="0" cellpadding="0" style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;" class="DSPFListTable" id="zd27adcba9ef24bfea81942b81e60e4fd">

        <tr>
          <td style="width: 54.7pt;"><br>
          </td>
          <td style="width: 18pt; vertical-align: top;">&#8226;</td>
          <td style="width: auto; vertical-align: top; text-align: justify;">
            <div>Difficulties in entering markets in which we have no or limited direct prior experience and where competitors in such markets have stronger market positions;</div>
          </td>
        </tr>

    </table>
    <div style="line-height: 1.25">&#160;</div>
    <table cellspacing="0" cellpadding="0" style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;" class="DSPFListTable" id="z327a650f8dbb4b349e36e2493cea8a46">

        <tr>
          <td style="width: 54.8pt;"><br>
          </td>
          <td style="width: 18pt; vertical-align: top;">&#8226;</td>
          <td style="width: auto; vertical-align: top; text-align: justify;">
            <div>Insufficient revenue to offset increased expenses associated with acquisitions; and</div>
          </td>
        </tr>

    </table>
    <div style="line-height: 1.25">&#160;</div>
    <table cellspacing="0" cellpadding="0" style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;" class="DSPFListTable" id="z2440b96956d14c7dbab36b955c8e1a3f">

        <tr>
          <td style="width: 54.8pt;"><br>
          </td>
          <td style="width: 18pt; vertical-align: top;">&#8226;</td>
          <td style="width: auto; vertical-align: top; text-align: justify;">
            <div>The potential loss of key employees, customers, distributors, vendors and other business partners of the companies we acquire following and continuing after announcement of acquisition plans</div>
          </td>
        </tr>

    </table>
    <div style="line-height: 1.25">&#160;</div>
    <div class="BRPFPageBreakArea" style="clear: both; margin-top: 10pt; margin-bottom: 10pt;">
      <div class="BRPFPageNumberArea" style="text-align: center;"><font class="BRPFPageNumber" style="font-weight: normal; font-style: normal;">5</font></div>
      <div class="BRPFPageBreak" style="page-break-after: always;">
        <hr noshade="noshade" style="border-width: 0px; clear: both; margin: 4px 0px; width: 100%; height: 2px; color: #000000; background-color: #000000;"></div>
    </div>
    <div style="line-height: 1.25; font-style: italic; font-weight: bold; text-align: justify;">We may not succeed in our efforts to implement a comprehensive transformation plan to improve the financial performance of our existing business and realign our
      continuing business.</div>
    <div style="line-height: 1.25; font-style: italic; font-weight: bold;"> <br>
    </div>
    <div style="line-height: 1.25;">We initially announced the adoption of a transformation plan to improve the financial performance of our existing business in April 2024 and we continue to pursue a strategic realignment of our continuing business. The
      plan has several key components, including:</div>
    <div style="line-height: 1.25;"><br style="line-height: 1.25;">
    </div>
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        <tr>
          <td style="width: 18pt;"><br>
          </td>
          <td style="width: 18pt; vertical-align: top;">&#8226;</td>
          <td style="width: auto; vertical-align: top;">
            <div>Reducing complexity and cost by consolidating our main manufacturing operations into a considerably smaller number of sites and also moving to an outsourced model for a significant amount of our less complex manufacturing activities;</div>
          </td>
        </tr>

    </table>
    <div style="line-height: 1.25;"><br style="line-height: 1.25;">
    </div>
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        <tr>
          <td style="width: 18pt;"><br>
          </td>
          <td style="width: 18pt; vertical-align: top;">&#8226;</td>
          <td style="width: auto; vertical-align: top;">
            <div>Reducing the cost of goods of many of our products by changing suppliers and negotiating new deals with existing suppliers;</div>
          </td>
        </tr>

    </table>
    <div style="line-height: 1.25;"><br style="line-height: 1.25;">
    </div>
    <table cellspacing="0" cellpadding="0" style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;" class="DSPFListTable" id="z29bdc8fe44e74f6dbf34d10eb3540ff9">

        <tr>
          <td style="width: 18pt;"><br>
          </td>
          <td style="width: 18pt; vertical-align: top;">&#8226;</td>
          <td style="width: auto; vertical-align: top;">
            <div>Continued market acceptance of our new TrinScreen&#8482; HIV rapid point-of-care test;</div>
          </td>
        </tr>

    </table>
    <div style="line-height: 1.25;"><br style="line-height: 1.25;">
    </div>
    <table cellspacing="0" cellpadding="0" style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;" class="DSPFListTable" id="z6644d08d65d54100aed7cf469a8127a8">

        <tr>
          <td style="width: 18pt;"><br>
          </td>
          <td style="width: 18pt; vertical-align: top;">&#8226;</td>
          <td style="width: auto; vertical-align: top;">
            <div>Simplifying our internal operations and optimizing our business support function locations; and</div>
          </td>
        </tr>

    </table>
    <div style="line-height: 1.25;"><br style="line-height: 1.25;">
    </div>
    <table cellspacing="0" cellpadding="0" style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;" class="DSPFListTable" id="zf6516ee332ff4b3d8c97b60b8373cc64">

        <tr>
          <td style="width: 18pt;"><br>
          </td>
          <td style="width: 18pt; vertical-align: top;">&#8226;</td>
          <td style="width: auto; vertical-align: top;">
            <div>Realigning our existing business portfolio to support our planned growth in the CGM space.</div>
          </td>
        </tr>

    </table>
    <div style="line-height: 1.25;"><br style="line-height: 1.25;">
    </div>
    <div style="line-height: 1.25;">&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;Although we have implemented or are in the final stages of implementing a number of cost-saving initiatives, including consolidating manufacturing, moving some manufacturing offshore to improve our operating
      margins, and moving significant aspects of our business support functions to a lower cost and centralized location, we cannot assure you that these efforts will be successful or that we can achieve our realignment and long-term profitability goals. A
      failure to achieve these goals will have a material adverse effect on our results of operations and financial condition.</div>
    <div style="line-height: 1.25;"><br style="line-height: 1.25;">
    </div>
    <div style="line-height: 1.25; font-style: italic; font-weight: bold; text-align: justify;">In 2021, certain of our U.S. subsidiaries received loans which were subsequently forgiven under the Paycheck Protection Program under the&#160;Coronavirus Aid,
      Relief, and Economic Security Act (the &#8220;CARES Act&#8221;) which they may not have been eligible to receive. If it is determined that the subsidiaries were ineligible to receive the loans, they may be required to return the proceeds, pay interest and may be
      subject to other penalties.</div>
    <div style="line-height: 1.25;"><br style="line-height: 1.25;">
    </div>
    <div style="text-indent: 36pt; line-height: 1.25; text-align: justify;">In January&#160;2021, two of our U.S. based subsidiaries applied for and received loans totaling approximately $1.8 million&#160;under the Paycheck Protection Program (the &#8220;PPP&#8221;) of
      the&#160;CARES Act. In September 2021, the two subsidiaries applied for forgiveness of the loans and those loans were subsequently forgiven. While our subsidiaries believed at the time that they obtained the loans that they met all of the eligibility
      requirements under the CARES Act, they were notified by the Department of Justice in late October 2024 that the two subsidiaries may have not been eligible to receive those loans. We voluntarily conducted an internal review of the circumstances
      surrounding the loan process and have made a preliminary determination that due to changes in the guidelines for such loans, the two subsidiaries may have inadvertently not met the headcount eligibility criteria. During a January 28, 2025
      videoconference among outside U.S. Counsel engaged to respond to questions from the Civil Division of the Department of Justice about the aforementioned loans obtained by the two US. Subsidiaries, a lawyer employed by the Department of Justice
      raised, for the first time with the Company, the question of whether its U.S. subsidiaries met the headcount eligibility criteria for the first round of PPP loans in 2020, when the subsidiaries received approximately $4 million of loans which were
      subsequently forgiven. The criteria for eligibility was different for the two rounds of loans, and we believe that the U.S. subsidiaries met the eligibility criteria for the first round of loans based on guidance issued by the Small Business
      Administration at the time of the first round of loan applications and as a result of having a lower headcount arising from furloughs of employees that were not expected to be rehired. We, along with our legal counsel, have reviewed the circumstances
      surrounding the initial PPP loans. We have also communicated with the Department of Justice through a letter, outlining the reasons for our eligibility and await a response. If the U.S. subsidiaries were not eligible for those loans, the Company will
      likely be required to return the proceeds of those loans, pay interest, and may be subject to enforcement proceedings. This may result in adverse publicity and damage to our reputation and have a material adverse effect on our results of operations
      and financial condition.</div>
    <div style="line-height: 1.25;"><br style="line-height: 1.25;">
    </div>
    <div class="BRPFPageBreakArea" style="clear: both; margin-top: 10pt; margin-bottom: 10pt;">
      <div class="BRPFPageNumberArea" style="text-align: center;"><font class="BRPFPageNumber" style="font-weight: normal; font-style: normal;">6</font></div>
      <div class="BRPFPageBreak" style="page-break-after: always;">
        <hr noshade="noshade" style="border-width: 0px; clear: both; margin: 4px 0px; width: 100%; height: 2px; color: #000000; background-color: #000000;"></div>
    </div>
    <div style="line-height: 1.25; font-style: italic; font-weight: bold;">The Nasdaq Global Select Market imposes listing standards on our ADSs that we may not be able to fulfill in the future, thereby leading to a possible delisting of our ADSs.</div>
    <div style="line-height: 1.25; font-style: italic; font-weight: bold;"> <br>
    </div>
    <div style="text-indent: 36pt; line-height: 1.25; text-align: justify;">As a listed Nasdaq Global Select Market company, we are subject to various listing standards.&#160; There can be no assurance that we will be able to meet all of the criteria necessary
      for Nasdaq to allow our ADSs to remain listed.</div>
    <div style="line-height: 1.25;"><br style="line-height: 1.25;">
    </div>
    <div style="text-indent: 36pt; line-height: 1.25; text-align: justify;">On March 19, 2025, we received two deficiency letters from the Listing Qualifications Department of Nasdaq (the &#8220;Staff&#8221;). One deficiency letter notified us that we are not in
      compliance with the minimum market value of publicly held shares (&#8220;MVPHS&#8221;) requirement of the Nasdaq Listing Rules applicable to companies listed on the Nasdaq Global Select Market. For continued listing, companies are required to maintain a minimum
      MVPHS of $15 million. A failure to meet the minimum MVPHS requirement exists if the deficiency continues for a period of 30 consecutive business days. The other deficiency letter notified us that for the preceding 30 consecutive business days, the
      ADSs did not maintain a minimum closing bid price of $1.00 (the &#8220;Minimum Bid Price&#8221;) per ADS, as required by Nasdaq Listing Rule 5450(a)(1).</div>
    <div style="line-height: 1.25;"><br style="line-height: 1.25;">
    </div>
    <div style="text-indent: 36pt; line-height: 1.25; text-align: justify;">In accordance with the Nasdaq Listing Rules, we have 180 calendar days from the date of the deficiency notices, or until September 10, 2025, to regain compliance with the minimum
      MVPHS requirement and the Minimum Bid Price requirement.</div>
    <div style="line-height: 1.25;"><br style="line-height: 1.25;">
    </div>
    <div style="text-indent: 36pt; line-height: 1.25; text-align: justify;">To regain compliance with the MVPHS requirement, the Company&#8217;s MVPHS must exceed $15 million for a minimum of ten consecutive business days. If the Company does not regain
      compliance with the minimum MVPHS requirement by September 10, 2025, Nasdaq will provide written notification to the Company that its ADSs are subject to delisting. At that time, the Company may appeal the relevant delisting determination to a
      hearings panel pursuant to the procedures set forth in the applicable Nasdaq Listing Rules; however, there can be no assurance that the Company will satisfy the minimum MVPHS requirement or that any such appeal would be successful.</div>
    <div style="line-height: 1.25;"><br style="line-height: 1.25;">
    </div>
    <div style="text-indent: 36pt; line-height: 1.25; text-align: justify;">To regain compliance with the Minimum Bid Price requirement, the closing bid price of the Company&#8217;s ADSs must meet or exceed US $1.00 for at least ten consecutive business days
      during the 180-calendar day cure period. In the event the Company does not regain compliance with the Minimum Bid Price Requirement in that period, we may be eligible for an additional 180 calendar day grace period if we meet the continued listing
      requirement for MVPHS and all other initial listing standards for The Nasdaq Capital Market, with the exception of the bid price and provide written notice to the Staff of our intention to cure the deficiency during the second compliance
      period.&#160;However, if it appears to the Staff that we will not be able to cure the deficiency, or if we are otherwise not eligible, Nasdaq will provide notice to us that our ADSs will be subject to delisting.</div>
    <div style="line-height: 1.25;"><br style="line-height: 1.25;">
    </div>
    <div style="text-indent: 36pt; line-height: 1.25; text-align: justify;">If our ADSs are ultimately delisted from Nasdaq and we are unable to successfully transfer the listing of our ADSs to The Nasdaq Capital Market, our ADSs would likely then trade
      only in the over-the-counter market and the market liquidity of our ADSs could be adversely affected and their market price could decrease. If our ADSs were to trade on the over-the-counter market, selling our ADSs could be more difficult because
      smaller quantities of shares would likely be bought and sold, transactions could be delayed, and we could face significant material adverse consequences, including: a limited availability of market quotations for our securities; reduced liquidity
      with respect to our securities; a determination that our shares are a &#8220;penny stock,&#8221; which will require brokers trading in our securities to adhere to more stringent rules, possibly resulting in a reduced level of trading activity in the secondary
      trading market for our securities; a reduced amount of news and analyst coverage for our Company; and a decreased ability to issue additional securities or obtain additional financing in the future. These factors could result in lower prices and
      larger spreads in the bid and ask prices for our ADSs and would substantially impair our ability to raise additional funds and could result in a loss of institutional investor interest and fewer development opportunities for us.</div>
    <div style="line-height: 1.25;"><br style="line-height: 1.25;">
    </div>
    <div class="BRPFPageBreakArea" style="clear: both; margin-top: 10pt; margin-bottom: 10pt;">
      <div class="BRPFPageNumberArea" style="text-align: center;"><font class="BRPFPageNumber" style="font-weight: normal; font-style: normal;">7</font></div>
      <div class="BRPFPageBreak" style="page-break-after: always;">
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    </div>
    <div style="line-height: 1.25; font-weight: bold; text-align: justify;"><font style="font-style: italic;">We have incurred substantial debt, which could impair our flexibility and access to capital and adversely affect our financial position</font>.</div>
    <div style="line-height: 1.25; font-weight: bold;"> <br>
    </div>
    <div style="text-indent: 36pt; line-height: 1.25;">
      <div style="text-indent: 36pt; line-height: 1.25; color: #000000; font-family: 'Times New Roman', serif;">
        <div style="text-align: justify; text-indent: 36pt; line-height: 1.25; color: rgb(0, 0, 0); font-family: 'Times New Roman',serif;">As of December 31, 2024, we had total indebtedness of approximately US$83.4 million (carrying value under IFRS),
          consisting of a senior secured term loan (the &#8220;Term Loan&#8221;) from Perceptive, a convertible note, a derivative liability related to warrants issued to Perceptive, lease liabilities and a residual amount owing for an exchangeable note which was
          almost completely retired in 2022. The Term Loan, which is repayable in January 2026, had a principal outstanding amount of US$75.5 million as of December 31, 2024. In connection with the third amendment and restatement of the credit agreement
          governing the Term Loan on December 23, 2024, we agreed that certain interest payments payable in 2024 and 2025 would be paid-in-kind on the applicable payment date by increasing the outstanding principal amount of the Term Loan.&#160; On February 27,
          2025, we entered into the fourth amended and restated credit agreement, which provided for an additional US$4.0 million increase to our outstanding Term Loan. In addition, a deferred consideration payment of $5.0 million related to the
          acquisition of the biosensor assets of Waveform has been extended to November 2025.</div>
      </div>
    </div>
    <div style="line-height: 1.25;"><br style="line-height: 1.25;">
    </div>
    <div style="text-indent: 36pt; line-height: 1.25; text-align: justify;">The convertible note, which was issued to MiCo and has a nominal outstanding amount of US$20.0 million, mandatorily converts into ADSs if the volume weighted average price of the
      Company&#8217;s ADSs is at or above US$16.20 for any five consecutive trading days. The convertible note shall become immediately repayable at par together with any accrued interest, if the Company or any of its material subsidiaries ceases or threatens to
      cease carrying on its business or a part of its business which is material to the Group, however, subject to the terms of an Investor Subordination Agreement between Perceptive and MiCo, MiCo shall not, without the prior written consent of
      Perceptive, take any enforcement action with respect to the convertible note. Such enforcement actions include, inter alia, any MiCo action to enforce payment of or to collect the whole or any part of the convertible note.</div>
    <div style="line-height: 1.25;"><br style="line-height: 1.25;">
    </div>
    <div style="text-indent: 36pt; line-height: 1.25; text-align: justify;">As a result of the debt we have incurred, we may need to raise capital in one or more debt or equity offerings to fund our operations and obligations. There can be no assurance,
      however, that we will be successful in raising the necessary capital or that any such offering will be available to us on terms acceptable to us, or at all. If we are unable to raise additional capital that may be needed on terms in sufficient
      amounts or on terms acceptable to us, it could have a material adverse effect on our company and we may have to significantly delay, scale back or discontinue our deliveries under our outstanding customer purchase orders or the development or
      commercialization of one or more of our products or one or more of our other research and development initiatives, sell assets and/or cease trading.</div>
    <div style="line-height: 1.25;"><br style="line-height: 1.25;">
    </div>
    <div style="text-indent: 18pt; line-height: 1.25;">Our debt may:</div>
    <div style="line-height: 1.25;"><br style="line-height: 1.25;">
    </div>
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        <tr>
          <td style="width: 18pt;"><br>
          </td>
          <td style="width: 18pt; vertical-align: top;">&#8226;</td>
          <td style="width: auto; vertical-align: top;">
            <div>require us to use a substantial portion of our cash flow from operations to make debt service payments;</div>
          </td>
        </tr>

