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Note 6 - Share Based Compensation - Expenses for Continuing Operations (Details) - USD ($) | 3 Months Ended | 9 Months Ended
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Sep. 30, 2021 | Sep. 30, 2020 | Sep. 30, 2021 | Sep. 30, 2020
Share-based compensation expense | $ 58,050 | $ 54,230 | $ 240,321 | $ 709,788
Selling, General and Administrative Expenses [Member] |  |  |  |
Share-based compensation expense | 47,694 | 51,157 | 207,342 | 632,793
Research and Development Expense [Member] |  |  |  |
Share-based compensation expense | $ 10,356 | $ 3,073 | $ 32,979 | $ 76,995

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