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Note 10 - Fair Values of Financial Instruments (Tables)
3 Months Ended
Mar. 31, 2016
Notes Tables  
Fair Value Inputs, Assets, Quantitative Information [Table Text Block]
Risk-free interest rate
0.40 - 1.12%
Expected term (years)
0.57 - 4.48
Expected dividends
  0  
Volatility of stock price
86.4% - 112.3%
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Table Text Block]
Warrant issued under PI SPA
       
Fair value at January 1, 2016
    7,478  
Gain on derivative
    (2,337
)
      5,141  
         
Warrant issued under September 2015 SPA
       
Fair value at January 1, 2016
    96,806  
Loss on derivative
    2,375  
      99,181  
         
Balance, March 31, 2016
  $ 104,322