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Note 5 - Share Based Compensation - Expenses for Continuing Operations (Details) - USD ($) | 3 Months Ended | 6 Months Ended
--- | --- | ---
Jun. 30, 2019 | Jun. 30, 2018 | Jun. 30, 2019 | Jun. 30, 2018
Share-based compensation expense | $ 131,054 | $ 149,542 | $ 657,088 | $ 699,475
Selling, General and Administrative Expenses [Member] |  |  |  |
Share-based compensation expense | 115,526 | 128,620 | 568,613 | 599,766
Research and Development Expense [Member] |  |  |  |
Share-based compensation expense | $ 15,528 | $ 20,922 | $ 88,475 | $ 99,709

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