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Note 10 - Fair Values of Financial Instruments (Tables)
6 Months Ended
Jun. 30, 2016
Notes Tables  
Fair Value Inputs, Assets, Quantitative Information [Table Text Block]
Risk-free interest rate
  0.27% - 0.89%
 
Expected term
  .32 - 4.23  
Expected dividends
    0    
Volatility of stock price
  74.3%  - 100.8%
 
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Table Text Block]
Warrant issued under PI SPA
       
Fair value at January 1, 2016
  $ 7,478  
Gain on derivative
    (1,904
)
      5,574  
Warrant issued under September 2015 SPA
 
Fair value at January 1, 2016
    96,806  
Loss on derivative
    51,410  
      148,216  
         
Balance, June 30, 2016
  $ 153,790