    </table>
    <div style="line-height: 1.25">&#160;</div>
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        <tr>
          <td style="width: 18pt;"><br>
          </td>
          <td style="width: 18pt; vertical-align: top;">&#8226;</td>
          <td style="width: auto; vertical-align: top;">
            <div>limit our ability to use our cash flow or obtain additional financing for working capital, capital expenditures, acquisitions or other general business purposes;</div>
          </td>
        </tr>

    </table>
    <div style="line-height: 1.25">&#160;</div>
    <table cellspacing="0" cellpadding="0" style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;" class="DSPFListTable" id="z987a4df6da974179a1ed754c6796da5a">

        <tr>
          <td style="width: 18pt;"><br>
          </td>
          <td style="width: 18pt; vertical-align: top;">&#8226;</td>
          <td style="width: auto; vertical-align: top;">
            <div>limit our flexibility to plan for, or react to, changes in our business and industry;</div>
          </td>
        </tr>

    </table>
    <div style="line-height: 1.25">&#160;</div>
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        <tr>
          <td style="width: 18pt;"><br>
          </td>
          <td style="width: 18pt; vertical-align: top;">&#8226;</td>
          <td style="width: auto; vertical-align: top;">
            <div>result in dilution to our existing shareholders in the event we issue equity to fund our debt obligations;</div>
          </td>
        </tr>

    </table>
    <div style="line-height: 1.25">&#160;</div>
    <table cellspacing="0" cellpadding="0" style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;" class="DSPFListTable" id="z4b31411df89c43afbc1da0c774e8800d">

        <tr>
          <td style="width: 18pt;"><br>
          </td>
          <td style="width: 18pt; vertical-align: top;">&#8226;</td>
          <td style="width: auto; vertical-align: top;">
            <div>place us at a competitive disadvantage compared to our less leveraged competitors; and</div>
          </td>
        </tr>

    </table>
    <div style="line-height: 1.25">&#160;</div>
    <table cellspacing="0" cellpadding="0" style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;" class="DSPFListTable" id="z2823499e33684eac947c4ea07c3e3c75">

        <tr>
          <td style="width: 18pt;"><br>
          </td>
          <td style="width: 18pt; vertical-align: top;">&#8226;</td>
          <td style="width: auto; vertical-align: top;">
            <div>increase our vulnerability to the impact of adverse economic and industry conditions.</div>
          </td>
        </tr>

    </table>
    <div style="line-height: 1.25;"><br style="line-height: 1.25;">
    </div>
    <div style="text-indent: 36pt; line-height: 1.25; text-align: justify;">To the extent we are unable to repay our debt as it becomes due with cash on hand or from other sources, we will need to refinance our debt, sell assets or repay the debt with the
      proceeds from equity offerings in order to continue in business. Additional indebtedness or equity financing may not be available to us in the future for the refinancing or repayment of existing debt, or if available, such additional debt or equity
      financing may not be available on a timely basis, or on terms acceptable to us and within the limitations specified in our then existing debt instruments. In addition, in the event we decide to sell additional assets, we can provide no assurance as
      to the timing of any asset sales or the proceeds that could be realized by us from any such asset sale. Our ability to obtain additional funding may determine our ability to continue as a going concern.</div>
    <div style="line-height: 1.25;"><br style="line-height: 1.25;">
    </div>
    <div class="BRPFPageBreakArea" style="clear: both; margin-top: 10pt; margin-bottom: 10pt;">
      <div class="BRPFPageNumberArea" style="text-align: center;"><font class="BRPFPageNumber" style="font-weight: normal; font-style: normal;">8</font></div>
      <div class="BRPFPageBreak" style="page-break-after: always;">
        <hr noshade="noshade" style="border-width: 0px; clear: both; margin: 4px 0px; width: 100%; height: 2px; color: #000000; background-color: #000000;"></div>
    </div>
    <div style="line-height: 1.25; font-style: italic; font-weight: bold; text-align: justify;">Certain of our customers are dependent on continued U.S. government funding, which may not be made on a timely basis or at all and such funding cuts or delays
      could have an adverse effect on our business.</div>
    <div style="line-height: 1.25; font-style: italic; font-weight: bold;"> <br>
    </div>
    <div style="text-indent: 36pt; line-height: 1.25;">
      <div style="text-align: justify; text-indent: 36pt; line-height: 1.25; color: rgb(0, 0, 0); font-family: 'Times New Roman',serif;">
        <div style="text-indent: 36pt; line-height: 1.25; color: #000000; font-family: 'Times New Roman', serif;">The Company is continuously monitoring the potential impact of the U.S. President&#8217;s Executive Order on Reevaluating and Realigning United
          States Foreign Aid, and resulting suspensions or termination of funding to HIV testing programs that utilize the Company&#8217;s two rapid HIV tests. On January 20, 2025, the U.S. government paused, subject to certain exemptions, all new funding
          obligations and sub-obligations of funding of foreign assistance programs, pending a 90-day review of such foreign assistance programs. Although the U.S. government introduced a temporary waiver of the aforementioned funding pause for certain
          assistance, which the U.S. government later confirmed applied to funding for HIV testing under the President's Emergency Plan for AIDS Relief (PEPFAR), that waiver is temporary, and there can be no assurance that U.S. government funding for HIV
          programs that utilize the Company&#8217;s rapid HIV tests will continue. Since the Executive Order, the Company has seen disruptions to ordering patterns and demand for our rapid HIV tests, and it remains unclear at this time what impact these changes
          will have on the timing and quantity of rapid HIV tests sold by the Company, and the receipt of funds for the sale of such tests.</div>
      </div>
    </div>
    <div style="line-height: 1.25;"><br style="line-height: 1.25;">
    </div>
    <div style="text-align: justify; line-height: 1.25; font-weight: bold;">Risks Related to the Offering</div>
    <div style="line-height: 1.25;"><br style="line-height: 1.25;">
    </div>
    <div style="text-align: justify; text-indent: 36pt; line-height: 1.25; font-weight: bold;">Sales of ADSs held by Perceptive and the additional ADSs issuable upon exercise of the Warrants may cause the market price of our ADSs to decline.</div>
    <div style="line-height: 1.25;"><br style="line-height: 1.25;">
    </div>
    <div style="text-align: justify; text-indent: 36pt; line-height: 1.25;">
      <div style="text-indent: 36pt; line-height: 1.25; color: #000000; font-family: 'Times New Roman', serif;">Perceptive holds 1.79 million ADSs; and Perceptive&#8217;s Warrants entitle it to purchase up to an additional 2.5 million ADSs, representing, in the
        aggregate, 85.8 million of our A Ordinary Shares. The sale of those ADSs, or the perception that such sales could occur, may cause the market price of our ADSs to decline or become more volatile. In addition, the fact that Perceptive can sell
        substantial amounts of ADSs in the public market, whether or not sales have occurred or are occurring, could make it more difficult for the Company to raise additional financing through the sale of equity or equity-related securities in the future
        at a time and price that it deems reasonable or appropriate.</div>
    </div>
    <div style="line-height: 1.25;"><br style="line-height: 1.25;">
    </div>
    <div style="clear: both; margin-top: 10pt; margin-bottom: 10pt;" class="BRPFPageBreakArea">
      <div class="BRPFPageNumberArea" style="text-align: center;"><font class="BRPFPageNumber" style="font-weight: normal; font-style: normal;">9</font></div>
      <div style="page-break-after: always;" class="BRPFPageBreak">
        <hr noshade="noshade" style="margin: 4px 0px; width: 100%; border-width: 0; height: 2px; color: #000000; background-color: #000000; clear: both;"></div>
    </div>
    <div style="text-align: center; line-height: 1.25; font-weight: bold;">USE OF <a name="PROCEEDS"><!--Anchor--></a>PROCEEDS</div>
    <div style="line-height: 1.25;">&#160;</div>
    <div style="text-align: justify; text-indent: 36pt; line-height: 1.25;">We will not receive the proceeds from the resale of the ADSs by Perceptive. We may receive up to an aggregate of $2,000,000 from the exercise of the Warrants, assuming the exercise
      in full of the Warrants. Any proceeds from the exercise of the Warrants will be used for working capital and general corporate purposes.</div>
    <div style="line-height: 1.25;">&#160;</div>
    <div style="text-align: center; line-height: 1.25; font-weight: bold;"><a name="CAPITALIZATION"><!--Anchor--></a>CAPITALIZATION AND INDEBTEDNESS</div>
    <div style="line-height: 1.25;">&#160;</div>
    <div style="text-align: justify; text-indent: 36pt; line-height: 1.25;">The following table sets forth our capitalization and indebtedness as of September 30, 2024, as derived from our financial statements, which are prepared in accordance with
      International Financial Reporting Standards, as issued by the International Accounting Standards Board. The information in this table should be read in conjunction with the financial statements and notes thereto and other financial information
      incorporated by reference into this prospectus and any prospectus supplement.</div>
    <div style="line-height: 1.25;"><br style="line-height: 1.25;">
    </div>
    <div style="text-align: justify; text-indent: 36pt; line-height: 1.25;">
      <div style="text-indent: 36pt; line-height: 1.25; color: #000000; font-family: 'Times New Roman', serif;">The table below presents our capitalization and indebtedness on an actual basis and on an as-adjusted basis to give effect to (A) (i) the
        issuance of 1,730,603 ADSs in connection with the acquisition of Epicapture Limited on October 22, 2024, (ii) the issuance of 1,399,985 ADSs on October 10, 2024 in connection with our investment in Novus Diagnostics, (iii) the issuance of 361,892
        ADSs to Native Design Limited on October 10, 2024 pursuant to a design services agreement, (iv) the issuance of 650,000 ADSs to Craig Hallum on October 10, 2024 pursuant to an advisory agreement, (v) to capitalization of certain paid-in-kind
        interest payments pursuant to the third amendment and restatement of the credit agreement governing the Term Loan, (vi) the issuance of 1,343,821 ADSs pursuant to the ATM Program from October 1, 2024 through March 21, 2025, and (B) the Fourth
        Amendment Borrowing, in each case as if they had occurred on September 30, 2024.</div>
    </div>
    <div style="line-height: 1.25;">&#160;</div>
    <table cellspacing="0" cellpadding="0" class="cfttable" id="ze9dbc8a7f74e44bf8b54b49f2aea7a28" style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; text-align: left; color: #000000; width: 100%;">

        <tr>
          <td valign="bottom" style="vertical-align: top; padding-bottom: 2px;">
            <div style="line-height: 1.25;">&#160;</div>
          </td>
          <td valign="bottom" class="cftguttercell" colspan="1" style="vertical-align: bottom; padding-bottom: 2px;">&#160;</td>
          <td valign="bottom" colspan="6" style="vertical-align: bottom; border-bottom: #000000 solid 2px;">
            <div style="text-align: center; line-height: 1.25; font-weight: bold;">As of September 30, 2024</div>
          </td>
          <td valign="bottom" nowrap="nowrap" class="cftfncell" colspan="1" style="vertical-align: bottom; padding-bottom: 2px;">&#160;</td>
        </tr>
        <tr>
          <td style="vertical-align: bottom; padding-bottom: 2px;">
            <div style="line-height: 1.25; font-family: 'Times New Roman',Times,serif;">&#160;US&#8217;000</div>
          </td>
          <td valign="bottom" class="cftguttercell" colspan="1" style="vertical-align: bottom; padding-bottom: 2px;">&#160;</td>
          <td valign="bottom" colspan="2" style="vertical-align: bottom; border-bottom: #000000 solid 2px;">
            <div style="text-align: center; line-height: 1.25; font-weight: bold;">Actual</div>
          </td>
          <td valign="bottom" nowrap="nowrap" class="cftfncell" colspan="1" style="vertical-align: bottom; padding-bottom: 2px;">&#160;</td>
          <td valign="bottom" class="cftguttercell" colspan="1" style="vertical-align: bottom; padding-bottom: 2px;">&#160;</td>
          <td valign="bottom" colspan="2" style="vertical-align: bottom; border-bottom: #000000 solid 2px;">
            <div style="text-align: center; line-height: 1.25; font-weight: bold;">As Adjusted<sup style="vertical-align: text-top; line-height: 1; font-size: smaller;">(1)</sup></div>
          </td>
          <td valign="bottom" nowrap="nowrap" class="cftfncell" colspan="1" style="vertical-align: bottom; padding-bottom: 2px;">&#160;</td>
        </tr>
        <tr>
          <td valign="bottom" style="vertical-align: top; background-color: #CCEEFF; width: 76%; padding-bottom: 2px;">
            <div style="line-height: 1.25; font-weight: bold;">Cash</div>
          </td>
          <td valign="bottom" class="cftguttercell" colspan="1" style="vertical-align: bottom; width: 1%; padding-bottom: 2px; background-color: rgb(204, 238, 255);">&#160;</td>
          <td valign="bottom" class="cftcurrcell" colspan="1" style="background-color: rgb(204, 238, 255); vertical-align: bottom; width: 1%; border-bottom: 2px solid rgb(0, 0, 0); font-weight: bold;">$ <br>
          </td>
          <td valign="bottom" class="cftnumcell" colspan="1" style="background-color: #CCEEFF; vertical-align: bottom; text-align: right; width: 9%; border-bottom: #000000 solid 2px;">
            <div style="line-height: 1.25; font-weight: bold;">2,840</div>
          </td>
          <td valign="bottom" nowrap="nowrap" class="cftfncell" colspan="1" style="background-color: #CCEEFF; vertical-align: bottom; width: 1%; padding-bottom: 2px;">&#160;</td>
          <td valign="bottom" class="cftguttercell" colspan="1" style="vertical-align: bottom; width: 1%; padding-bottom: 2px; background-color: rgb(204, 238, 255);">&#160;</td>
          <td valign="bottom" class="cftcurrcell" colspan="1" style="background-color: #CCEEFF; vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px;"><font style="font-weight: bold;">$ </font><br>
          </td>
          <td valign="bottom" class="cftnumcell" colspan="1" style="background-color: #CCEEFF; vertical-align: bottom; text-align: right; width: 9%; border-bottom: #000000 solid 2px;">
            <div style="line-height: 1.25; font-weight: bold;">10,005</div>
          </td>
          <td valign="bottom" nowrap="nowrap" class="cftfncell" colspan="1" style="background-color: #CCEEFF; vertical-align: bottom; width: 1%; padding-bottom: 2px;">&#160;</td>
        </tr>
        <tr>
          <td valign="bottom" style="vertical-align: top; width: 76%;">
            <div style="line-height: 1.25; font-weight: bold;">Debt Outstanding:</div>
          </td>
          <td valign="bottom" class="cftguttercell" colspan="1" style="vertical-align: bottom; width: 1%;">&#160;</td>
          <td valign="bottom" class="cftcurrcell" colspan="1" style="vertical-align: bottom; width: 1%;">&#160;</td>
          <td valign="bottom" class="cftnumcell" colspan="1" style="vertical-align: bottom; text-align: right; width: 9%;">&#160;</td>
          <td valign="bottom" nowrap="nowrap" class="cftfncell" colspan="1" style="vertical-align: bottom; width: 1%;">&#160;</td>
          <td valign="bottom" class="cftguttercell" colspan="1" style="vertical-align: bottom; width: 1%;">&#160;</td>
          <td valign="bottom" class="cftcurrcell" colspan="1" style="vertical-align: bottom; width: 1%;">&#160;</td>
          <td valign="bottom" class="cftnumcell" colspan="1" style="vertical-align: bottom; text-align: right; width: 9%;">&#160;</td>
          <td valign="bottom" nowrap="nowrap" class="cftfncell" colspan="1" style="vertical-align: bottom; width: 1%;">&#160;</td>
        </tr>
        <tr>
          <td valign="bottom" style="vertical-align: top; background-color: #CCEEFF; width: 76%;">
            <div style="line-height: 1.25;">Exchangeable Notes (at nominal amount)&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;</div>
          </td>
          <td valign="bottom" class="cftguttercell" colspan="1" style="vertical-align: bottom; width: 1%; background-color: rgb(204, 238, 255);">&#160;</td>
          <td valign="bottom" class="cftcurrcell" colspan="1" style="background-color: #CCEEFF; vertical-align: bottom; width: 1%;">
            <div style="line-height: 1.25;">$</div>
          </td>
          <td valign="bottom" class="cftnumcell" colspan="1" style="background-color: #CCEEFF; vertical-align: bottom; text-align: right; width: 9%;">
            <div style="line-height: 1.25;">210</div>
          </td>
          <td valign="bottom" nowrap="nowrap" class="cftfncell" colspan="1" style="background-color: #CCEEFF; vertical-align: bottom; width: 1%;">&#160;</td>
          <td valign="bottom" class="cftguttercell" colspan="1" style="vertical-align: bottom; width: 1%; background-color: rgb(204, 238, 255);">&#160;</td>
          <td valign="bottom" class="cftcurrcell" colspan="1" style="background-color: #CCEEFF; vertical-align: bottom; width: 1%;">
            <div style="line-height: 1.25;">$</div>
          </td>
          <td valign="bottom" class="cftnumcell" colspan="1" style="background-color: #CCEEFF; vertical-align: bottom; text-align: right; width: 9%;">
            <div style="line-height: 1.25;">210</div>
          </td>
          <td valign="bottom" nowrap="nowrap" class="cftfncell" colspan="1" style="background-color: #CCEEFF; vertical-align: bottom; width: 1%;">&#160;</td>
        </tr>
        <tr>
          <td valign="bottom" style="vertical-align: top; width: 76%;">
            <div style="line-height: 1.25;">Term Loan&#160;(at nominal amount)&#160; &#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;</div>
          </td>
          <td valign="bottom" class="cftguttercell" colspan="1" style="vertical-align: bottom; width: 1%;">&#160;</td>
          <td valign="bottom" class="cftcurrcell" colspan="1" style="vertical-align: bottom; width: 1%;">$<br>
          </td>
          <td valign="bottom" class="cftnumcell" colspan="1" style="vertical-align: bottom; text-align: right; width: 9%;">
            <div style="line-height: 1.25;">70,200</div>
          </td>
          <td valign="bottom" nowrap="nowrap" class="cftfncell" colspan="1" style="vertical-align: bottom; width: 1%;">&#160;</td>
          <td valign="bottom" class="cftguttercell" colspan="1" style="vertical-align: bottom; width: 1%;">&#160;</td>
          <td valign="bottom" class="cftcurrcell" colspan="1" style="vertical-align: bottom; width: 1%;">
            <div style="line-height: 1.25;">$</div>
          </td>
          <td valign="bottom" class="cftnumcell" colspan="1" style="vertical-align: bottom; text-align: right; width: 9%;">
            <div style="line-height: 1.25;">82,038</div>
          </td>
          <td valign="bottom" nowrap="nowrap" class="cftfncell" colspan="1" style="vertical-align: bottom; width: 1%;">&#160;</td>
        </tr>
        <tr>
          <td valign="bottom" style="vertical-align: top; background-color: #CCEEFF; width: 76%;">
            <div style="line-height: 1.25;">Convertible Note&#160;(at nominal amount)&#160; &#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;</div>
          </td>
          <td valign="bottom" class="cftguttercell" colspan="1" style="vertical-align: bottom; width: 1%; background-color: rgb(204, 238, 255);">&#160;</td>
          <td valign="bottom" class="cftcurrcell" colspan="1" style="background-color: #CCEEFF; vertical-align: bottom; width: 1%;">$<br>
          </td>
          <td valign="bottom" class="cftnumcell" colspan="1" style="background-color: #CCEEFF; vertical-align: bottom; text-align: right; width: 9%;">
            <div style="line-height: 1.25;">20,000</div>
          </td>
          <td valign="bottom" nowrap="nowrap" class="cftfncell" colspan="1" style="background-color: #CCEEFF; vertical-align: bottom; width: 1%;">&#160;</td>
          <td valign="bottom" class="cftguttercell" colspan="1" style="vertical-align: bottom; width: 1%; background-color: rgb(204, 238, 255);">&#160;</td>
          <td valign="bottom" class="cftcurrcell" colspan="1" style="background-color: #CCEEFF; vertical-align: bottom; width: 1%;">
            <div style="line-height: 1.25;">$</div>
          </td>
          <td valign="bottom" class="cftnumcell" colspan="1" style="background-color: #CCEEFF; vertical-align: bottom; text-align: right; width: 9%;">
            <div style="line-height: 1.25;">20,000</div>
          </td>
          <td valign="bottom" nowrap="nowrap" class="cftfncell" colspan="1" style="background-color: #CCEEFF; vertical-align: bottom; width: 1%;">&#160;</td>
        </tr>
        <tr>
          <td valign="bottom" style="vertical-align: top; width: 76%;">
            <div style="line-height: 1.25;">&#160;</div>
          </td>
          <td valign="bottom" class="cftguttercell" colspan="1" style="vertical-align: bottom; width: 1%;">&#160;</td>
          <td valign="bottom" class="cftcurrcell" colspan="1" style="vertical-align: bottom; width: 1%;">&#160;</td>
          <td valign="bottom" class="cftnumcell" colspan="1" style="vertical-align: bottom; text-align: right; width: 9%;">&#160;</td>
          <td valign="bottom" nowrap="nowrap" class="cftfncell" colspan="1" style="vertical-align: bottom; width: 1%;">&#160;</td>
          <td valign="bottom" class="cftguttercell" colspan="1" style="vertical-align: bottom; width: 1%;">&#160;</td>
          <td valign="bottom" class="cftcurrcell" colspan="1" style="vertical-align: bottom; width: 1%;">&#160;</td>
          <td valign="bottom" class="cftnumcell" colspan="1" style="vertical-align: bottom; text-align: right; width: 9%;">&#160;</td>
          <td valign="bottom" nowrap="nowrap" class="cftfncell" colspan="1" style="vertical-align: bottom; width: 1%;">&#160;</td>
        </tr>
        <tr>
          <td valign="bottom" style="vertical-align: top; background-color: #CCEEFF; width: 76%;">
            <div style="line-height: 1.25; font-weight: bold;">Equity:</div>
          </td>
          <td valign="bottom" class="cftguttercell" colspan="1" style="vertical-align: bottom; width: 1%; background-color: rgb(204, 238, 255);">&#160;</td>
          <td valign="bottom" class="cftcurrcell" colspan="1" style="background-color: #CCEEFF; vertical-align: bottom; width: 1%;">&#160;</td>
          <td valign="bottom" class="cftnumcell" colspan="1" style="background-color: #CCEEFF; vertical-align: bottom; text-align: right; width: 9%;">&#160;</td>
          <td valign="bottom" nowrap="nowrap" class="cftfncell" colspan="1" style="background-color: #CCEEFF; vertical-align: bottom; width: 1%;">&#160;</td>
          <td valign="bottom" class="cftguttercell" colspan="1" style="vertical-align: bottom; width: 1%; background-color: rgb(204, 238, 255);">&#160;</td>
          <td valign="bottom" class="cftcurrcell" colspan="1" style="background-color: #CCEEFF; vertical-align: bottom; width: 1%;">&#160;</td>
          <td valign="bottom" class="cftnumcell" colspan="1" style="background-color: #CCEEFF; vertical-align: bottom; text-align: right; width: 9%;">&#160;</td>
          <td valign="bottom" nowrap="nowrap" class="cftfncell" colspan="1" style="background-color: #CCEEFF; vertical-align: bottom; width: 1%;">&#160;</td>
        </tr>
        <tr>
          <td valign="bottom" style="vertical-align: top; width: 76%;">
            <div style="line-height: 1.25;">
              <div style="line-height: 1.25; color: #000000; font-family: 'Times New Roman', serif;">A Ordinary Shares, par value $0.0109 per share</div>
            </div>
          </td>
          <td valign="bottom" class="cftguttercell" colspan="1" style="vertical-align: bottom; width: 1%;">&#160;</td>
          <td valign="bottom" class="cftcurrcell" colspan="1" style="vertical-align: bottom; width: 1%;">
            <div style="line-height: 1.25;">$</div>
          </td>
          <td valign="bottom" class="cftnumcell" colspan="1" style="vertical-align: bottom; text-align: right; width: 9%;">
            <div style="line-height: 1.25;">2,377</div>
          </td>
          <td valign="bottom" nowrap="nowrap" class="cftfncell" colspan="1" style="vertical-align: bottom; width: 1%;">&#160;</td>
          <td valign="bottom" class="cftguttercell" colspan="1" style="vertical-align: bottom; width: 1%;">&#160;</td>
          <td valign="bottom" class="cftcurrcell" colspan="1" style="vertical-align: bottom; width: 1%;">
            <div style="line-height: 1.25;">$</div>
          </td>
          <td valign="bottom" class="cftnumcell" colspan="1" style="vertical-align: bottom; text-align: right; width: 9%;">
            <div style="line-height: 1.25;">3,573</div>
          </td>
          <td valign="bottom" nowrap="nowrap" class="cftfncell" colspan="1" style="vertical-align: bottom; width: 1%;">&#160;</td>
        </tr>
        <tr>
          <td valign="bottom" style="vertical-align: top; background-color: #CCEEFF; width: 76%;">
            <div style="line-height: 1.25;">Share Premium&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;</div>
          </td>
          <td valign="bottom" class="cftguttercell" colspan="1" style="vertical-align: bottom; width: 1%; background-color: rgb(204, 238, 255);">&#160;</td>
          <td valign="bottom" class="cftcurrcell" colspan="1" style="background-color: #CCEEFF; vertical-align: bottom; width: 1%;">
            <div style="line-height: 1.25;">$</div>
          </td>
          <td valign="bottom" class="cftnumcell" colspan="1" style="background-color: #CCEEFF; vertical-align: bottom; text-align: right; width: 9%;">
            <div style="line-height: 1.25;">57,519</div>
          </td>
          <td valign="bottom" nowrap="nowrap" class="cftfncell" colspan="1" style="background-color: #CCEEFF; vertical-align: bottom; width: 1%;">&#160;</td>
          <td valign="bottom" class="cftguttercell" colspan="1" style="vertical-align: bottom; width: 1%; background-color: rgb(204, 238, 255);">&#160;</td>
          <td valign="bottom" class="cftcurrcell" colspan="1" style="background-color: #CCEEFF; vertical-align: bottom; width: 1%;">
            <div style="line-height: 1.25;">$</div>
          </td>
          <td valign="bottom" class="cftnumcell" colspan="1" style="background-color: #CCEEFF; vertical-align: bottom; text-align: right; width: 9%;">
            <div style="line-height: 1.25;">64,640</div>
          </td>
          <td valign="bottom" nowrap="nowrap" class="cftfncell" colspan="1" style="background-color: #CCEEFF; vertical-align: bottom; width: 1%;">&#160;</td>
        </tr>
        <tr>
          <td valign="bottom" style="vertical-align: top; width: 76%;">
            <div style="line-height: 1.25;">Treasury shares&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;</div>
          </td>
          <td valign="bottom" class="cftguttercell" colspan="1" style="vertical-align: bottom; width: 1%;">&#160;</td>
          <td valign="bottom" class="cftcurrcell" colspan="1" style="vertical-align: bottom; width: 1%;">
            <div style="line-height: 1.25;">$</div>
          </td>
          <td valign="bottom" class="cftnumcell" colspan="1" style="vertical-align: bottom; text-align: right; width: 9%;">
            <div style="line-height: 1.25;">(24,922</div>
          </td>
          <td valign="bottom" nowrap="nowrap" class="cftfncell" colspan="1" style="vertical-align: bottom; width: 1%;">
            <div style="line-height: 1.25;">)</div>
          </td>
          <td valign="bottom" class="cftguttercell" colspan="1" style="vertical-align: bottom; width: 1%;">&#160;</td>
          <td valign="bottom" class="cftcurrcell" colspan="1" style="vertical-align: bottom; width: 1%;">
            <div style="line-height: 1.25;">$</div>
          </td>
          <td valign="bottom" class="cftnumcell" colspan="1" style="vertical-align: bottom; text-align: right; width: 9%;">
            <div style="line-height: 1.25;">(24,922</div>
          </td>
          <td valign="bottom" nowrap="nowrap" class="cftfncell" colspan="1" style="vertical-align: bottom; width: 1%;">
            <div style="line-height: 1.25;">)</div>
          </td>
        </tr>
        <tr>
          <td valign="bottom" style="vertical-align: top; background-color: #CCEEFF; width: 76%;">
            <div style="line-height: 1.25;">Reserves&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;</div>
          </td>
          <td valign="bottom" class="cftguttercell" colspan="1" style="vertical-align: bottom; width: 1%; background-color: rgb(204, 238, 255);">&#160;</td>
          <td valign="bottom" class="cftcurrcell" colspan="1" style="background-color: #CCEEFF; vertical-align: bottom; width: 1%;">
            <div style="line-height: 1.25;">$</div>
          </td>
          <td valign="bottom" class="cftnumcell" colspan="1" style="background-color: #CCEEFF; vertical-align: bottom; text-align: right; width: 9%;">
            <div style="line-height: 1.25;">984</div>
          </td>
          <td valign="bottom" nowrap="nowrap" class="cftfncell" colspan="1" style="background-color: #CCEEFF; vertical-align: bottom; width: 1%;">&#160;</td>
          <td valign="bottom" class="cftguttercell" colspan="1" style="vertical-align: bottom; width: 1%; background-color: rgb(204, 238, 255);">&#160;</td>
          <td valign="bottom" class="cftcurrcell" colspan="1" style="background-color: #CCEEFF; vertical-align: bottom; width: 1%;">
            <div style="line-height: 1.25;">$</div>
          </td>
          <td valign="bottom" class="cftnumcell" colspan="1" style="background-color: #CCEEFF; vertical-align: bottom; text-align: right; width: 9%;">
            <div style="line-height: 1.25;">984</div>
          </td>
          <td valign="bottom" nowrap="nowrap" class="cftfncell" colspan="1" style="background-color: #CCEEFF; vertical-align: bottom; width: 1%;">&#160;</td>
        </tr>
        <tr>
          <td valign="bottom" style="vertical-align: top; width: 76%; padding-bottom: 2px;">
            <div style="line-height: 1.25;">Accumulated deficit&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;</div>
          </td>
          <td valign="bottom" class="cftguttercell" colspan="1" style="vertical-align: bottom; width: 1%; padding-bottom: 2px;">&#160;</td>
          <td valign="bottom" class="cftcurrcell" colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: 2px solid rgb(0, 0, 0);">
            <div style="line-height: 1.25;">$</div>
          </td>
          <td valign="bottom" class="cftnumcell" colspan="1" style="vertical-align: bottom; text-align: right; width: 9%; border-bottom: 2px solid rgb(0, 0, 0);">
            <div style="line-height: 1.25;">(62,300</div>
          </td>
          <td valign="bottom" nowrap="nowrap" class="cftfncell" colspan="1" style="vertical-align: bottom; width: 1%; padding-bottom: 2px;">
            <div style="line-height: 1.25;">)</div>
          </td>
          <td valign="bottom" class="cftguttercell" colspan="1" style="vertical-align: bottom; width: 1%; padding-bottom: 2px;">&#160;</td>
          <td valign="bottom" class="cftcurrcell" colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: 2px solid rgb(0, 0, 0);">
            <div style="line-height: 1.25;">$</div>
          </td>
          <td valign="bottom" class="cftnumcell" colspan="1" style="vertical-align: bottom; text-align: right; width: 9%; border-bottom: 2px solid rgb(0, 0, 0);">
            <div style="line-height: 1.25;">(63,425</div>
          </td>
          <td valign="bottom" nowrap="nowrap" class="cftfncell" colspan="1" style="vertical-align: bottom; width: 1%; padding-bottom: 2px;">
            <div style="line-height: 1.25;">)</div>
          </td>
        </tr>
        <tr>
          <td valign="bottom" style="vertical-align: top; background-color: #CCEEFF; width: 76%; padding-bottom: 4px;">
            <div style="line-height: 1.25;">Total shareholders&#8217; equity&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;</div>
          </td>
          <td valign="bottom" class="cftguttercell" colspan="1" style="vertical-align: bottom; width: 1%; padding-bottom: 4px; background-color: rgb(204, 238, 255);">&#160;</td>
          <td valign="bottom" class="cftcurrcell" colspan="1" style="background-color: #CCEEFF; vertical-align: bottom; width: 1%; border-bottom: #000000 double 4px;">
            <div style="line-height: 1.25; font-weight: bold;">$</div>
          </td>
          <td valign="bottom" class="cftnumcell" colspan="1" style="background-color: #CCEEFF; vertical-align: bottom; text-align: right; width: 9%; border-bottom: #000000 double 4px;">
            <div style="line-height: 1.25; font-weight: bold;">(19,624</div>
          </td>
          <td valign="bottom" nowrap="nowrap" class="cftfncell" colspan="1" style="background-color: #CCEEFF; vertical-align: bottom; width: 1%; padding-bottom: 4px;">
            <div style="line-height: 1.25; font-weight: bold;">)</div>
          </td>
          <td valign="bottom" class="cftguttercell" colspan="1" style="vertical-align: bottom; width: 1%; padding-bottom: 4px; background-color: rgb(204, 238, 255);">&#160;</td>
          <td valign="bottom" class="cftcurrcell" colspan="1" style="background-color: #CCEEFF; vertical-align: bottom; width: 1%; border-bottom: #000000 double 4px;">
            <div style="line-height: 1.25; font-weight: bold;">$</div>
          </td>
          <td valign="bottom" class="cftnumcell" colspan="1" style="background-color: #CCEEFF; vertical-align: bottom; text-align: right; width: 9%; border-bottom: #000000 double 4px;">
            <div style="line-height: 1.25; font-weight: bold;">(19,150</div>
          </td>
          <td valign="bottom" nowrap="nowrap" class="cftfncell" colspan="1" style="background-color: #CCEEFF; vertical-align: bottom; width: 1%; padding-bottom: 4px;">
            <div style="line-height: 1.25; font-weight: bold;">)</div>
          </td>
        </tr>
        <tr>
          <td valign="bottom" style="vertical-align: top; width: 76%; padding-bottom: 4px;">
            <div style="text-indent: 36pt; line-height: 1.25;">Total Capitalization&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;</div>
          </td>
          <td valign="bottom" class="cftguttercell" colspan="1" style="vertical-align: bottom; width: 1%; padding-bottom: 4px;">&#160;</td>
          <td valign="bottom" class="cftcurrcell" colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: 4px double rgb(0, 0, 0);">
            <div style="line-height: 1.25; font-weight: bold;">$</div>
          </td>
          <td valign="bottom" class="cftnumcell" colspan="1" style="vertical-align: bottom; text-align: right; width: 9%; border-bottom: 4px double rgb(0, 0, 0);">
            <div style="line-height: 1.25; font-weight: bold;">64,068</div>
          </td>
          <td valign="bottom" nowrap="nowrap" class="cftfncell" colspan="1" style="vertical-align: bottom; width: 1%; padding-bottom: 4px;">&#160;</td>
          <td valign="bottom" class="cftguttercell" colspan="1" style="vertical-align: bottom; width: 1%; padding-bottom: 4px;">&#160;</td>
          <td valign="bottom" class="cftcurrcell" colspan="1" style="vertical-align: bottom; width: 1%; border-bottom: 4px double rgb(0, 0, 0);">
            <div style="line-height: 1.25; font-weight: bold;">$</div>
          </td>
          <td valign="bottom" class="cftnumcell" colspan="1" style="vertical-align: bottom; text-align: right; width: 9%; border-bottom: 4px double rgb(0, 0, 0);">
            <div style="line-height: 1.25; font-weight: bold;">83,099</div>
          </td>
          <td valign="bottom" nowrap="nowrap" class="cftfncell" colspan="1" style="vertical-align: bottom; width: 1%; padding-bottom: 4px;">&#160;</td>
        </tr>

    </table>
    <div style="line-height: 1.25;"><br style="line-height: 1.25;">
    </div>
    <table cellspacing="0" cellpadding="0" style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;" class="DSPFListTable" id="z696f580b8bfb402da791118268701144">

        <tr>
          <td style="width: 20.25pt;"><br>
          </td>
          <td style="width: 27pt; vertical-align: top;">(1)</td>
          <td style="width: auto; vertical-align: top; text-align: justify;">
            <div>
              <div style="line-height: 1.25; color: rgb(0, 0, 0); font-family: 'Times New Roman',serif;">The number of A Ordinary Shares issued and outstanding excludes: 48,506,672&#160; A Ordinary Shares issuable upon exercise of outstanding stock options at
                exercise prices that range from US$0.12-US$1.29 per share; 51,200,000 A Ordinary Shares represented by ADSs issuable upon the exercise of outstanding warrants; 24,691,358 A Ordinary Shares represented by ADSs issuable upon conversion of the
                MiCo Convertible Note.</div>
            </div>
          </td>
        </tr>

    </table>
    <div style="line-height: 1.25;"><br style="line-height: 1.25;">
    </div>
    <div style="clear: both; margin-top: 10pt; margin-bottom: 10pt;" class="BRPFPageBreakArea">
      <div class="BRPFPageNumberArea" style="text-align: center;"><font class="BRPFPageNumber" style="font-weight: normal; font-style: normal;">10</font></div>
      <div style="page-break-after: always;" class="BRPFPageBreak">
        <hr noshade="noshade" style="margin: 4px 0px; width: 100%; border-width: 0; height: 2px; color: #000000; background-color: #000000; clear: both;"></div>
    </div>
    <div style="text-align: center; line-height: 1.25; font-weight: bold;">SELLING <a name="SHAREHOLDER"><!--Anchor--></a>SHAREHOLDER</div>
    <div style="line-height: 1.25;">&#160;</div>
    <div style="text-align: justify; text-indent: 36pt; line-height: 1.25;">
      <div style="text-indent: 36pt; line-height: 1.25; color: #000000; font-family: 'Times New Roman', serif;">We are registering the resale of 4.29 million ADSs (representing 85.8 million A Ordinary Shares), including 2.5 million ADSs issuable upon the
        exercise of the Warrants pursuant to the registration rights provisions of the Warrants.&#160; Perceptive is an investment manager with an expertise in healthcare. The term &#8220;selling shareholder&#8221; includes the entities identified in the table below (as
        such table may be amended from time to time by means of an amendment to the registration statement of which this prospectus forms a part or by a supplement to this prospectus) and any permitted assignees of the Warrants from Perceptive. Except as
        described herein or in the documents incorporated by reference herein, we did not have any material relationship with Perceptive prior to our credit agreement with Perceptive.</div>
    </div>
    <div style="line-height: 1.25;">&#160;</div>
    <div style="text-align: justify; text-indent: 36pt; line-height: 1.25;">Our registration of the resale of the securities covered by this prospectus does not necessarily mean that the selling shareholder will sell any or all of the securities.</div>
    <div style="line-height: 1.25;">&#160;</div>
    <div style="text-align: justify; text-indent: 36pt; line-height: 1.25;">The information in the table below is based upon information provided by the selling shareholder.</div>
    <div style="line-height: 1.25;">&#160;</div>
    <table cellspacing="0" cellpadding="0" border="0" style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000;" id="za3ef41f8aa67453db8b0a5889e7fe197">

        <tr>
          <td style="width: 37%; vertical-align: bottom; border-bottom: 2px solid rgb(0, 0, 0);">
            <div style="text-align: center; line-height: 1.25;">Selling Shareholder</div>
          </td>
          <td style="width: 1.01%; vertical-align: bottom;">
            <div style="line-height: 1.25;">&#160;</div>
          </td>
          <td colspan="2" style="vertical-align: bottom; border-bottom: 2px solid rgb(0, 0, 0);">
            <div style="text-align: center; line-height: 1.25;">Ordinary Shares Beneficially<br>
              Owned Prior to Offering/<br>
              Percentage of Class</div>
          </td>
          <td style="width: 1%; vertical-align: bottom;">
            <div style="line-height: 1.25;">&#160;</div>
          </td>
          <td style="width: 1%; vertical-align: bottom;">
            <div style="line-height: 1.25;">&#160;</div>
          </td>
          <td colspan="2" style="vertical-align: bottom; border-bottom: 2px solid rgb(0, 0, 0);">
            <div style="text-align: center; line-height: 1.25;">Ordinary Shares</div>
            <div style="text-align: center; line-height: 1.25;">Being Offered</div>
          </td>
          <td style="width: 1%; vertical-align: bottom;">
            <div style="line-height: 1.25;">&#160;</div>
          </td>
          <td style="width: 1%; vertical-align: bottom;">
            <div style="line-height: 1.25;">&#160;</div>
          </td>
          <td style="width: 9%; vertical-align: bottom; border-bottom: 2px solid rgb(0, 0, 0);">
            <div style="text-align: center; line-height: 1.25;">Ordinary Shares Beneficially Owned Upon Completion of Offering /<br>
              Percentage of Class</div>
          </td>
          <td colspan="1" style="width: 1%; vertical-align: bottom; border-bottom: 2px solid rgb(0, 0, 0);">&#160;</td>
        </tr>
        <tr>
          <td style="width: 37%; vertical-align: top; background-color: rgb(204, 238, 255);">
            <div style="text-align: center; line-height: 1.25;">Perceptive<sup style="vertical-align: text-top; line-height: 1; font-size: smaller;">(1)</sup></div>
          </td>
          <td style="width: 1.01%; vertical-align: top; background-color: #CCEEFF;">
            <div style="line-height: 1.25;">&#160;</div>
          </td>
          <td style="width: 1%; vertical-align: top; background-color: #CCEEFF;">
            <div style="line-height: 1.25;">&#160;</div>
          </td>
          <td style="width: 9%; vertical-align: top; background-color: rgb(204, 238, 255);">
            <div style="text-align: center; line-height: 1.25;">18.3%<sup style="vertical-align: text-top; line-height: 1; font-size: smaller;"> (2)</sup>&#160;</div>
            <div style="line-height: 1.25;">&#160;</div>
          </td>
          <td style="width: 1%; vertical-align: top; background-color: #CCEEFF;">
            <div style="line-height: 1.25;">&#160;</div>
          </td>
          <td style="width: 1%; vertical-align: top; background-color: #CCEEFF;">
            <div style="line-height: 1.25;">&#160;</div>
          </td>
          <td style="width: 1%; vertical-align: top; background-color: #CCEEFF;">
            <div style="line-height: 1.25;">&#160;</div>
          </td>
          <td style="width: 37%; vertical-align: top; background-color: rgb(204, 238, 255);">
            <div style="text-align: center; line-height: 1.25;">
              <div style="line-height: 1.25; color: rgb(0, 0, 0); font-family: 'Times New Roman',serif;">85.8 million A Ordinary Shares (represented by 4.29 million ADSs)<sup style="vertical-align: text-top; line-height: 1; font-size: smaller;"> (3)</sup></div>
            </div>
          </td>
          <td style="width: 1%; vertical-align: top; background-color: #CCEEFF;">
            <div style="line-height: 1.25;">&#160;</div>
          </td>
          <td style="width: 1%; vertical-align: top; background-color: #CCEEFF;">
            <div style="line-height: 1.25;">&#160;</div>
          </td>
          <td style="width: 9%; vertical-align: top; background-color: rgb(204, 238, 255);">
            <div style="text-align: center; line-height: 1.25;">-- %<sup style="vertical-align: text-top; line-height: 1; font-size: smaller;">(4)</sup></div>
            <div style="line-height: 1.25;">&#160;</div>
          </td>
          <td colspan="1" style="width: 1%; vertical-align: top; background-color: rgb(204, 238, 255);">&#160;</td>
        </tr>

    </table>
    <div style="line-height: 1.25;">
      <div style="text-align: justify; text-indent: -27pt; margin-left: 27pt; line-height: 1.25; color: #000000; font-family: 'Times New Roman', serif;"><br>
      </div>
    </div>
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        <tr>
          <td style="width: 27pt; vertical-align: top;">(1)</td>
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            <div>Each of Perceptive Credit Holdings II, LP and Perceptive Credit Holdings III, LP is a Delaware limited partnership and their address is 51 Astor Place, 10<sup style="vertical-align: text-top; line-height: 1; font-size: smaller;">th</sup>
              Floor, New York, New York 10003.</div>
          </td>
        </tr>

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                <div style="line-height: 1.25; color: rgb(0, 0, 0); font-family: 'Times New Roman',serif;">
                  <div style="line-height: 1.25; color: rgb(0, 0, 0);">Represents 85.8 million A Ordinary Shares, including (a) 35.8 million A Ordinary Shares represented by 1.79 million ADSs of the selling shareholder and (b) 50 million A Ordinary Shares
                    represented by 2.5 million ADSs that may be acquired upon full exercise of the Warrants of the selling shareholder, although the exercise of the Warrants is subject to a 9.99% beneficial ownership cap.</div>
                </div>
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        <tr>
          <td style="width: 27pt; vertical-align: top;">(3)</td>
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            <div>Assuming full exercise of the Warrants.</div>
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        <tr>
          <td style="width: 27pt; vertical-align: top;">(4)</td>
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            <div>
              <div style="text-align: left; line-height: 1.25; color: #000000; font-family: 'Times New Roman', serif;">Assuming all ADSs representing A Ordinary Shares being registered for resale hereunder are sold.</div>
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    <div style="line-height: 1.25;"><br style="line-height: 1.25;">
    </div>
    <div style="clear: both; margin-top: 10pt; margin-bottom: 10pt;" class="BRPFPageBreakArea">
      <div class="BRPFPageNumberArea" style="text-align: center;"><font class="BRPFPageNumber" style="font-weight: normal; font-style: normal;">11</font></div>
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    <div style="text-align: center; line-height: 1.25; font-weight: bold;"><a name="PLAN"><!--Anchor--></a>PLAN OF DISTRIBUTION</div>
    <div style="line-height: 1.25;">&#160;</div>
    <div style="text-align: justify; text-indent: 36pt; line-height: 1.25;">The selling shareholder, may, from time to time, sell, transfer or otherwise dispose of any or all of its ADSs or interests therein on any stock exchange, market or trading
      facility on which the ADSs are traded or in private transactions. These dispositions may be at fixed prices, at prevailing market prices at the time of sale, at prices related to the prevailing market price, at varying prices determined at the time
      of sale, or at negotiated prices.</div>
    <div style="line-height: 1.25;">&#160;</div>
    <div style="text-indent: 36pt; line-height: 1.25;">The selling shareholder may use any one or more of the following methods when disposing of shares or interests therein:</div>
    <div style="line-height: 1.25;">&#160;</div>
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        <tr>
          <td style="width: 20.25pt;"><br>
          </td>
          <td style="width: 27pt; vertical-align: top;">&#8226;</td>
          <td style="width: auto; vertical-align: top; text-align: justify;">
            <div>ordinary brokerage transactions and transactions in which the broker-dealer solicits purchasers;</div>
          </td>
        </tr>

    </table>
    <div style="line-height: 1.25;">&#160;</div>
    <table cellspacing="0" cellpadding="0" style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;" class="DSPFListTable" id="z3dc65e678f63459ba7055357f1abef1f">

        <tr>
          <td style="width: 20.25pt;"><br>
          </td>
          <td style="width: 27pt; vertical-align: top;">&#8226;</td>
          <td style="width: auto; vertical-align: top; text-align: justify;">
            <div>block trades in which the broker-dealer will attempt to sell the shares as agent, but may position and resell a portion of the block as principal to facilitate the transaction;</div>
          </td>
        </tr>

    </table>
    <div style="line-height: 1.25;">&#160;</div>
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        <tr>
          <td style="width: 20.25pt;"><br>
          </td>
          <td style="width: 27pt; vertical-align: top;">&#8226;</td>
          <td style="width: auto; vertical-align: top; text-align: justify;">
            <div>purchases by a broker-dealer as principal and resale by the broker-dealer for its own account;</div>
          </td>
        </tr>

    </table>
    <div style="line-height: 1.25;">&#160;</div>
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        <tr>
          <td style="width: 20.25pt;"><br>
          </td>
          <td style="width: 27pt; vertical-align: top;">&#8226;</td>
          <td style="width: auto; vertical-align: top; text-align: justify;">
            <div>an exchange distribution in accordance with the rules of the applicable exchange;</div>
          </td>
        </tr>

    </table>
    <div style="line-height: 1.25;">&#160;</div>
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        <tr>
          <td style="width: 20.25pt;"><br>
          </td>
          <td style="width: 27pt; vertical-align: top;">&#8226;</td>
          <td style="width: auto; vertical-align: top; text-align: justify;">
            <div>privately negotiated transactions;</div>
          </td>
        </tr>

    </table>
    <div style="line-height: 1.25;">&#160;</div>
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        <tr>
          <td style="width: 20.25pt;"><br>
          </td>
          <td style="width: 27pt; vertical-align: top;">&#8226;</td>
          <td style="width: auto; vertical-align: top; text-align: justify;">
            <div>short sales effected after the date the registration statement of which this prospectus is a part is declared effective by the Commission;</div>
          </td>
        </tr>

    </table>
    <div style="line-height: 1.25;">&#160;</div>
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        <tr>
          <td style="width: 20.25pt;"><br>
          </td>
          <td style="width: 27pt; vertical-align: top;">&#8226;</td>
          <td style="width: auto; vertical-align: top; text-align: justify;">
            <div>through the writing or settlement of options or other hedging transactions, whether through an options exchange or otherwise;</div>
          </td>
        </tr>

    </table>
    <div style="line-height: 1.25;">&#160;</div>
    <table cellspacing="0" cellpadding="0" style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;" class="DSPFListTable" id="z318ae8092e3241c79ea1116a3b658b89">

        <tr>
          <td style="width: 20.25pt;"><br>
          </td>
          <td style="width: 27pt; vertical-align: top;">&#8226;</td>
          <td style="width: auto; vertical-align: top; text-align: justify;">
            <div>through agreements between broker-dealers and the selling shareholder to sell a specified number of such shares at a stipulated price per share;</div>
          </td>
        </tr>

    </table>
    <div style="line-height: 1.25;">&#160;</div>
    <table cellspacing="0" cellpadding="0" style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;" class="DSPFListTable" id="z0edebdb6d6c246f5a1d7fdf67cf67bbc">

        <tr>
          <td style="width: 20.25pt;"><br>
          </td>
          <td style="width: 27pt; vertical-align: top;">&#8226;</td>
          <td style="width: auto; vertical-align: top; text-align: justify;">
            <div>a combination of any such methods of sale; and</div>
          </td>
        </tr>

    </table>
    <div style="line-height: 1.25;">&#160;</div>
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        <tr>
          <td style="width: 20.25pt;"><br>
          </td>
          <td style="width: 27pt; vertical-align: top;">&#8226;</td>
          <td style="width: auto; vertical-align: top; text-align: justify;">
            <div>any other method permitted by applicable law.</div>
          </td>
        </tr>

    </table>
    <div style="line-height: 1.25;">&#160;</div>
    <div style="text-align: justify; text-indent: 36pt; line-height: 1.25;">In connection with the sale of our ADSs or interests therein, the selling shareholder may enter into hedging transactions with broker-dealers or other financial institutions, which
      may in turn engage in short sales of the ADSs or interests therein in the course of hedging the positions they assume. The selling shareholder may also sell ADSs or interests therein short and deliver these securities to close out their short
      positions, or loan or pledge the ADSs or interests therein to broker-dealers that in turn may sell these securities. The selling shareholder may also enter into options or other transactions with broker-dealers or other financial institutions or the
      creation of one or more derivative securities which require the delivery to each such broker-dealer or other financial institution of shares offered by this prospectus, which shares such broker-dealer or other financial institution may resell
      pursuant to this prospectus (as supplemented or amended to reflect such transaction).</div>
    <div style="line-height: 1.25;">&#160;</div>
    <div style="text-align: justify; text-indent: 36pt; line-height: 1.25;">
      <div style="text-indent: 36pt; line-height: 1.25; color: #000000; font-family: 'Times New Roman', serif;">The aggregate proceeds to the selling shareholder from the sale of the ADSs or interests therein offered by the selling shareholder will be the
        purchase price of such securities less discounts or commissions, if any. The selling shareholder reserves the right to accept and, together with its agents from time to time, to reject, in whole or in part, any proposed purchase of ADSs or
        interests therein to be made directly or through agents. We will not receive any of the proceeds from this offering.</div>
    </div>
    <div style="line-height: 1.25;">&#160;</div>
    <div style="text-align: justify; text-indent: 36pt; line-height: 1.25;">The selling shareholder also may resell all or a portion of the ADS or interests therein in open market transactions in reliance upon Rule 144 under the Securities Act of 1933,
      provided that they meet the criteria and conform to the requirements of that rule.</div>
    <div style="line-height: 1.25;">&#160;</div>
    <div style="text-align: justify; text-indent: 36pt; line-height: 1.25;">The selling shareholder and any underwriters, broker-dealers or agents that participate in the sale of the ADSs or interests therein may be &#8220;underwriters&#8221; within the meaning of
      Section 2(a)(11) of the Securities Act. Any discounts, commissions, concessions or profit they earn on any resale of the shares may be underwriting discounts and commissions under the Securities Act. If the selling shareholder is an &#8220;underwriter&#8221;
      within the meaning of Section 2(a)(11) of the Securities Act, it will be subject to the prospectus delivery requirements of the Securities Act.</div>
    <div style="line-height: 1.25;">&#160;</div>
    <div style="clear: both; margin-top: 10pt; margin-bottom: 10pt;" class="BRPFPageBreakArea">
      <div class="BRPFPageNumberArea" style="text-align: center;"><font class="BRPFPageNumber" style="font-weight: normal; font-style: normal;">12</font></div>
      <div style="page-break-after: always;" class="BRPFPageBreak">
        <hr noshade="noshade" style="margin: 4px 0px; width: 100%; border-width: 0; height: 2px; color: #000000; background-color: #000000; clear: both;"></div>
    </div>
    <div style="text-align: justify; text-indent: 36pt; line-height: 1.25;">To the extent required, the ADSs or interest therein to be sold, the name of the selling shareholder, the respective purchase prices and public offering prices, the names of any
      agents, dealer or underwriter, and any applicable commissions or discounts with respect to a particular offer will be set forth in an accompanying prospectus supplement or, if appropriate, a post-effective amendment to the registration statement that
      includes this prospectus.</div>
    <div style="line-height: 1.25;">&#160;</div>
    <div style="text-align: justify; text-indent: 36pt; line-height: 1.25;">In order to comply with the securities laws of some states, if applicable, the ADSs or interests therein may be sold in those jurisdictions only through registered or licensed
      brokers or dealers. In addition, in some states the ADSs or interests therein may not be sold unless it has been registered or qualified for sale or an exemption from registration or qualification requirements is available and is complied with.</div>
    <div style="line-height: 1.25;">&#160;</div>
    <div style="text-align: justify; text-indent: 36pt; line-height: 1.25;">We have advised the selling shareholder that the anti-manipulation rules of Regulation M under the Exchange Act may apply to sales of shares in the market and to the activities of
      the selling shareholder and its affiliates. In addition, to the extent applicable we will make copies of this prospectus (as it may be supplemented or amended from time to time) available to the selling shareholder for the purpose of satisfying the
      prospectus delivery requirements of the Securities Act. The selling shareholder may indemnify any broker-dealer that participates in transactions involving the sale of the shares against certain liabilities, including liabilities arising under the
      Securities Act.</div>
    <div style="line-height: 1.25;">&#160;</div>
    <div style="text-align: justify; text-indent: 36pt; line-height: 1.25;">We have agreed with the selling shareholder to keep the registration statement of which this prospectus constitutes a part effective until the earlier of (1) such time as all of
      the shares covered by this prospectus have been disposed of pursuant to and in accordance with the registration statement or have been withdrawn.</div>
    <div style="line-height: 1.25;">&#160;</div>
    <div style="clear: both; margin-top: 10pt; margin-bottom: 10pt;" class="BRPFPageBreakArea">
      <div class="BRPFPageNumberArea" style="text-align: center;"><font class="BRPFPageNumber" style="font-weight: normal; font-style: normal;">13</font></div>
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    <div style="text-align: center; line-height: 1.25; font-weight: bold;">DESCRIPTION OF OUR <a name="ADSs"><!--Anchor--></a>ADSs</div>
    <div style="line-height: 1.25;">&#160;</div>
    <div style="text-align: justify; text-indent: 36pt; line-height: 1.25;">
      <div style="text-indent: 36pt; line-height: 1.25; color: #000000; font-family: 'Times New Roman', serif;">The primary trading market for our ADSs is the NASDAQ Global Select Market, where our ADSs are listed and traded under the symbol &#8220;TRIB&#8221;. The
        ratio of ADSs to underlying A Ordinary Shares is 1 ADS : 20 A Ordinary Shares. The Bank of New York Mellon is the depositary for the ADSs pursuant to the deposit agreement filed with the Commission on January 15, 2004 as an exhibit to our Form F-6,
        registration no. 333-111946.</div>
      <div style="text-align: left; line-height: 1.25; color: #000000; font-family: 'Times New Roman', serif;">&#160;</div>
      <div style="text-indent: 36pt; line-height: 1.25; color: #000000; font-family: 'Times New Roman', serif;">Descriptions of our A Ordinary Shares and ADSs can be found in our Annual Report on Form 20-F&#160;for the year ended December 31, 2023, which
        descriptions are incorporated herein by reference.</div>
    </div>
    <div style="line-height: 1.25;">&#160;</div>
    <div style="text-align: center; line-height: 1.25; font-weight: bold;"><a name="TAXATION"><!--Anchor--></a>TAXATION</div>
    <div style="line-height: 1.25;">&#160;</div>
    <div style="text-indent: 36pt; line-height: 1.25;">A description of taxation affecting our ADSs can be found in our Annual Report on Form 20-F for the year ended December 31, 2023, which description is incorporated herein by reference.</div>
    <div style="line-height: 1.25;">&#160;</div>
    <div style="text-align: center; line-height: 1.25; font-weight: bold;">AUTHORIZED <a name="REPRESENTATIVE"><!--Anchor--></a>REPRESENTATIVE</div>
    <div style="line-height: 1.25;">&#160;</div>
    <div style="text-align: justify; text-indent: 36pt; line-height: 1.25;">Our authorized representative in the United States for this offering as required pursuant to Section&#160;6(a) of the Securities Act is Puglisi &amp; Associates; 850 Library Avenue,
      Suite 204; Newark, Delaware 19711. We have agreed to indemnify the authorized representative against liabilities under the Securities Act of 1933.</div>
    <div style="line-height: 1.25;">&#160;</div>
    <div style="text-align: center; line-height: 1.25; font-weight: bold;">OFFERING <a name="EXPENSES"><!--Anchor--></a>EXPENSES</div>
    <div style="line-height: 1.25;">&#160;</div>
    <div style="text-align: justify; text-indent: 36pt; line-height: 1.25;">The following is a statement of expenses in connection with the distribution of the securities registered. All amounts shown are estimates except the Commission registration fee.&#160;
      The estimates do not include expenses related to offerings of particular securities. Each prospectus supplement describing an offering of securities will reflect the estimated expenses related to the offering of securities under that prospectus
      supplement.</div>
    <div style="line-height: 1.25;">&#160;</div>
    <table cellspacing="0" cellpadding="0" border="0" align="center" class="cfttable" id="z45a42b1a55d843698e37c10396ee8e02" style="width: 60%; color: #000000; font-family: 'Times New Roman', Times, serif; font-size: 10pt; text-align: left;">

        <tr>
          <td valign="bottom" style="vertical-align: bottom; background-color: rgb(204, 238, 255); width: 85%;">
            <div style="text-indent: -7.2pt; margin-left: 7.2pt; line-height: 1.25;">Commission registration fee&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;</div>
          </td>
          <td valign="bottom" class="cftguttercell" colspan="1" style="vertical-align: bottom; width: 1%; background-color: rgb(204, 238, 255);">&#160;</td>
          <td valign="bottom" class="cftcurrcell" colspan="1" style="background-color: #CCEEFF; vertical-align: bottom; width: 1%;">
            <div style="line-height: 1.25;">$</div>
          </td>
          <td valign="bottom" class="cftnumcell" colspan="1" style="background-color: rgb(204, 238, 255); vertical-align: bottom; text-align: right; width: 12%;">
            <div style="line-height: 1.25; color: rgb(0, 0, 0); font-family: 'Times New Roman',serif;">446</div>
          </td>
          <td valign="bottom" nowrap="nowrap" class="cftfncell" colspan="1" style="background-color: #CCEEFF; vertical-align: bottom; width: 1%;">
            <div style="line-height: 1.25;"><br>
            </div>
          </td>
        </tr>
        <tr>
          <td valign="bottom" style="vertical-align: bottom; width: 85%;">
            <div style="text-indent: -7.2pt; margin-left: 7.2pt; line-height: 1.25;">EDGAR and printing fees&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;</div>
          </td>
          <td valign="bottom" class="cftguttercell" colspan="1" style="vertical-align: bottom; width: 1%;">&#160;</td>
          <td valign="bottom" class="cftcurrcell" colspan="1" style="vertical-align: bottom; width: 1%;">
            <div style="line-height: 1.25;">$</div>
          </td>
          <td valign="bottom" class="cftnumcell" colspan="1" style="vertical-align: bottom; text-align: right; width: 12%;">
            <div style="line-height: 1.25;">1,000</div>
          </td>
          <td valign="bottom" nowrap="nowrap" class="cftfncell" colspan="1" style="vertical-align: bottom; width: 1%;">&#160;</td>
        </tr>
        <tr>
          <td valign="bottom" style="vertical-align: bottom; background-color: rgb(204, 238, 255); width: 85%;">
            <div style="text-indent: -7.2pt; margin-left: 7.2pt; line-height: 1.25;">Legal fees and expenses&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;</div>
          </td>
          <td valign="bottom" class="cftguttercell" colspan="1" style="vertical-align: bottom; width: 1%; background-color: rgb(204, 238, 255);">&#160;</td>
          <td valign="bottom" class="cftcurrcell" colspan="1" style="background-color: #CCEEFF; vertical-align: bottom; width: 1%;">
            <div style="line-height: 1.25;">$</div>
          </td>
          <td valign="bottom" class="cftnumcell" colspan="1" style="background-color: rgb(204, 238, 255); vertical-align: bottom; text-align: right; width: 12%;">
            <div style="line-height: 1.25;">10,000</div>
          </td>
          <td valign="bottom" nowrap="nowrap" class="cftfncell" colspan="1" style="background-color: #CCEEFF; vertical-align: bottom; width: 1%;">&#160;</td>
        </tr>
        <tr>
          <td valign="bottom" style="vertical-align: bottom; width: 85%;">
            <div style="text-indent: -7.2pt; margin-left: 7.2pt; line-height: 1.25;">Accounting fees and expenses&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;</div>
          </td>
          <td valign="bottom" class="cftguttercell" colspan="1" style="vertical-align: bottom; width: 1%;">&#160;</td>
          <td valign="bottom" class="cftcurrcell" colspan="1" style="vertical-align: bottom; width: 1%;">
            <div style="line-height: 1.25;">$</div>
          </td>
          <td valign="bottom" class="cftnumcell" colspan="1" style="vertical-align: bottom; text-align: right; width: 12%;">
            <div style="line-height: 1.25;">5,500</div>
          </td>
          <td valign="bottom" nowrap="nowrap" class="cftfncell" colspan="1" style="vertical-align: bottom; width: 1%;">&#160;</td>
        </tr>
        <tr>
          <td valign="bottom" style="vertical-align: bottom; background-color: rgb(204, 238, 255); width: 85%; padding-bottom: 2px;">
            <div style="text-indent: -7.2pt; margin-left: 7.2pt; line-height: 1.25;">Miscellaneous&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;</div>
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          <td valign="bottom" class="cftguttercell" colspan="1" style="vertical-align: bottom; width: 1%; padding-bottom: 2px; background-color: rgb(204, 238, 255);">&#160;</td>
          <td valign="bottom" class="cftcurrcell" colspan="1" style="background-color: #CCEEFF; vertical-align: bottom; width: 1%; border-bottom: #000000 solid 2px;">
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          </td>
          <td valign="bottom" class="cftnumcell" colspan="1" style="background-color: rgb(204, 238, 255); vertical-align: bottom; text-align: right; width: 12%; border-bottom: 2px solid rgb(0, 0, 0);">
            <div style="line-height: 1.25;">2,000</div>
          </td>
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            <div style="line-height: 1.25;">Total&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;</div>
          </td>
          <td valign="bottom" class="cftguttercell" colspan="1" style="vertical-align: bottom; width: 1%; padding-bottom: 4px;">&#160;</td>
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            <div style="line-height: 1.25;"><br>
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    <div style="text-align: center; line-height: 1.25; font-weight: bold;">MATERIAL <a name="CHANGES"><!--Anchor--></a>CHANGES</div>
    <div style="line-height: 1.25;">&#160;</div>
    <div style="text-align: justify; text-indent: 36pt; line-height: 1.25;">Except as otherwise described in our Annual Report on Form 20-F for the fiscal year ended December 31, 2023, and in our Reports of Foreign Private Issuer on Form 6-K filed under
      the Exchange Act and incorporated by reference or disclosed herein, no reportable material changes have occurred since December 31, 2023.</div>
    <div style="line-height: 1.25;">&#160;</div>
    <div style="text-align: center; line-height: 1.25; font-weight: bold;">LEGAL <a name="MATTERS"><!--Anchor--></a>MATTERS</div>
    <div style="line-height: 1.25;">&#160;</div>
    <div style="text-align: justify; text-indent: 36pt; line-height: 1.25;">
      <div style="text-indent: 36pt; line-height: 1.25; color: #000000; font-family: 'Times New Roman', serif;">Carter Ledyard &amp; Milburn LLP, New York, New York, will be passing upon matters of United States law for us with respect to securities
        offered by this prospectus.&#160; The validity of the A Ordinary Shares represented by ADSs offered hereby will be passed upon for us by Matheson LLP, Dublin, Ireland.</div>
    </div>
    <div style="line-height: 1.25;">&#160;</div>
    <div style="text-align: center; line-height: 1.25; font-weight: bold;"><a name="EXPERTS"><!--Anchor--></a>EXPERTS</div>
    <div style="line-height: 1.25;">&#160;</div>
    <div style="text-align: justify; text-indent: 36pt; line-height: 1.25;">
      <div style="text-indent: 36pt; line-height: 1.25; color: #000000; font-family: 'Times New Roman', serif;">
        <div style="text-indent: 36pt; line-height: 1.25; color: #000000;">
          <div style="text-indent: 36pt; margin-right: 0.1pt; margin-left: 0.1pt; line-height: 1.25; font-family: 'Times New Roman', Times, serif;">The audited consolidated financial statements of Trinity Biotech Plc incorporated by reference in this
            prospectus and elsewhere in the registration statement have been so incorporated by reference in reliance on the report of Grant Thornton, an independent registered public accounting firm, upon the authority of said firm as experts in auditing
            and accounting.</div>
        </div>
      </div>
      <div style="text-indent: 36pt; line-height: 1.25; color: #000000; font-family: 'Times New Roman', serif;"> <br>
      </div>
      <div style="text-indent: 36pt; line-height: 1.25; color: #000000; font-family: 'Times New Roman', serif;">
        <div style="text-indent: 36pt; line-height: 1.25; color: #000000;">
          <div style="text-indent: 36pt; line-height: 1.25; color: #000000;">
            <div style="text-indent: 36pt; line-height: 1.25; font-family: 'Times New Roman', Times, serif;">The audited Statement of Assets Acquired and Liabilities Assumed with respect to the asset acquisition of Waveform Technologies, Inc. incorporated
              by reference in this prospectus and elsewhere in the registration statement have been so incorporated by reference in reliance on the report of Grant Thornton, as independent auditors, upon the authority of said firm as experts in auditing
              and accounting.</div>
          </div>
        </div>
      </div>
    </div>
    <div style="text-align: justify; text-indent: 36pt; line-height: 1.25;"> <br>
    </div>
    <div style="clear: both; margin-top: 10pt; margin-bottom: 10pt;" class="BRPFPageBreakArea">
      <div class="BRPFPageNumberArea" style="text-align: center;"><font class="BRPFPageNumber" style="font-weight: normal; font-style: normal;">14</font></div>
      <div style="page-break-after: always;" class="BRPFPageBreak">
        <hr noshade="noshade" style="margin: 4px 0px; width: 100%; border-width: 0; height: 2px; color: #000000; background-color: #000000; clear: both;"></div>
    </div>
    <div style="text-align: center; line-height: 1.25; font-weight: bold;">WHERE YOU CAN FIND MORE <a name="INFORMATION"><!--Anchor--></a>INFORMATION</div>
    <div style="line-height: 1.25;">&#160;</div>
    <div style="text-align: justify; text-indent: 36pt; line-height: 1.25;">This prospectus is a part of a registration statement on Form F-3 that we filed with the Commission under the Securities Act.&#160; We refer you to this registration statement for
      further information about us and the securities offered hereby.</div>
    <div style="line-height: 1.25;">&#160;</div>
    <div style="text-align: justify; text-indent: 36pt; line-height: 1.25;">&#160;We file annual and special reports and other information with the Commission (Commission File Number 000-22320). These filings contain important information that does not appear
      in this prospectus. Our SEC filings are also available on the Commission Internet site at www.sec.gov, which contains periodic reports and other information regarding issuers that file electronically.</div>
    <div style="line-height: 1.25;">&#160;</div>
    <div style="text-align: center; line-height: 1.25; font-weight: bold;">INCORPORATION OF CERTAIN INFORMATION BY <a name="REFERENCE"><!--Anchor--></a>REFERENCE</div>
    <div style="line-height: 1.25;">&#160;</div>
    <div style="text-align: justify; text-indent: 36pt; line-height: 1.25;">We file annual and special reports and other information with the Commission (File Number 000-22320).&#160; These filings contain important information which does not appear in this
      prospectus. The Commission allows us to &#8220;incorporate by reference&#8221; information into this prospectus, which means that we can disclose important information to you by referring you to other documents which we have filed or will file with the
      Commission.&#160; We are incorporating by reference in this prospectus the documents listed below and all amendments or supplements we may file to such documents, as well as any future filings we may make with the Commission on Form 20-F under the
      Exchange Act before the time that all of the securities offered by this prospectus have been sold or de-registered.&#160;&#160;</div>
    <div style="line-height: 1.25;">&#160;</div>
    <table cellspacing="0" cellpadding="0" style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; border-collapse: collapse; text-align: left; color: #000000;" id="z1902a2e68dcd483eb416a000874e909f">

        <tr>
          <td style="width: 7.97%; vertical-align: top;">
            <div style="line-height: 1.25;">&#160;</div>
          </td>
          <td style="width: 3.98%; vertical-align: top;">
            <div style="line-height: 1.25;">&#9679;</div>
          </td>
          <td style="width: 88.06%; vertical-align: top;">
            <div style="line-height: 1.25;">Our Annual Report on <a href="https://www.sec.gov/Archives/edgar/data/888721/000117891324001486/0001178913-24-001486-index.htm">Form 20-F</a> for the fiscal year ended December 31, 2023, as filed with the
              Commission on April 30, 2024;</div>
          </td>
        </tr>
        <tr>
          <td style="width: 7.97%; vertical-align: top;">
            <div style="line-height: 1.25;">&#160;</div>
          </td>
          <td style="width: 3.98%; vertical-align: top;">
            <div style="line-height: 1.25;">&#9679;</div>
          </td>
          <td style="width: 88.06%; vertical-align: top;">
            <div style="line-height: 1.25;">Our Reports on Form 6-K furnished to the Commission on <a href="https://www.sec.gov/Archives/edgar/data/888721/000117891324001483/zk2431344.htm">April 30, 2024</a>, <a href="https://www.sec.gov/Archives/edgar/data/888721/000117891324001767/zk2431479.htm">May 16, 2024</a>, <a href="https://www.sec.gov/Archives/edgar/data/888721/000117891324001848/zk2431512.htm">May 28, 2024</a>, <a href="https://www.sec.gov/Archives/edgar/data/888721/000117891324002176/zk2431659.htm">July 11, 2024</a>, <a href="https://www.sec.gov/Archives/edgar/data/888721/000117891324002190/0001178913-24-002190-index.htm">July 12, 2024</a>, <a href="https://www.sec.gov/Archives/edgar/data/888721/000117891324002473/zk2431795.htm">August 7, 2024</a>, <a href="https://www.sec.gov/Archives/edgar/data/888721/000117891324002475/zk2431796.htm">August 7, 2024</a>, <a href="https://www.sec.gov/Archives/edgar/data/888721/000117891324002706/zk2431900.htm">August 20, 2024</a>, <a href="https://www.sec.gov/Archives/edgar/data/888721/000117891324002726/zk2431905.htm">August 21, 2024</a>, <a href="https://www.sec.gov/Archives/edgar/data/888721/000117891324002843/zk2431954.htm">August 29, 2024</a>, <a href="https://www.sec.gov/Archives/edgar/data/888721/000117891324002977/zk2431993.htm">September 5, 2024</a> (with materials
              relating to the Company&#8217;s <a href="https://www.sec.gov/Archives/edgar/data/888721/000117891324002979/zk2431998.htm">annual general meeting</a>), <a href="https://www.sec.gov/Archives/edgar/data/888721/000117891324003121/zk2432055.htm">September








                23, 2024</a>, <a href="https://www.sec.gov/Archives/edgar/data/888721/000117891324003138/zk2432068.htm">September 25, 2024</a>, <a href="https://www.sec.gov/Archives/edgar/data/888721/000117891324003170/zk2432085.htm">September 30, 2024</a>,
              <a href="https://www.sec.gov/ix?doc=/Archives/edgar/data/888721/000117891324003210/zk2432086.htm">October 2, 2024</a>, October 25, 2024 (with respect to each of the <a href="https://www.sec.gov/Archives/edgar/data/888721/000117891324003365/zk2432170.htm">EpiCapture</a> acquisition and the <a href="https://www.sec.gov/Archives/edgar/data/888721/000117891324003367/zk2432171.htm">Novus</a> investment), <a href="https://www.sec.gov/Archives/edgar/data/888721/000117891324003523/zk2432250.htm">November 7, 2024</a>, <a href="https://www.sec.gov/Archives/edgar/data/888721/000117891324003735/zk2432323.htm">November 15, 2024</a>, <a href="https://www.sec.gov/Archives/edgar/data/888721/000117891324004052/zk2432488.htm">December 26, 2024</a>, <a href="https://www.sec.gov/Archives/edgar/data/888721/000117891325000249/zk2532619.htm">January 28, 2025</a>, <a href="https://www.sec.gov/Archives/edgar/data/888721/000117891325000251/zk2532620.htm">January 29, 2025</a>, <a href="https://www.sec.gov/Archives/edgar/data/888721/000117891325000318/zk2532651.htm">February 4, 2025</a>, <a href="https://www.sec.gov/Archives/edgar/data/888721/000117891325000349/zk2532668.htm">February 6, 2025</a>, <a href="https://www.sec.gov/Archives/edgar/data/888721/000117891325000649/zk2532784.htm">February 28, 2025</a>, <a href="https://www.sec.gov/Archives/edgar/data/888721/000117891325000823/zk2532861.htm">March 13, 2025</a> and <a href="https://www.sec.gov/Archives/edgar/data/888721/000117891325000840/zk2532869.htm">March 14, 2025</a>; and</div>
          </td>
        </tr>
        <tr>
          <td style="width: 7.97%; vertical-align: top;">
            <div style="line-height: 1.25;">&#160;</div>
          </td>
          <td style="width: 3.98%; vertical-align: top;">
            <div style="line-height: 1.25;">&#9679;</div>
          </td>
          <td style="width: 88.06%; vertical-align: top;">
            <div style="line-height: 1.25;">The description of our ADSs contained in our <a href="https://www.sec.gov/Archives/edgar/data/888721/000117891324001486/0001178913-24-001486-index.htm">Form 20-F</a> for the fiscal year ended December 31, 2023
              filed with the Commission on April 30, 2024.</div>
          </td>
        </tr>

    </table>
    <div style="text-indent: 36pt; line-height: 1.25;">&#160;</div>
    <div style="text-align: justify; text-indent: 36pt; line-height: 1.25;">In addition, we may incorporate by reference into this prospectus our reports on Form 6-K filed after the date of this prospectus (and before the time that all of the securities
      offered by this prospectus have been sold or de-registered) if we identify in the report that it is being incorporated by reference in this prospectus.</div>
    <div style="line-height: 1.25;">&#160;</div>
    <div style="text-align: justify; text-indent: 36pt; line-height: 1.25;">Certain statements in and portions of this prospectus update and replace information in the above listed documents incorporated by reference.&#160; Likewise, statements in or portions
      of a future document incorporated by reference in this prospectus may update and replace statements in and portions of this prospectus or the above listed documents.</div>
    <div style="line-height: 1.25;">&#160;</div>
    <div style="text-align: justify; text-indent: 36pt; line-height: 1.25;">
      <div style="text-indent: 36pt; line-height: 1.25; color: #000000; font-family: 'Times New Roman', serif;">We will provide you without charge, upon your written or oral request, a copy of any of the documents incorporated by reference in this
        prospectus, other than exhibits to such documents which are not specifically incorporated by reference into such documents. Please direct your written or telephone requests to Trinity Biotech plc, IDA Business Park, Bray, County Wicklow, Ireland,
        Attn: Corporate Secretary, telephone number +(353) 1 276 9800. You may also obtain information about us by visiting our website at www.trinitybiotech.com. Information contained in our website is not part of this prospectus.</div>
    </div>
    <div style="line-height: 1.25;"><br style="line-height: 1.25;">
    </div>
    <div style="text-align: justify; text-indent: 36pt; line-height: 1.25;">You should rely only on the information contained or incorporated in this prospectus. We have not authorized anyone else to provide you with different information. You should not
      rely on any other representations. Our affairs may change after this prospectus is distributed. You should not assume that the information in this prospectus is accurate as of any date other than the date on the front of those documents. You should
      read all information supplementing this prospectus.</div>
    <div style="text-align: justify; text-indent: 36pt; line-height: 1.25;"> <br>
    </div>
    <div style="text-align: justify; text-indent: 36pt; line-height: 1.25;">We are an Irish company and are a &#8220;foreign private issuer&#8221; as defined in Rule 3b-4 under the Exchange Act.&#160; As a result, (i) our proxy solicitations are not subject to the
      disclosure and procedural requirements of Regulation 14A under the Exchange Act, (ii) transactions in our equity securities by our officers, directors and principal shareholders are exempt from Section 16 of the Exchange Act; and (iii) we are not
      required under the Exchange Act to file periodic reports and financial statements as frequently or as promptly as U.S. companies whose securities are registered under the Exchange Act.</div>
    <div style="line-height: 1.25;"><br style="line-height: 1.25;">
    </div>
    <div style="clear: both; margin-top: 10pt; margin-bottom: 10pt;" class="BRPFPageBreakArea">
      <div class="BRPFPageNumberArea" style="text-align: center;"><font class="BRPFPageNumber" style="font-weight: normal; font-style: normal;">15</font></div>
      <div style="page-break-after: always;" class="BRPFPageBreak">
        <hr noshade="noshade" style="margin: 4px 0px; width: 100%; border-width: 0; height: 2px; color: #000000; background-color: #000000; clear: both;"></div>
    </div>
    <div style="text-align: center; line-height: 1.25; font-weight: bold;">ENFORCEABILITY OF CIVIL <a name="LIABILITIES"><!--Anchor--></a>LIABILITIES</div>
    <div style="line-height: 1.25;"><br style="line-height: 1.25;">
    </div>
    <div style="text-align: justify; text-indent: 36pt; line-height: 1.25;">Service of process upon us and upon our directors and officers and the Irish experts named in this prospectus, most of whom reside outside the United States, may be difficult to
      obtain within the United States.&#160; Furthermore, because substantially all of our assets and substantially all of our directors and officers are located outside the United States, any judgment obtained in the United States against us or any of our
      directors and officers may not be collectible within the United States.</div>
    <div style="line-height: 1.25;">&#160;</div>
    <div style="text-align: justify; text-indent: 36pt; line-height: 1.25;">We have been advised by counsel that the United States currently does not have a treaty with Ireland providing for the reciprocal recognition and enforcement of judgments in civil
      and commercial matters. Therefore, a final judgment for the payment of money rendered by any U.S. federal or state court based on civil liability, whether or not based solely on U.S. federal or state securities laws, would not automatically be
      recognized or enforceable in Ireland.</div>
    <div style="line-height: 1.25;">&#160;</div>
    <div style="text-align: justify; text-indent: 36pt; line-height: 1.25;">
      <div style="text-indent: 36pt; line-height: 1.25; color: #000000; font-family: 'Times New Roman', serif;">A judgment of the U.S. courts will be enforced by the Irish courts, by way of separate action in Ireland,&#160; if the following general requirements
        are met: (i) the debt is for a liquidated or defined sum; (ii) the procedural rules of the U.S. court must have been observed and the U.S. court must have had jurisdiction in relation to the particular defendant according to Irish conflict of law
        rules (the submission to jurisdiction by the defendant would satisfy this rule); and (iii) the judgment must be final and conclusive and the decree must be final and unalterable in the court which pronounces it. A judgment can be final and
        conclusive even if it is subject to appeal or even if an appeal is pending. If the effect of lodging an appeal under the applicable law is to stay execution of the judgment, it is possible that, in the meantime, the judgment should not be
        actionable in Ireland. It remains to be determined whether final judgment given in default of appearance is final and conclusive. However, the Irish courts may, in certain circumstances, refuse to enforce a judgment of the U.S. courts which meets
        the above requirements, including: (a) if the judgment is not for a debt or a definite sum of money; (b) if the judgment was obtained or alleged to have been obtained by fraud; (c) if the process and decision of the U.S. Courts were contrary to
        natural or constitutional justice under the laws of Ireland and if the enforcement of the judgment in Ireland would be contrary to natural or constitutional justice; (d) if the judgment is contrary to Irish public policy or involves certain United
        States laws which will not be enforced in Ireland or constitute the enforcement of a judgment of a penal or taxation nature; (e) if jurisdiction cannot be obtained by the Irish courts over the judgment debtors in the enforcement proceedings by
        personal service in Ireland or outside Ireland under Order 11 of the Irish Superior Courts Rules; (f) there is no practical benefit to the party in whose favor the foreign judgment is made in seeking to have that judgment enforced in Ireland, or
        (g) if the judgment is not consistent with a judgment of an Irish court in respect of the same matter.</div>
    </div>
    <div style="line-height: 1.25;">&#160;</div>
    <div style="text-align: justify; text-indent: 36pt; line-height: 1.25;">We have irrevocably appointed Puglisi &amp; Associates as our agent to receive service of process in any action against us in the state and federal courts sitting in the City of
      New York, Borough of Manhattan arising out of this offering or any purchase or sale of securities in connection therewith. We have not given consent for this agent to accept service of process in connection with any other claim.</div>
    <div style="line-height: 1.25;">&#160;</div>
    <div style="clear: both; margin-top: 10pt; margin-bottom: 10pt;" class="BRPFPageBreakArea">
      <div class="BRPFPageNumberArea" style="text-align: center;"><font class="BRPFPageNumber" style="font-weight: normal; font-style: normal;">16</font></div>
      <div style="page-break-after: always;" class="BRPFPageBreak">
        <hr noshade="noshade" style="margin: 4px 0px; width: 100%; border-width: 0; height: 2px; color: #000000; background-color: #000000; clear: both;"></div>
    </div>
    <div style="text-align: center; line-height: 1.25;"><img src="image00001.jpg"></div>
    <div style="line-height: 1.25;"><br style="line-height: 1.25;">
    </div>
    <div style="text-align: center; line-height: 1.25; font-weight: bold;">TRINITY BIOTECH PLC</div>
    <div style="line-height: 1.25;"><br style="line-height: 1.25;">
    </div>
    <div style="text-align: center; line-height: 1.25; font-weight: bold;">4,290,000 American Depositary Shares</div>
    <div style="text-align: center; line-height: 1.25; font-weight: bold;">representing</div>
    <div style="text-align: center; line-height: 1.25; font-weight: bold;">
      <div style="line-height: 1.25; color: #000000; font-family: 'Times New Roman', serif; font-weight: bold;">85,900,000 A Ordinary Shares</div>
    </div>
    <div style="line-height: 1.25;"><br style="line-height: 1.25;">
    </div>
    <div style="text-align: center; line-height: 1.25; font-weight: bold;">PROSPECTUS</div>
  </div>
  <div><br>
  </div>
  <div>
    <div style="text-align: center; line-height: 1.25;">March 31, 2025</div>
  </div>
  <div><br>
  </div>
  <br>
  <hr align="center" style="border: none; border-bottom: 4px solid black; border-top: 1px solid black; height: 10px; color: #ffffff; background-color: #ffffff; text-align: center; margin-left: auto; margin-right: auto;">
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end
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
